DataSheet_1_PPARG dysregulation as a potential molecular target in adrenal Cushing's syndrome.zip by Sharmilee Vetrivel (10176326)

“…Quantitative PCR (QPCR) confirmed that PPARG (l2fc<-1.5) and related genes – FABP4 (l2fc<-5.5), PLIN1 (l2fc<-4.1) and ADIPOQ (l2fc<-3.3) – were significantly downregulated (p<0.005) in PBMAH. …”

Data_Sheet_1_Novel Compound Missense and Intronic Splicing Mutation in ALDH18A1 Causes Autosomal Recessive Spastic Paraplegia.docx by Yi-Jun Chen (444508)

“…ELISA assays revealed significantly decreased P5CS concentration in the proband's plasma compared with that in the healthy controls. …”

Data Sheet 1_Rising burden of subarachnoid hemorrhage linked to high systolic blood pressure among young and middle-aged populations: temporal trends and global implication.pdf by Pengfei Chen (462170)

“…From 1990 to 2021, high-SDI regions achieved the greatest reductions in mortality (−50.3%) and DALYs (−46.8%), while low-SDI regions saw increases in deaths (+109.5%) and DALYs (+114.7%). Nationally, Zimbabwe and Guatemala showed the sharpest increases in mortality (EAPC: +4.71% and +3.76%), while Sweden and Swiss Confederation achieved the greatest declines (EAPC: −5.5% and −4.9%). …”

Data Sheet 1_The impact of environmental contaminants, air pollution, and social deprivation on childhood leukemia survival in California.docx by Fernando Hernandez (22801319)

“…</p>Results<p>124 out of 1,210 children with acute lymphoblastic leukemia (ALL) died within 5 years of diagnosis. Living in an area with a medium/high CES composite score for both pollution and population/social burdens was associated with decreased ALL survival, compared to a low CES score (HR = 2.19; 95% CI: 1.19-3.91), with population/social burden driving this observation (HR = 1.85; 95% CI: 1.06-3.21). …”

Data Sheet 1_Global assessment of terrestrial precipitation and evapotranspiration in CMIP6 simulations using observation-based estimates.docx by Shanshan Sun (275585)

“…</p>Methods<p>This study evaluates historical simulations from Phase Six of the Coupled Model Intercomparison Project (CMIP6) for precipitation (Pr), evapotranspiration (ET), and its components—soil evaporation (Es), transpiration (Et), and interception loss (Ei)—from 1981 to 2014, focusing on the temporal agreement of the mean seasonal cycle and interannual variability. We assess these variables using observation-based estimates from three Pr datasets (CRU4.0, GPCP v2.3, ERA5) and four land surface flux datasets (GLEAM v3.3a, GLDAS v2.0, ERA5-Land, MERRA-Land). …”

Evolutionary and Biotechnological Implications of Robust Hydrogenase Activity in Halophilic Strains of Tetraselmis by Sarah D'Adamo (511712)

“…The influence of salinity (3.5%, 5.5% and 7.0% w/v NaCl) on H₂ production was examined during anoxic acclimation, with the greatest in vivo H₂-production rates observed at 7.0% NaCl. …”

Image 9_Potential marker genes for psoriasis revealed based on single-cell sequencing and Mendelian randomization analysis.tif by Ying Dong (41989)

“…Among them, BIN2 and CAPN12 were linked to an increased risk, while genes such as CXXC5 and KLRD1 were associated with decreased risk. …”

ORCID uptake in pharma-sponsored research by Caitlin Edgell (10571574)

“…The proportion of ORCID iDs belonging to authors who are pharma employees decreased (11.5% vs 17.5% previously).</p> <p><strong>Conclusions</strong></p> <p>ORCID iD registration by pharma employees and use by authors in pharma-sponsored publications are increasing. …”

datasheet1_Air Pollution in a Low-Industry City in China’s Silk Road Economic Belt: Characteristics and Potential Sources.pdf by Fanglong Wang (10222724)

“…The results show that SO₂ and CO had a decreasing trend and NO₂, O₃, PM_2.5, and PM₁₀ had an increasing trend during the study period. …”

Data Sheet 2_Potential marker genes for psoriasis revealed based on single-cell sequencing and Mendelian randomization analysis.csv by Ying Dong (41989)

“…Among them, BIN2 and CAPN12 were linked to an increased risk, while genes such as CXXC5 and KLRD1 were associated with decreased risk. …”

Table_1_Cardiorespiratory fitness attenuates the association between fatness and cardiometabolic risk in Chinese children.docx by Ping-Ping Zhang (5014139)

“…Specifically, CRF mediated 6.5%, 7.7%, 5.3%, and 12.5% of the association between BMI, BMI z score, BFMI, WHtR and CMR-score (all P < 0.001). …”

Supplementary Material for: Changes in the Small Bowel of Symptomatic Kidney Transplant Recipients Converted from Mycophenolate Mofetil to Enteric-Coated Mycophenolate Sodium by Bunnapradist S. (4147492)

“…Subjects' median ages and post-transplant time were 47.5 years old and 4.5 months, respectively. Tacrolimus, MMF and prednisone was the main regimen (94%), with a median MMF dose of 750 mg BID. …”

Image 6_Potential marker genes for psoriasis revealed based on single-cell sequencing and Mendelian randomization analysis.tif by Ying Dong (41989)

“…Among them, BIN2 and CAPN12 were linked to an increased risk, while genes such as CXXC5 and KLRD1 were associated with decreased risk. …”

Data_Sheet_1_Zooplankton-Mediated Fluxes in the Eastern Tropical North Atlantic.pdf by Rainer Kiko (758773)

“…Integrated mesozooplankton biomass in the ETNA region is about twice as high at a central OMZ location (cOMZ; 11° N, 21° W) compared to the Cape Verde Ocean Observatory (CVOO; 17.6° N, 24.3° W) and an oligotrophic location at 5° N, 23° W (5N). An Intermediate Particle Maximum (IPM) is particularly strong at cOMZ compared to the other regions. …”

DataSheet2_Mating Stimulates the Immune Response and Sperm Storage-Related Genes Expression in Spermathecae of Bumblebee (Bombus terrestris) Queen.docx by Yueqin Guo (11757317)

“…In total, the expression of 11, 069 and 10, 862 genes were identified in virgins and mated queens, respectively. We identified that 176 differentially expressed genes between virgin and mated queen spermathecae: 110 (62.5%) genes were upregulated, and 66 (37.5%) genes were downregulated in mated queens. …”

Table_3_Improved targeting of the 16S rDNA nanopore sequencing method enables rapid pathogen identification in bacterial pneumonia in children.docx by Yinghu Chen (14347284)

“…With an abundance threshold increase of 1%, 5%, 10%, 15% and 20%, the test sensitivity decreased gradually to 98.6%, 84.9%, 72.6%, 67.1% and 64.4%, respectively, and the test specificity increased gradually to 33.3%, 71.4%, 81.0%, 90.5% and 100.0%, respectively.…”

Development and Progression of Diabetic Retinopathy in Adolescents and Young Adults With Type 2 Diabetes: Results From the TODAY Study by Rose Gubitosi-Klug (10513924)

“…<p><b>Objective</b>: The Treatment Options for type 2 Diabetes in Adolescents and Youth (TODAY) trial reported a 13.9% prevalence of diabetic retinopathy (DR) in youth with an average 4.9 ± 1.5 years of type 2 diabetes duration. After seven years of additional follow up, we report the risk factors for progression of DR in the TODAY cohort. …”

DataSheet_1_Lifetime risk and health-care burden of diabetic ketoacidosis: A population-based study.docx by Fahim Ebrahimi (6627524)

“…Incidence rates of DKA among patients with type 1 diabetes were highest during adolescence with 17.67 (girls) and 13.87 (boys) events per 100,000 person-years (incidence rate difference [IRD]: -3.80 [95% CI, -5.59 to -2.02]) and decreased with age in both sexes thereafter. …”

Table 9_Potential marker genes for psoriasis revealed based on single-cell sequencing and Mendelian randomization analysis.xlsx by Ying Dong (41989)

“…Among them, BIN2 and CAPN12 were linked to an increased risk, while genes such as CXXC5 and KLRD1 were associated with decreased risk. …”

DataSheet1_Mating Stimulates the Immune Response and Sperm Storage-Related Genes Expression in Spermathecae of Bumblebee (Bombus terrestris) Queen.CSV by Yueqin Guo (11757317)

“…In total, the expression of 11, 069 and 10, 862 genes were identified in virgins and mated queens, respectively. We identified that 176 differentially expressed genes between virgin and mated queen spermathecae: 110 (62.5%) genes were upregulated, and 66 (37.5%) genes were downregulated in mated queens. …”