presentation1_Uncovering the Pharmacological Mechanism of 2-Dodecyl-6-Methoxycyclohexa-2,5 -Diene-1,4-Dione Against Lung Cancer Based on Network Pharmacology and Experimental Evalu... by Lihui Wang (437861)

“…Further tests showed that DMDD inhibited the proliferation, migration and clone formation in lung cancer cell lines (H1975 and PC9) in a dose and time dependent manner. Mechanistically, DMDD treatment decreased the expression of CDK2, CCNE1, E2F1 proteins and induced cell cycle arrest at the G1/S phase in H1975 and PC9 cells.…”

DataSheet_2_Reducedhumoral response against variants of concern in childhood solid cancer patients compared to adult patients and healthy children after SARS-CoV-2 vaccination.docx by Yifei Ma (206062)

“…</p>Results<p>The analysis included 111 CCP (27.2%, median age of 8, quartile 5.5–15 years), 134 CHC (32.8%), and 163 ACP (40.0%), for a total 408 patients. …”

Table 5_Integrative single-cell and bulk RNA-seq analyses identify CD4+ T-cell subpopulation infiltration and biomarkers of regulatory T cells involved in mediating the progression... by Yifeng Zhang (521454)

“…</p>Results<p>We found that the proportion of Tregs significantly decreased, and Th2 cells showed a significant increase in atherosclerotic plaque compared to that in non-plaque arterial tissues. …”

table1_Uncovering the Pharmacological Mechanism of 2-Dodecyl-6-Methoxycyclohexa-2,5 -Diene-1,4-Dione Against Lung Cancer Based on Network Pharmacology and Experimental Evaluation.x... by Lihui Wang (437861)

“…Further tests showed that DMDD inhibited the proliferation, migration and clone formation in lung cancer cell lines (H1975 and PC9) in a dose and time dependent manner. Mechanistically, DMDD treatment decreased the expression of CDK2, CCNE1, E2F1 proteins and induced cell cycle arrest at the G1/S phase in H1975 and PC9 cells.…”

DataSheet_1_Reducedhumoral response against variants of concern in childhood solid cancer patients compared to adult patients and healthy children after SARS-CoV-2 vaccination.docx by Yifei Ma (206062)

“…</p>Results<p>The analysis included 111 CCP (27.2%, median age of 8, quartile 5.5–15 years), 134 CHC (32.8%), and 163 ACP (40.0%), for a total 408 patients. …”

Relative activities of oxidizing enzymes in activated sludge during the stable stage. by Cong Jiang (3175146)

Scatterplot of fold-change expression for T-cell-specific mRNA transcripts in the whole blood. by Luísa Camacho (5508251)

“…The horizontal gray bars indicate a 2-fold increase and decrease in expression compared to control. …”

Scatterplot of fold-change expression for B-cell-specific mRNA transcripts in the whole blood. by Luísa Camacho (5508251)

“…The horizontal gray bars indicate a 2-fold increase and decrease in expression compared to control. …”

Inhibitory effect on other K⁺ channels. by Ancy Joseph (5634794)

“…Kir2.1 currents were evoked the step pulses, and application of 100 μM ostruthin decreased the currents by approximately 60% (n = 5). …”

N’-Ferrocenylmethyl-N’-phenylbenzohydrazide as a potential DNA binding compound: a combined experimental and computational study by Mouada Hanane (17308566)

“…Subsequently, the system was explored by computational molecular docking, confirming a non-covalent mode of binding <i>via</i> minor groove with a binding energy of −25.5 kJ/mol. …”

Hydro, wind and solar power as a base for a 100% renewable energy supply for South and Central America by Larissa de Souza Noel Simas Barbosa (3854164)

“…The results for total levelized cost of electricity (LCOE) are decreased from 62 €/MWh for a highly decentralized to 56 €/MWh for a highly centralized grid scenario (currency value of the year 2015). …”

The T120P or M172V mutation on <i>rv2172c</i> confers high level <i>para</i>-aminosalicylic acid resistance in <i>Mycobacterium tuberculosis</i> by Jin-Tian Xu (19171738)

“…The results showed that two mutations (T120P and M172V) on <i>rv2172c</i> could be identified in a certain proportion (6.36%) of PAS-resistant isolates. …”

Temperature and relative humidity inside the container holding the single N95 FFR during the 5 treatment cycles and the 6^th cycle in an “idli-cooker” (container with 4 F... by Siddharth Doshi (11506853)

Table_5_Endothelial Immunity Trained by Coronavirus Infections, DAMP Stimulations and Regulated by Anti-Oxidant NRF2 May Contribute to Inflammations, Myelopoiesis, COVID-19 Cytokin... by Ying Shao (200846)

“…Mechanistically, the ER stress and ROS, together with decreased mitochondrial OXPHOS complexes, facilitate a proinflammatory response and TI. …”

Fine Scale Structure in Cometary Dust Tails - Figure 6.7 - Temporal maps of C/2002 V1's dust tail from C3 Clear images with difference enhancement by Oliver Price (6774539)

“…A sequences of 70 temporal maps of C/2002 V1's main dust tail created from the SOHO LASCO C3 clear filter data, enhanced as temporal difference images.…”

DataSheet1_Controllable self-assembly of thiophene-based π-conjugated molecule and further construction of pillar[5]arene-based host-guest white-light emission system.docx by Haibo Zhong (129915)

“…More interestingly, when pillar[5]arene (P5) was added to form host-guest complex with TPPA, white light emission could be successfully constructed when the ratio of TPPA to P5 was 1:20 and THF to water was 19:1.…”

Image_5_Genome-Wide Survey of Leucine-Rich Repeat Receptor-Like Protein Kinase Genes and CRISPR/Cas9-Targeted Mutagenesis BnBRI1 in Brassica napus.tiff by Min Song (57124)

DataSheet_2_LncRNA xist regulates sepsis associated neuroinflammation in the periventricular white matter of CLP rats by miR-122-5p/PKCη Axis.pdf by Huifang Wang (390338)

“…Furthermore, it was found that the expression of IL-1β and TNF-α were negatively correlated with the level of miR-122-5p. A high-throughput sequencing analysis showed that miR-122-5p expression was downregulated with 1.5-fold changes in the PWM of CLP rats compared with sham group. …”

DataSheet_1_LncRNA xist regulates sepsis associated neuroinflammation in the periventricular white matter of CLP rats by miR-122-5p/PKCη Axis.zip by Huifang Wang (390338)

“…Furthermore, it was found that the expression of IL-1β and TNF-α were negatively correlated with the level of miR-122-5p. A high-throughput sequencing analysis showed that miR-122-5p expression was downregulated with 1.5-fold changes in the PWM of CLP rats compared with sham group. …”

DataSheet_1_Small RNA Expression Profiling Reveals hsa-miR-181d-5p Downregulation Associated With TNF-α Overexpression in Sjögren’s Syndrome Patients.doc by Isabel Castro (484905)

“…Levels of TNF-α mRNA, a direct target of hsa-miR-181d-5p, were significantly increased and negatively correlated with hsa-miR-181d-5p presence. …”