Data Sheet 1_Global burden of ischemic heart disease attributable to ambient and household PM2.5 exposure: a comprehensive analysis (1990–2021) from socioeconomics perspective.pdf... by Chenran Zhang (4443106)

“…ASMR and ASDR of IHD exhibited a nonlinear association with SDI. PM_2.5 demonstrated positive correlation in regions with SDI < 0.49, and negative correlation in regions with SDI > 0.623. …”

Effects of vinculin and Rab5 knockdown on cellular uptake. by Makoto Hagiwara (513898)

“…<p>(A) siRNAs for vinculin were transfected into HeLa cells, and cell lysates were assayed by western blotting using anti-vinculin, anti-Rab5, and anti-GAPDH antibodies (internal control). …”

Schematic overview of molecular processes altered during disease progression in the SN of PD, identified using transcriptome analysis. by Anke A. Dijkstra (756877)

“…In Braak alpha-synuclein 5 and 6 compared to controls, severe cell loss and alpha-synuclein aggregation is observed [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0128651#pone.0128651.ref041" target="_blank">41</a>]. …”

Data_Sheet_2_Efficacy and safety of endothelin receptor antagonists, phosphodiesterase type 5 Inhibitors, and prostaglandins in pediatric pulmonary arterial hypertension: A network... by Fen Cao (4496014)

“…</p>Conclusions<p>ERAs were more effective than ProsA in shortening the duration of mechanical ventilation, while ProsA were better for shortening the duration of mechanical ventilation and ICU stay than PDE-5i. …”

Data_Sheet_1_Efficacy and safety of endothelin receptor antagonists, phosphodiesterase type 5 Inhibitors, and prostaglandins in pediatric pulmonary arterial hypertension: A network... by Fen Cao (4496014)

“…</p>Conclusions<p>ERAs were more effective than ProsA in shortening the duration of mechanical ventilation, while ProsA were better for shortening the duration of mechanical ventilation and ICU stay than PDE-5i. …”

Data_Sheet_3_Efficacy and safety of endothelin receptor antagonists, phosphodiesterase type 5 Inhibitors, and prostaglandins in pediatric pulmonary arterial hypertension: A network... by Fen Cao (4496014)

“…</p>Conclusions<p>ERAs were more effective than ProsA in shortening the duration of mechanical ventilation, while ProsA were better for shortening the duration of mechanical ventilation and ICU stay than PDE-5i. …”

Data_Sheet_4_Efficacy and safety of endothelin receptor antagonists, phosphodiesterase type 5 Inhibitors, and prostaglandins in pediatric pulmonary arterial hypertension: A network... by Fen Cao (4496014)

“…</p>Conclusions<p>ERAs were more effective than ProsA in shortening the duration of mechanical ventilation, while ProsA were better for shortening the duration of mechanical ventilation and ICU stay than PDE-5i. …”

Defects in the conduction of somatosensory evoked potentials of median and tibial nerves in a healthy child and in H-ABC patient. by Jose R. Eguibar (8563227)

Kinetics of parasitaemia (asexual stages only, black dots) and gametocytaemia (stages 1–5; black squares) by microscopic observation, represented as a percentage of total erythrocy... by Joël Lelièvre (2196628)

“…From that time onwards, a rapid decrease occurred leading to a parasitaemia (asexual stages) close to zero on day 17. …”

Using a coupled dynamic factor – random forest analysis (DFRFA) to reveal drivers of spatiotemporal heterogeneity in the semi-arid regions of southern Africa - Fig 5 by Jane Southworth (452365)

Using a Bayesian network to understand the importance of coastal storms and undeveloped landscapes for the creation and maintenance of early successional habitat by Sara L. Zeigler (497021)

“…We found that Hurricane Sandy increased piping plover habitat by 9 to 300% at 4 of 5 study sites but that one site saw a decrease in habitat by 27%. …”

Functional validation of a miRNA-34a-TREM2–3’UTR interaction. by Surjyadipta Bhattacharjee (3181674)

“…<p><b>(A)</b> ribonucleotide sequence of the 299 nt TREM2-mRNA-3’-UTR is shown in the 5’-3’ direction; the 22 nt miRNA-34a-TREM2 3’UTR complementarity-interaction region is indicated by a black underline and the 8 nt TREM2-mRNA-3’-UTR seed sequence <b>5’-ACACUGCU-3’</b> is overlaid in yellow; a single arrowhead indicates the 5’ end of a poly A+ tail in the TREM2 mRNA (22 ‘A’ nt shown; the length of this poly A+ tail is variable); TREM2 mRNA sequence derived from NM_018965; TREM2 transcript is the major X1 variant (see also <a href="http://switchdb.switchgeargenomics.com/productinfo/id_801321/" target="_blank">http://switchdb.switchgeargenomics.com/productinfo/id_801321/</a>) (<b><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0150211#pone.0150211.g003" target="_blank">Fig 3</a></b>); <b>(B)</b> TREM2-mRNA-3’UTR expression vector luciferase reporter assay (pLightSwitch-3’UTR; Cat#S801178; Switchgear Genomics, Palo Alto CA); in this vector, the entire 299 nucleotide TREM2 3’UTR was ligated into the unique Nhe1-Xho1 site; <b>(C)</b> control C8B4 murine microglial cells, 1 week in culture; phase contrast bright field microscopy 20x; C8B4 cells transfected with the TREM2-mRNA-3’UTR expression vector luciferase reporter were treated exogenously with miRNA-34a, a scrambled control miRNA-34a (miRNA-sc) or control miRNA-183; see references and text for further details [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0150211#pone.0150211.ref018" target="_blank">18</a>,<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0150211#pone.0150211.ref019" target="_blank">19</a>]; <b>(D)</b> compared to control, C8B4 cells transfected with a scrambled (<b>sc</b>) control pLightSwitch-3’UTR vector, the TREM2-mRNA-3‘UTR vector exhibited decreased luciferase signal to a mean of 0.16-fold of controls in the presence of miRNA-34a; this same vector exhibited no change in the presence of the control miRNA-34a-sc or miRNA-183; for each experiment (using different batches of MG cells) a control luciferase signal was generated and included separate appropriate controls with each analysis; in addition a control vector β-actin-3’UTR showed no significant effects on the relative luciferase signal yield after treatment with either miRNA-183 or miRNA-34a (data not shown); dashed horizontal line set to 1.0 for ease of comparison; N = 5; *<i>p</i><0.001 (ANOVA). …”

Relative risk of all-cause mortality following SARS-CoV-2 infection in people with preexisting mental disorders. by Tomáš Formánek (19139519)

Relative risk of death with COVID-19 following SARS-CoV-2 infection in people with preexisting mental disorders. by Tomáš Formánek (19139519)

Time-dependent variance of the probability fluxes. by Vladimir A. Andryushchenko (4662829)

Subfigures 4(a), 4(c), 4(e) and 4(g) present the uptrends duration distributions and subfigures 4(b), 4(d), 4(f) and 4(h) correspond to downtrends duration distributions. by Héctor Raúl Olivares-Sánchez (13014866)

Average grass leaf nitrogen (N), phosphorus (P), increaser (I) or decreaser (D) species and palatability (Palat.code: 0 =  not palatable, 1 =  moderately palatable, 2 =  highly pal... by Anna Christina Treydte (498202)

Lignin Extraction and Condensation as a Function of Temperature, Residence Time, and Solvent System in Flow-through Reactors by David G. Brandner (21909547)

Spatial structure of precipitation anomaly trend (left column) and trend difference relating to changes in precipitation intensity distribution (right column) from ((a), (e)) GPCP,... by Chunlei Liu (57542)

“…</strong> Spatial structure of precipitation anomaly trend (left column) and trend difference relating to changes in precipitation intensity distribution (right column) from ((a), (e)) GPCP, ((b), (f)) AMIP5, ((c), (g)) CMIP historical and ((d), (h)) RCP 4.5 data sets. …”

Distinct requirements for ROCK-1/2 expression in phase 1 and phase 2 leak. by Paul R. Clark (714064)