CX3CL1 (Fractalkine) Protein Expression in Normal and Degenerating Mouse Retina: <i>In Vivo</i> Studies by Marina Zieger (626340)

“…The immunoblots revealed that in both, wt and rd10 retinas, a membrane integrated ∼100 kDa CX3CL1 form and a cleaved ∼85 kDa CX3CL1 form were present at P5. …”

Ras transformation affects the circadian clock via MAPK signalling. by Angela Relógio (193817)

“…<p>(<b>A</b>) Shown are <i>in silico</i>-generated gene expression oscillations with wild type (WT) in blue, RAS overexpressing in red (i.e., reducing the BMAL1 mediated-transcription by 60% (ktt = 0.4) compared to WT) and reducing RAS activity (i.e., increasing BMAL1 mediated-transcription by 60% (ktt = 1.6)) in green. …”

Behavioral sleep and automated scoring in the Argentine tegu (<i>S</i>. <i>merianae</i>). by Paul-Antoine Libourel (561599)

“…Representation over 24 h of the time spent inside (black bars) the shelter for each of the five animals recorded (top); mean ± SEM (line and gray zone) percentage of awakenings induced by a sensory stimulation made every hour (<i>n</i> = 5 animals); the mean ± SEM number of eye movements per hour; the mean ± SEM heart rate per hour. …”

Ischemic preconditioning (IPC) does not occur in Cav-1 KO mice. by Brian P. Head (343968)

“…Representative Cresyl Violet stained CA1 hippocampal images from (<b>i</b>) WT sham, (<b>ii</b>) WT IPC, (<b>iii</b>) WT LI, and (<b>iv</b>) WT IPC and (<b>v</b>) Cav-1 KO sham, (<b>vi</b>) Cav-1 KO IPC, (<b>vii</b>) Cav-1 KO LI, and (<b>viii</b>) Cav-1 KO IPC. …”

Effect of hypotonic stress and elevated K⁺ on the ECS diffusion parameters in α-syn +/+ and α-syn −/− mice <i>in vitro</i>. by Lesia Dmytrenko (431060)

“…The mean values of the maximum change during application correspond to the time-point of the maximum decrease of α (i.e., the 25^th min in H-50 and H-100 and the 30^th min in 10 mM K⁺); the values for washout correspond to the data point at the 90^th min. …”

Nilotinib binds to SMO and competes with Cyclopamine and SAG. by Kirti Kandhwal Chahal (7411091)

“…Mebendazole did not demonstrate any appreciable displacement of BODIPY-Cyclopamine in this assay. Data represent the mean and standard deviation for two independent experiments, max GMFI: Maximum Geometric Mean Fluorescence Intensity; UT: Untransfected HEK293T cells (<b>c)</b> Concentration response curve of SAG in the Gli-Luciferase functional assay in the absence or presence of inhibitors: Nilotinib or Vismodegib shifted EC₅₀ of SAG to the right without decrease in maximal response, suggesting a competitive relationship. …”

Expression of BDNF in retinas after 6 weeks of diabetes onset in SE- or EE-housed animals. by Damián Dorfman (293002)

“…Data are the mean ± SEM (n = 5 eyes per group); **p<0.01, versus age-matched controls; a: p<0.01, versus diabetic animals housed in SE, by Tukey's test. …”

PAN RNA interacts with demethylases and the histone methyltransferase MLL2. by Cyprian C. Rossetto (107771)

“…(B) PAN RNA expression leads to a relative decrease in the H3K27me3 mark on the ORF50 promoter. …”

The percentage of cells with protein aggregates cotransfected with αA- and αB-crystallin or R120G αB-crystallin (αBM) genes by Bing-Fen Liu (81305)

“…For each experiment, cells were counted in 30-50 confocal LSM images.…”

DHA pre-treatment of <i>H. pylori</i> leads to a reduced inflammatory response. by Marta Correia (170478)

“…Pre-treatment of bacteria with DHA from 50 µM to 250 µM led to a significant decrease of 4-fold in IL-8 production as compared to non-DHA treated bacteria * P<0.05. …”

Figure S1 - Electrical Stimuli Are Anti-Apoptotic in Skeletal Muscle via Extracellular ATP. Alteration of This Signal in Mdx Mice Is a Likely Cause of Dystrophy by Denisse Valladares (489234)

“…We observed the maximum decrease in mRNA levels when using a concentration of 100 µM in normal fibers (A), while the maximum values were found for 50 and 100 µM in dystrophic fibers (B) (n = 4). …”

Table_1_Central Multifocal Choroiditis: Platelet Granularity as a Potential Marker for Treatment With Steroid-Sparing Immunomodulatory Therapy.docx by Evianne L. de Groot (11937257)

Remodeling of Purkinje dendrites in the third postnatal week. by Megumi Kaneko (219519)

“…<b>D</b>: Overpassing branches per cell peak at P18, sharply decrease by P22 and plateau thereafter. <b>E</b>: The mean length of each dendritic branch decreases between P7 and P9, constantly increases until P35 and then slightly decreased by P50. …”

Reproduction of ventral furrow formation. by Philipp Spahn (458913)

Modulation of AChR and GABA_R can restore post-synaptic folding. by M. Catarina Silva (189975)

“…(F) Real-time qPCR analysis of <i>hsp-70</i> (<i>C12C8.1, F44E5.4</i>) levels in 5 day old wt animals upon treatment with ACh, levamisole or the GABA_R antagonist Lindane, or upon decrease in GABAergic signaling by either RNAi or mutant backgrounds of <i>unc-47(gk192)</i>, <i>unc-49(e407)</i> or <i>unc-30(e191)</i>. …”

The hypothalamic-pituitary-thyroid axis in TRH deficient mice. by Yasuyo Nakajima (316579)

“…The TSHβ mRNA level in TRH−/− was decreased to about 50% of that in the wild-type, and that of TRH−/−+T4 mice was further decreased to about 10% (n = 3, <i>p<</i>0.01). **, <i>p</i><0.01. …”

ECG analyses of urethane anaesthetized Ts65Dn adult mice revealed cardiac conduction anomalies. by Matthieu Raveau (160575)

“…Measurement of wave amplitudes in precordial leads (G) showed a large decrease of S and J waves on V1 and limited changes in V4 whereas R waves were found normal in both V1 and V4 (n = 31 and 29 for wt and Ts65Dn respectively) (Student t-test p-values: **: <i>P</i><0.01; ***: <i><u>P</u></i><0.001).…”

The probability of tumor nodule eradication increases with the increase of CTL number. by Claire Christophe (714134)

“…Other lines: same evolution when the mean killing time is decreased by 10%, 50% and 90%. …”

Mef2C is regulated during neurogenesis, in turn contributing to miR-9 induction. by Jonathan L. Davila (548756)

“…(C) Deletion of Mef2 binding sites in the upstream regulatory region diminishes transcription activity of the miR-9-2 gene locus. A 5 kb upstream sequence of the rat miR-9-2 gene was cloned into the promoter-less pGL4.10 luciferase reporter vector (wild-type, WT). …”

Controls for fitness experiments and Phosphosite Scanning. by Michelle M. Conti (13514386)

“…Plasmid expressed copies of Hcm1 are tagged with V5 and were expressed throughout the experiment. …”