CStS recapitulate MSNs degeneration observed in R6/2 mouse model. by Catia C. Proenca (431486)

“…Neurodegeneration is observed as a decrease in marker intensity. F) Left: quantification for the ratio of striatal NeuN and DAPI positive nuclei in WT and R6/2 slices at DIV21. …”

Ionizing radiation–induced DSBs and repair. by Jim Westmoreland (260234)

“…<p>Haploid cells growing logarithmically in YPDA media were arrested at G2/M with nocodazole and γ-irradiated with 5 to 80 krads from a Cs source. Cells from the 80 krad dose were returned to YPDA containing nocadazole and incubated for up to 4 hours to allow repair of DSBs (A) DSBs and repair in WT and <i>exo1Δ</i> strains. …”

ROP18 directly phosphorylates Irga6 at T102 and T108 in vitro. by Tobias Steinfeldt (154465)

“…The autoradiogram reveals efficient phosphorylation of wt Irga6 and a decrease in signal intensity for all Irga6 alanine mutants. …”

A Reappraisal of the Mechanism by Which Plant Sterols Promote Neutral Sterol Loss in Mice by Gemma Brufau (215229)

“…PS feeding resulted in a dose-dependent decrease of fractional cholesterol absorption (∼2–7-fold reduction) in wild-type mice and ∼80% reduction in Abcg5^-/- mice. …”

Developmental changes in DKO mice. by Lindsay Wieczorek (171734)

“…<p>Two genes identified with microarray analysis and showing the most significant change between WT and DKO mice, (<b>A</b>) Slc11a2 (n = 5, *p≤0.0001), with a −1.3 fold change, and (<b>B</b>) Lynx1 (n = 5, *p≤0.0001), with −1.4 fold change, were confirmed via RT-PCR. …”

Influence of MgCl and ATP on primer unblocking by AZT-resistant RT by Valérie Goldschmidt (13343)

“…All rights reserved</p> () ssDNA synthesis was performed in the presence of 3.5 mM ATP and 4 µM AZTTP with wt or AZT-resistant RT at 2 or 6 mM MgCl. …”

Image_3_Resting Heart Rate Variability Is Associated With Subsequent Orthostatic Hypotension: Comparison Between Healthy Older People and Patients With Rapid Eye Movement Sleep Beh... by Yukiyoshi Sumi (5290874)

“…The multivariate logistic regression analysis for OH identification for the iRBD groups showed the model whose inputs were the HRV indices, i.e., standard deviation 2 (SD2) and the percentage of adjacent intervals that varied by more than 50 ms (pNN50), had a receiver operating characteristic curve with area under the curve of 0.840, the sensitivity to OH (+) of 1.000, and the specificity to OH (–) of 0.583 (p = 0.023).…”

Table_1_Resting Heart Rate Variability Is Associated With Subsequent Orthostatic Hypotension: Comparison Between Healthy Older People and Patients With Rapid Eye Movement Sleep Beh... by Yukiyoshi Sumi (5290874)

“…The multivariate logistic regression analysis for OH identification for the iRBD groups showed the model whose inputs were the HRV indices, i.e., standard deviation 2 (SD2) and the percentage of adjacent intervals that varied by more than 50 ms (pNN50), had a receiver operating characteristic curve with area under the curve of 0.840, the sensitivity to OH (+) of 1.000, and the specificity to OH (–) of 0.583 (p = 0.023).…”

Image_2_Resting Heart Rate Variability Is Associated With Subsequent Orthostatic Hypotension: Comparison Between Healthy Older People and Patients With Rapid Eye Movement Sleep Beh... by Yukiyoshi Sumi (5290874)

“…The multivariate logistic regression analysis for OH identification for the iRBD groups showed the model whose inputs were the HRV indices, i.e., standard deviation 2 (SD2) and the percentage of adjacent intervals that varied by more than 50 ms (pNN50), had a receiver operating characteristic curve with area under the curve of 0.840, the sensitivity to OH (+) of 1.000, and the specificity to OH (–) of 0.583 (p = 0.023).…”

Image_1_Resting Heart Rate Variability Is Associated With Subsequent Orthostatic Hypotension: Comparison Between Healthy Older People and Patients With Rapid Eye Movement Sleep Beh... by Yukiyoshi Sumi (5290874)

“…The multivariate logistic regression analysis for OH identification for the iRBD groups showed the model whose inputs were the HRV indices, i.e., standard deviation 2 (SD2) and the percentage of adjacent intervals that varied by more than 50 ms (pNN50), had a receiver operating characteristic curve with area under the curve of 0.840, the sensitivity to OH (+) of 1.000, and the specificity to OH (–) of 0.583 (p = 0.023).…”

The increased myeloid priming of Id1 null HSCs requires the expression of p21 by Alessia Ciarrocchi (37383)

“…Numbers indicate average colony numbers±SEM (WT 1.5±0.64 n = 4; Id1-/- 3.8±0.58 n = 5; Id1-/-p21-/- 0.5±0.28 n = 4; p21-/- 1±0.40 n = 4) D) Quantitative real time PCR analysis of c/EBPα mRNA levels in sorted HSCs. …”

BIOMECHANICAL, COORDINATIVE, AND PHYSIOLOGICAL RESPONSES TO A TIME-TO-EXHAUSTION PROTOCOL AT TWO SUBMAXIMAL INTENSITIES IN SWIMMING by Marcos Franken (8184234)

Gene expression of <i>Iex-1</i> and <i>Vegf-A</i> by qRT-PCR in outflow vein of AVF seven days after adventitial delivery of hydrogel alone, hydrogel with nanoparticle PLGA without... by Akshaar Brahmbhatt (551498)

Presynaptic marker CtBP2 counts of the IHCs and OHCs. by Pezhman Salehi (4528993)

“…CtBP2 counts of the IHCs showed two cochlea out of five with nearly 50% decreased numbers of the puncta when compared to WT controls; however, the average of the counts (five cochlea) did not show a statistically significant difference (D). …”

Reduction in DRG neuronal numbers following error correction. by Ayal Ben-Zvi (438134)

“…<p>Graph representing estimates of DRG neuronal total number. L5 DRG of P0 mice were used as an end point of the error correction period. …”

Effects of <i>tel1Δ rad3Δ</i> mutations on recruitment of telomere capping complexes. by Bettina A. Moser (260302)

“…Compared to wt cells, only <i>tel1Δ rad3Δ</i> (P = 0.006) had a significant decrease in Tpz1 binding, while decreases in <i>tel1Δ</i> (P = 0.108) and <i>rad3Δ</i> (P = 0.170) were not significant. …”

The hydration and alteration of perlite and rhyolite by J.S. Denton (2846327)

Siah1/2-dependent gene expression analysis confirms an ER stress signature. by Marzia Scortegagna (561529)

“…Panel c shows genes from pairwise comparisons: ko versus wt, koTG versus wtTG and koTM versus wtTM. (D) Principal component analysis (PCA) 3D plot for the microarray data set. …”

Effect of anisotropy. by Diarmuid J. Cahalane (233294)

Functional effects of a Cdk5 inhibitor and/or GSK-3β inhibitor on the survival of pINT-EGFP cells. by Wen-Ching Lee (141923)

“…Original magnification: ×20, Scale bar: 50 µm. (B) Caspase-3 activity detected by casp-3 BDP levels. …”