Let-7 and AGO1 mutually control each other in hypoxia. by Chen Zhao (225070)

“…(B) Let-7s that are in association with AGO1 are less prone to degradation, so a decrease in the binding strength of let-7 toward AGO1 causes more let-7 to be degraded. …”

Effect of MMP-2 activity inhibition on PARP-1 degradation. by Hiroyuki Kato (562772)

DataSheet1_Arctic stratosphere changes in the 21st century in the Earth system model SOCOLv4.pdf by Pavel Vargin (16809465)

“…In the late 21st century, the strengthening of the zonal mean meridional heat flux with a maximum of up to 20 K m/s (∼25%) in the upper stratosphere close to 70°N in January–February is obtained in the moderate scenario of GHG emission, while only a slight increase in this parameter over 50 N–60 N with the maximum up to 5 K m/s in the upper stratosphere and a decrease with the comparable values over the high latitudes is revealed in the severe GHG emission scenario. …”

<i>Ptprj in vitro</i> differentiation assays. by Chanel E. Smart (150987)

“…Error bars represent SD, n = 3. There was a statistically significant increase of <i>Ptprj</i> (p = 0.02) between 0 ng and 20 ng and a significant decrease of <i>Ptprj</i> (p = 0.02) between 20 ng and 50 ng. …”

Table_1_Harnessing the Potential of Native Microbial Communities for Bioremediation of Oil Spills in the Iberian Peninsula NW Coast.docx by Maria L. Bôto (10690125)

“…Only a few genera contributed for more than 50% of this genetic potential for aromatic compounds degradation in the enriched communities, namely Alcanivorax, Thalassospira, and Pseudomonas spp. …”

Table_3_Harnessing the Potential of Native Microbial Communities for Bioremediation of Oil Spills in the Iberian Peninsula NW Coast.docx by Maria L. Bôto (10690125)

“…Only a few genera contributed for more than 50% of this genetic potential for aromatic compounds degradation in the enriched communities, namely Alcanivorax, Thalassospira, and Pseudomonas spp. …”

<b>Effect of Marked Weight Loss on Adipose Tissue Biology in People with Obesity and Type 2 Diabetes</b> by Dmitri Samovski (305400)

“…</p><p dir="ltr"><b>Results: </b>Weight loss: <a href="" target="_blank">i) </a><a href="" target="_blank">decreased adipose tissue </a>expression of genes related to extracellular matrix remodeling; ii) decreased adipose tissue expression of SERPINE 1 which encodes plasminogen activator inhibitor-1 (PAI-1); iii) did not decrease adipose tissue immune cell content or expression of genes involved in inflammation; iv) decreased adipose tissue ceramide content; v) decreased plasma <a href="" target="_blank">PAI-1 </a>and leptin concentrations and increased plasma high-molecular weight (HMW) adiponectin; and vi) decreased plasma small extracellular vesicle (sEV) concentration and the sEV content of microRNAs proposed to inhibit insulin action, and completely reversed the inhibitory effect of plasma sEVs on insulin signaling in myotubes.…”

DataSheet1_Investigations of potential non-amino acid SNAT2 inhibitors.docx by Sebastian Jakobsen (17732745)

“…In contrast to the previous publication, MMTC showed no inhibition of SNAT2-mediated ³H-Gly uptake in PC-3 cells at a concentration of 1 or 5 μM, despite a published IC₅₀ of 0.8 µM. …”

Table_2_Harnessing the Potential of Native Microbial Communities for Bioremediation of Oil Spills in the Iberian Peninsula NW Coast.docx by Maria L. Bôto (10690125)

“…Only a few genera contributed for more than 50% of this genetic potential for aromatic compounds degradation in the enriched communities, namely Alcanivorax, Thalassospira, and Pseudomonas spp. …”

Tumor suppressor function of <i>RBMS3</i> in NPC cells. by Juan Chen (61123)

Effect of TRPV4-mediated activation of SK3 channels on membrane potential, Vm. by Jonathan Berrout (555482)

“…</b> Effect of TRPV4 activation with GSK101 (50 nM) leading to membrane hyperpolarization of Vm (decreased RFU), as expected for SK3 and BK activation. …”

MuSK patient IgG4 or IgG1-3 do not induce endocytosis of MuSK. by Inga Koneczny (481353)

“…(B) Staining was scored by two individuals as described in methods, and the scores were normalised to the score at 0 hours for each condition. A slight decrease in staining was observed for cells incubated at 37°C, and pre-fixed cells also showed this reduction. …”

Mechanically-sensitive afferents and presumed sympathetic efferents exhibit different twin pulse speeding and activity-dependent slowing during the repeated twin-pulse paradigm. by Matthias Ringkamp (253465)

“…Only data from twin pulses separated by 50 ms are included. Symbol coding same as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0009076#pone-0009076-g003" target="_blank">Fig. 3C</a>. …”

Exosin inhibits ExoS ADPRT activity. by Anthony Arnoldo (42511)

“…Diosmin, Everninic acid, 4296-1011 and E216-5303 directly modulate ExoS ADPRT enzymatic activity. IC₅₀ for each molecule is defined by the compound concentration required to decrease ExoS ADPRT activity by 50%. …”

IL-6 promotes RKIP and STAT 3 transcription and phosphorylation; <i>H. pylori</i> infection induces STAT3 transcription and phosphorylation. by Erika L. Moen (162280)

“…Densitometry was performed and for pRKIP expression, our results indicate a 1.8 fold incerase of pRKIP (average intensity 0.59 vs 1.051) in cells treated with 25 ng/ml IL-6 and a 1.35 fold increase (average intensity 0.59 vs 0.772) in cells treated with 50 ng/ml IL-6. …”

Data Sheet 1_The effect of COVID-19 and sex differences on natural killer cell cytotoxicity.zip by Arushi Dagar (22287460)

Salinity induces unique changes in lipid classes and fatty acids of the estuarine haptophyte <i>Diacronema vlkianum</i> by José-Pedro Cañavate (11771443)

“…Despite fatty acid changes, the unsaturation index did not vary with salinity, but nutritional value of <i>D. vlkianum</i> decreased at a salinity of 50 due to a lower presence of 20-C polyunsaturated fatty acids. …”

Video 2_The effect of COVID-19 and sex differences on natural killer cell cytotoxicity.avi by Arushi Dagar (22287460)

Igf signaling is required for contribution of<i>gata4:EGFP</i> positive cardiomyocytes to the regenerating area. by Ying Huang (53474)

“…<p><i>gata4:EGFP</i> fish were treated with the Igf1r inhibitor NVP-AEW541 from 2–14 dpa (n = 12) (B, D) and 7–10 dpa (n = 5) (F, H). DMSO was used as a control (14dpa: n = 10; 10 dpa: n = 6) (A, C, E, G). …”

MPI knockdown blocks FGFR1 signaling in SKMG-3 human glioma cells. by Aurélie Cazet (644004)

“…Asterisks (*) indicate a significant decrease of MPI expression after siRNA experiment compared to the expression in the control cells. …”