A2PP has minimal effects on EGFR-ANXA2 signaling, migration of gastric cancer cells, or the localization of ANXA2. by Shiqin Yuan (848670)

IDD388 Polyhalogenated Derivatives as Probes for an Improved Structure-Based Selectivity of AKR1B10 Inhibitors by Alexandra Cousido-Siah (777034)

“…Starting from the potent AR inhibitor IDD388, we have synthesized a series of derivatives bearing the same halophenoxyacetic acid moiety with an increasing number of bromine (Br) atoms on its aryl moiety. Next, by means of IC₅₀ measurements, X-ray crystallography, WaterMap analysis, and advanced binding free energy calculations with a quantum-mechanical (QM) approach, we have studied their structure–activity relationship (SAR) against both enzymes. …”

The expression of PrP^C on mouse bone marrow (BM) and spleen erythroid precursors is upregulated in early erythroblasts and, then, decreases with the cells' maturation. by Martin Panigaj (345008)

“…Expression of PrP^C on early basophilic erythroblasts (EryA) is significantly higher (p>0.005, n = 5) in comparison with proerythroblasts (ProE), both in BM (upper) and spleen (lower). …”

Table_5_SARS-CoV-2 antibody responses before and after a third dose of the BNT162b2 vaccine in Italian healthcare workers aged ≤60 years: One year of surveillance.xlsx by Monica Franzese (8983097)

“…The cohorts were monitored from the 12th day after the first vaccine dose up to 1 month after the third vaccine dose for a total of eight time points and about 1 year of surveillance (T1 = 12 days after the first dose; T2 = 10 days after the second dose; T3 = 1 month after the second dose; T4 = 3 months after the second dose; T5 = 4 months after the second dose; T6 = 5 months after the second dose; T7 = 7 months after the second dose; T8 = 1 month after the third dose for Group 1; T8* = 9 months after the second dose for Group 2; T9 = 1 month after the third dose for Group 2). …”

The effect of NAC on decreased ERK1/2 Tyr-204 phosphorylation caused by arecoline during myogenic differentiation in C2C12 cells. by Yi-Xuan Li (6633845)

Mutations close to a hub residue affect the distant active site of a GH1 β-glucosidase by Valquiria P. Souza (3392195)

“…Next to V336, mutation S337F also caused a decrease in noncovalent interactions involved in transition state stabilization. …”

Stability diagram in the plane for plane-wave propagation through a mural slice of our 2D simulation domain with a random distribution of myocytes and fibroblasts. by Rupamanjari Majumder (128411)

Stability diagram in the plane for plane-wave propagation through a transmural slice of our 2D simulation domain with a random distribution of myocytes and fibroblasts. by Rupamanjari Majumder (128411)

Patient data. by Alexander Neugebauer (2425123)

“…Both effects are significantly higher than those found in the control phase (<i>p</i> < 0.001 for required time, <i>p</i> = 0.0165 for number of collisions), with the required time decreasing by 5.9% and number of collisions decreasing by 10.4% after the control phase. …”

Genetic deletion of P2rx7 leads to the alteration of NA and 5-HT levels (A, B), elevation of³H-Citalopram binding sites and 5-HT uptake (C) in the mouse hippocampus. by Cecilia Csölle (425362)

“…<p>A, B/NA and 5-HT levels were analyzed using HPLC in the hippocampus of naive and LPS (1 mg/kg)-treated P2rx7+/+ and P2rx7−/− mice. …”

Data Sheet 1_Dynamic SARS-CoV-2-specific B-cell and T-cell responses induced in people living with HIV after a full course of inactivated SARS-CoV-2 vaccine.docx by Xiuwen Wang (267423)

“…Objective<p>Both B-cell- and T-cell-mediated immunity are crucial for the effective clearance of viral infection, but little is known about the dynamic characteristics of SARS-CoV-2-specific B-cell and T-cell responses in people living with HIV (PLWH) after a full course of inactivated SARS-CoV-2 vaccination.…”

Structural Phase Transition between γ‑Ti₃O₅ and δ‑Ti₃O₅ by Breaking of a One-Dimensionally Conducting Pathway by Kenji Tanaka (692662)

“…Optical measurement also supports that γ-Ti₃O₅ is a metallic conductor, while δ-Ti₃O₅ is a semiconductor with a band gap of 0.07 eV. …”

Structural Phase Transition between γ‑Ti₃O₅ and δ‑Ti₃O₅ by Breaking of a One-Dimensionally Conducting Pathway by Kenji Tanaka (692662)

“…Optical measurement also supports that γ-Ti₃O₅ is a metallic conductor, while δ-Ti₃O₅ is a semiconductor with a band gap of 0.07 eV. …”

Elevated IL-18, NF-κB p65, and YY1 expression and decreased FXR and MRP2 were observed in the BDL rats. by Xiao-cong Liu (785281)

DataSheet_1_SARS-CoV-2-Specific IgG and IgA response in maternal blood and breastmilk of vaccinated naïve and convalescent lactating participants.docx by Yesica Longueira (13896795)

“…</p>Methods<p>Here, we evaluated anti-SARS-CoV-2 IgG and IgA levels in both serum and milk samples using a longitudinal and a cross-sectional cohort of 208 breastfeeding vaccinated women from Argentina with or without previous SARS-CoV-2 infection.…”

Decreased accumulation of CD4⁺ T cells and CD19⁺ B cells in DLN of old mice after immunization with ovalbumin. by Justin M. Richner (213025)

Thy1-p45 transgenic mice have decreased retraction of CST fibers and improved functional recovery following SCI compared to their WT littermates. by Tsung-Chang Sung (436234)

Oral Administration of <i>Faecalibacterium prausnitzii</i> Decreased the Incidence of Severe Diarrhea and Related Mortality Rate and Increased Weight Gain in Preweaned Dairy Heifer... by Carla Foditsch (408566)

Antiviral activity of RDV and EIDD2801 in Vero-ACE-2 against three continually passaged populations and the input SARS-CoV-2_Engl2. by Agnieszka M. Szemiel (10196243)

The classification proportions across cross-sectional age over five select cognitive systems: a) auditory-left (Aud-L; dark blue), b) auditory-right (Aud-R; dark purple), c) ventra... by Andrew Patton (10224161)