The T-type voltage-gated Ca²⁺ channel Ca_V3.1 involves in the disruption of respiratory epithelial barrier induced by <i>Pasteurella multocida</i> toxin by Haixin Bi (6867632)

“…In this study, we showed that inoculation of recombinantly expressed PMT increased the permeability of the respiratory epithelial barrier in mouse and respiratory cell models. This was evidenced by a decreased expression of tight junctions (ZO-1, occludin) and adherens junctions (β-catenin, E-cadherin), as well as enhanced cytoskeletal rearrangement. …”

Image1_LncRNA VPS9D1-AS1 Promotes Malignant Progression of Lung Adenocarcinoma by Targeting miRNA-30a-5p/KIF11 Axis.tif by Jiefeng Liu (9194412)

“…</p><p>Results: VPS9D1-AS1 and KIF11 were increased in LUAD, whereas miRNA-30a-5p was decreased. VPS9D1-AS1 promoted the malignant progression of LUAD cells and could sponge miRNA-30a-5p. …”

Table1_LncRNA VPS9D1-AS1 Promotes Malignant Progression of Lung Adenocarcinoma by Targeting miRNA-30a-5p/KIF11 Axis.xlsx by Jiefeng Liu (9194412)

“…</p><p>Results: VPS9D1-AS1 and KIF11 were increased in LUAD, whereas miRNA-30a-5p was decreased. VPS9D1-AS1 promoted the malignant progression of LUAD cells and could sponge miRNA-30a-5p. …”

Distribution of hookworm infections in different P/A/Ms in 2019 according to the national surveillance. by Hui-Hui Zhu (6506063)

Data_Sheet_1_Effectiveness of a program to lower unwanted media screens among 2–5-year-old children: a randomized controlled trial.docx by Nimran Kaur (11008865)

“…In the post-intervention assessment, 161 and 166 families continued while, at the follow-up assessment, 154 and 147 were in the intervention and control arm, respectively. The mean difference in ST on a typical day [27.7 min, 95% Confidence Interval (CI) 5.1, 50.3] at the post-intervention assessment significantly (p < 0.05) decreased in the intervention (102.6 ± 98.5 min) arm as compared with the control (130.3 ± 112.8 min) arm. …”

Data_Sheet_1_Effectiveness of a program to lower unwanted media screens among 2–5-year-old children: a randomized controlled trial.docx by Nimran Kaur (11008865)

“…In the post-intervention assessment, 161 and 166 families continued while, at the follow-up assessment, 154 and 147 were in the intervention and control arm, respectively. The mean difference in ST on a typical day [27.7 min, 95% Confidence Interval (CI) 5.1, 50.3] at the post-intervention assessment significantly (p < 0.05) decreased in the intervention (102.6 ± 98.5 min) arm as compared with the control (130.3 ± 112.8 min) arm. …”

The Impact of Prophylactic Dexamethasone on Nausea and Vomiting after Thyroidectomy: A Systematic Review and Meta-Analysis by Zhenhong Zou (645858)

“…Dexamethasone 8–10<b> </b>mg had a significantly greater effect for reducing the incidence of PONV than dexamethasone 1.25–5<b> </b>mg. …”

A Comparative Study of Neural and Mesenchymal Stem Cell-Based Carriers for Oncolytic Adenovirus in a Model of Malignant Glioma by Atique U. Ahmed (226456)

“…Loading oncolytic adenovirus into NSCs and MSCs also led to expression of both pro- and anti-inflammatory genes and decreased vector-mediated neuroinflammation. Our results indicate that, despite possessing a comparable migratory capacity, NSCs display superior therapeutic efficacy in the context of intracranial tumors. …”

Early mobilization of critically ill patients in the intensive care unit: A systematic review and meta-analysis by Lan Zhang (90951)

“…Early mobilization decreased the incidence of ICU-acquired weakness (ICU-AW) at hospital discharge (three studies, 190 patients, relative risk (RR): 0.60, 95% confidence interval (CI) [0.40, 0.90]; <i>p</i> = 0.013, <i>I</i>^<i>2</i> = 0.0%), increased the number of patients who were able to stand (one study, 50 patients, 90% vs. 62%, <i>p</i> = 0.02), increased the number of ventilator-free days (six studies, 745 patients, standardized mean difference (SMD): 0.17, 95% CI [0.02, 0.31]; <i>p</i> = 0.023, <i>I</i>^<i>2</i> = 35.5%) during hospitalization, increased the distance the patient was able to walk unassisted (one study, 104 patients, 33.4 (0–91.4) meters vs. 0 (0–30.4) meters, <i>p</i> = 0.004) at hospital discharge, and increased the discharged-to-home rate (seven studies, 793 patients, RR: 1.16, 95% CI [1.00, 1.34]; <i>p</i> = 0.046). …”

Clearance of PAG concentrations in postpartum beef cattle (A) and overall comparison between parity (B). by Adalaide C. Kline (19226172)

Viability of FTY720-treated T_CM A. by Rachel S. Resop (9238645)

During electrical stimulation the decrease in compound action potential (CAP), but not of ATP, is larger in <i>Plp</i>^null/y mice. by Andrea Trevisiol (9647910)

SDS-PAGE (10%) of culture supernatant of representative HESA-derived Tn5 mutants H28–35 (Table 1) cultured for 16 h. by Marion Schoof (11999106)

Histogram of gastroenteritis in a rural village, Kazakhstan, May–June 2021 (N = 154). by Madina Orysbayeva (14241331)

A T-test mean comparison of pre and post COVID-19 differences for selected variables. by Beshir Bedru Nasir (8218863)

Clinical outcome at 60 days based on SaFi, anakinra and a simplified SCOPE. by Ismael Francisco Aomar-Millán (14838595)

<i>USP28</i> protein level was decreased by hypoxia signaling via both protein degradation and transcriptional repression in A549 cells. by Qin Li (36669)

“…After treatment, cells were lysed and 50 µg of whole cell lysate was analyzed by Western blotting. …”

Longer <i>L</i>_<i>h</i> significantly decreases and delays the peak of the sound-evoked CAPs of SGN fibers. by Maral Budak (6680351)

“…<p>(A) Sound-evoked CAPs of SGN fiber populations of varying heminode length <i>L</i>_<i>h</i> at 70dB SPL, averaged over 50 simulations. Shaded regions correspond to the standard error of the mean and dashed lines correspond to the peaks of each CAP, labeled with the same colors as the CAPs. …”

Image_10_In Vitro Characterization of 177Lu-DOTA-M5A Anti-Carcinoembryonic Antigen Humanized Antibody and HSP90 Inhibition for Potentiated Radioimmunotherapy of Colorectal Cancer.t... by Tabassom Mohajershojai (9441050)

“…Moreover, the heat shock protein 90 inhibitor onalespib has previously demonstrated radiotherapy potentiation effects in vivo. In the present study, a ¹⁷⁷Lu-radiolabeled anti-CEA hT84.66-M5A mAb (M5A) conjugate was developed and the potential therapeutic effects of ¹⁷⁷Lu-DOTA-M5A and/or onalespib were investigated. …”

Image_1_In Vitro Characterization of 177Lu-DOTA-M5A Anti-Carcinoembryonic Antigen Humanized Antibody and HSP90 Inhibition for Potentiated Radioimmunotherapy of Colorectal Cancer.ti... by Tabassom Mohajershojai (9441050)

“…Moreover, the heat shock protein 90 inhibitor onalespib has previously demonstrated radiotherapy potentiation effects in vivo. In the present study, a ¹⁷⁷Lu-radiolabeled anti-CEA hT84.66-M5A mAb (M5A) conjugate was developed and the potential therapeutic effects of ¹⁷⁷Lu-DOTA-M5A and/or onalespib were investigated. …”