PDK1 inhibitor PF-5177624 decreased IGF-I induced AKT and p70S6K phosphorylation. by Sangita M. Baxi (123560)

iNOS deficiency ameliorated increased expression of atrogenes and decreased cross-sectional area in skeletal muscle of burned mice. by Harumasa Nakazawa (684211)

“…Muscle fiber cross-sectional area was significantly decreased by burn injury. iNOS deficiency partially prevented burn-induced decrease in muscle fiber cross-sectional area. …”

Role of Ser77 in ACER3 catalytic site. by Jae Kyo Yi (13570063)

THRα/β EC₅₀ values and selectivity of test compounds. by Xuan G. Luong (9761423)

SARS-CoV-2 induced lung inflammation is increased with IL-10 blockade and decreased with IFNγ blockade. by Christine E. Nelson (18946410)

Normal growth of <i>bipA</i>-deleted <i>E. coli</i> and <i>S</i>. Typhimurium at 37°C. by Eunsil Choi (8271039)

Subjects:

Ascorbic acid, total phenolics, proline, GB, hydrogen peroxide, MDA and total soluble proteins in the inflorescence of two cultivars of cauliflower (<i>Brassica oleracea</i> L.) pl... by Munifa Jabeen (12634746)

6:2 Chlorinated Polyfluoroalkyl Ether Sulfonate (F-53B) Induces Aging and Parkinson’s Disease-like Disorders in <i>C. elegans</i> at Low Concentrations by Hui Li (32376)

“…Here, we evaluated the aging and neurodegenerative effects of F-53B using the C. elegans model. After exposure to F-53B at 2, 10, and 50 ng/L, C. elegans showed an aging phenomenon as lipofuscin was significantly increased by 48.7–57.5% and locomotion, such as center point speed, was significantly decreased in all exposure groups. …”

6:2 Chlorinated Polyfluoroalkyl Ether Sulfonate (F-53B) Induces Aging and Parkinson’s Disease-like Disorders in <i>C. elegans</i> at Low Concentrations by Hui Li (32376)

“…Here, we evaluated the aging and neurodegenerative effects of F-53B using the C. elegans model. After exposure to F-53B at 2, 10, and 50 ng/L, C. elegans showed an aging phenomenon as lipofuscin was significantly increased by 48.7–57.5% and locomotion, such as center point speed, was significantly decreased in all exposure groups. …”

6:2 Chlorinated Polyfluoroalkyl Ether Sulfonate (F-53B) Induces Aging and Parkinson’s Disease-like Disorders in <i>C. elegans</i> at Low Concentrations by Hui Li (32376)

“…Here, we evaluated the aging and neurodegenerative effects of F-53B using the C. elegans model. After exposure to F-53B at 2, 10, and 50 ng/L, C. elegans showed an aging phenomenon as lipofuscin was significantly increased by 48.7–57.5% and locomotion, such as center point speed, was significantly decreased in all exposure groups. …”

6:2 Chlorinated Polyfluoroalkyl Ether Sulfonate (F-53B) Induces Aging and Parkinson’s Disease-like Disorders in <i>C. elegans</i> at Low Concentrations by Hui Li (32376)

“…Here, we evaluated the aging and neurodegenerative effects of F-53B using the C. elegans model. After exposure to F-53B at 2, 10, and 50 ng/L, C. elegans showed an aging phenomenon as lipofuscin was significantly increased by 48.7–57.5% and locomotion, such as center point speed, was significantly decreased in all exposure groups. …”

SmedCB shows a transient spike of protease activity following digestion and amputation, while chemical inhibition of both cathepsin B and L leads to a significant decrease in regen... by Louise S. Goupil (2922159)

“…The large upper band was quantified as SmedCB activity; five micrograms of total protein was used in each reaction with 10μM DCG-04. <b>(C)</b> Worms treated with SmedCB dsRNA did not show any significant defects in regeneration compared to untreated controls, but treatment with K11777 <b>(D)</b> showed a highly significant decrease in growth compared to vehicle worms. …”

Nemp1 KO mice display increased splenic stress erythropoiesis. by Didier Hodzic (132944)

HbA1c, BMI and Lipid levels of study participants (n = 382). by Habiba I. Ali (10451382)

Venn diagram of the distribution of the participants between the lowest quartiles of BMD according to DXA of the femoral neck (n = 42+50 = 92) and DXL of the calcaneus (n = 44+50 =... by Hans Lundin (800973)

Loss of Nemp1 leads to the expansion of erythroid progenitors and of early erythroblasts and to stress erythropoiesis. by Didier Hodzic (132944)

Identification of +TIPs required for MT plus-end targeting of dynein-dynactin in the <i>C</i>. <i>elegans</i> early embryo. by Daniel J. Barbosa (4288462)

“…Scale bar, 5 μm; insets, 2 μm. <b>(C)</b> Cortical confocal section in one-cell embryos co-expressing GFP::p50^DNC-2 and EBP-2::mKate2, showing that depletion of dynein intermediate chain^DYCI-1 or LIS-1 decreases dynactin levels at MT plus ends. …”

Nemp1 KO mice display splenomegaly, blood defects, and erythroid lineage expansion. by Didier Hodzic (132944)

Electron hits on the exposed cell array with 10⁴ cells for 100 keV incident photons for administered doses of (a) 10 mGy, (b) 20 mGy, (c) 50 mGy, (d) 100 mGy and (e) 500... by Mehrdad Shahmohammadi Beni (796228)

DnaK’s ATPase activity is stimulated by ribosomes and required to reduce protein synthesis. by Carissa Chan (18310140)