Prognosis for Hospitalized Patients with Systemic Lupus Erythematosus in China: 5-Year Update of the Jiangsu Cohort by Xuebing Feng (293563)

“…<div><p>Objective</p><p>To identify early signs associated with poor prognosis in Chinese patients with systemic lupus erythematosus (SLE) through a large population-based follow-up study.</p><p>Methods</p><p>Medical records of > 2,500 SLE patients that first hospitalized between 1999–2009 were collected from 26 centers across Jiangsu province, China, and entered into a database. …”

Effects of age of exercise onset on body composition across the lifespan. by Agnieszka Mika (306138)

TLR4 and NF-κB signaling pathway is required for the reduction of let-7b expression in response to <i>H.pylori</i> infection. by Gui-gen Teng (380044)

“…<p>(A) TKA-242 (1 uM) decreased the expression of TLR4 protein in AGS and GES-1 cells with <i>H.pylori</i>-infection. …”

SOCS3 regulated the fate of HSCs. by Yu-xiao Liu (146872)

“…Bar = 50 μm. (B) BFU-E and CFU-E derived from shSOCS3-1 CD34⁺ cells. …”

Mechanism of SFK phosphorylation and negative regulation of PKA in chicken sperm. by Chathura Priyadarshana (9635328)

“…<p>Sperm were incubated with 0–50 μM H-89 (PKA inhibitor), 25 μM KH7 (sAC inhibitor), 50 μM MDL (tmAC inhibitor), 0–250 μM PTP inhibitor, or EGTA-AM in the presence or absence of SKI606 and SU6656 and then subjected to immunodetection for p-SFK-Y416 or p-PKAs. …”

DELTA-1/NOTCH signaling in the caudal spinal cord of chick embryos. by Barbara Hämmerle (36261)

“…<p>A–A′. Confocal projection over 50 µm from a dorsal aspect of the prospective spinal cord at the level of the 12^th and 13^th somites counted from rostral of a HH13 chick embryo that was electroporated with NICD at stage HH10 when that region was part of the PNTZ. …”

Real-world weight changes in people with HIV-1 at risk of weight gain (female, Black or Hispanic) switching from integrase strand transfer inhibitors: supplementary figure by Prina Donga (8899571)

Platelet thrombus formation on immobilized VWF in the presence of HbS. by Gowtham K. Annarapu (2622811)

“…Further the thrombus was decreased in presence of 5 μM AA1-50 <b>(B3)</b> but not in presence of control peptide <b>(B4)</b>.…”

Serine 26 in the PomB Subunit of the Flagellar Motor Is Essential for Hypermotility of <i>Vibrio cholerae</i> by Petra Halang (561390)

Sensitivity of the long-term reduction in microfilarial load in individuals under 20 years of age to the assumed rate of decay of vaccine efficacy. by Hugo C. Turner (407442)

“…<p>The mean duration of vaccine prophylactic (against incoming L3 larvae) and therapeutic (against microfilariae) activity is 1/the rate of decay (i.e. 5, 10, 20 and 50 years). …”

Insulin effects on taste cell generation in organoids. by Shingo Takai (7853843)

“…<p>(A-D) Representative confocal images of taste bud organoids prepared from mouse circumvallate (CV) tissue grown in conditioned medium (CM) with varying insulin concentrations: (A) 0 nM, (B) 1 nM, (C) 10 nM, and (D) 50 nM. …”

Supporting information data. by Miriam Serrano Soliva (19485617)

Linagliptin does not increase catalase and MnSOD mRNA but trends to increase catalase protein level while significantly enhancing MnSOD protein level in G6PD^- mouse kidn... by Netanya Y. Spencer (5488931)

Metabolic and neuronal origins of the intrinsic flavoprotein signal response. by Cedric R. Uytingco (3371243)

“…<p><b>(A)</b> Mean flavoprotein signal amplitude of the light phase (black) and dark phase (gray) from the GL (solid) and EPL (dash) upon treatment with 10 μM DPI. …”

Mu opioid agonist-induced [³⁵S]-GTPγS binding is comparable on spinal cord membrane preparation from mu-cKO and mu^fl mice. by Raphaël Weibel (458030)

“…[³⁵S]-GTPγS binding was absent on spinal cord membranes from mu-KO mice, and was decreased by half with a 50%-50% mix of membranes from mu^fl and mu-KO animals, containing half mu receptors as compared to mu^fl membranes, indicating that this assay allows to detect reduced receptor expression. …”

Influence of COS on the activation of NF-κB in retina and RGC-5 cells. by I-Mo Fang (470460)

“…(B) COS decreased the amount of activated NF-κB translocated into nucleus in PQ-stimulated RGC-5 in a time-dependent and (C) dose-dependent manner. …”

Supplementary Material for: Comparison of urinary protein/creatinine ratio as an alternative to 24-hour proteinuria in Lupus Nephritis: TUNARI study by Gutiérrez-Peredo G.B. (16439571)

“…Results: We compared 112 samples of 75 patients with LN, with a mean age of 34.5 ± 11.8 years. …”

Organ level model. by Shayoni Ray (179927)

“…<p>An organ-level simulation containing three ideally localized clefts is shown at (a) 0 MCS and (b) 1500 MCS (Scale = 50 µm). The results were quantified with (c) cleft depth and (d) spanning angle. …”

Cytotoxicity of candidate agents to cholangiocarcinoma cells. by Chiara Braconi (235041)

“…All three compounds decreased cell viability in a concentration-dependent manner, with an IC50 for felodipine of 26±5 µM, nitrendipine, 44±10 µM and nifedipine, 15±4 µM. …”

Data_Sheet_1_The Role of Sustained Photoprotective Non-photochemical Quenching in Low Temperature and High Light Acclimation in the Bloom-Forming Arctic Diatom Thalassiosira gravid... by Thomas Lacour (5877947)

“…T. gravida growth remained possible under a wide range of irradiances but photosynthetic plasticity was higher at moderately low light (up to ~50 μmol photons m⁻² s⁻¹), nevertheless corresponding to the mean in situ conditions under which it predominates, i.e., underneath the spring thin-ice punctuated with melting ponds. …”