Selectivity of PRMT5 inhibition with C220. by Shelby L. Sloan (10803222)

“…For all cell lines, effects of PRMT5 inhibition with C220 treatment on biomarkers of PRMT5 activity shows a dose-dependent decrease in global marks of symmetric di-methylarginine (SDMA) and symmetric di-methylation of histone H4 arginine-3 (H4R3me2s) with a minimal effect to PRMT5 or global asymmetric di-methylarginine (ADMA). …”

MicroRNA-139-5p acts as a suppressor gene for depression by targeting nuclear receptor subfamily 3, group C, member 1 by Bing Su (51332)

“…However, its function in depression is unclear. Therefore, we investigated the function of miR-139-5p in depression. …”

Image_5_Cardioprotective Effects and Possible Mechanisms of Luteolin for Myocardial Ischemia-Reperfusion Injury: A Systematic Review and Meta-Analysis of Preclinical Evidence.TIF by Qinyuan Pan (11589910)

Table_1_Previous Use of Anti-Vascular Endothelial Growth Factor Receptor Agents Decreases Efficacy of Fruquintinib in Metastatic Colorectal Cancer Refractory to Standard Therapies.... by Lei Wang (6656)

“…Progression-free survival (PFS) and overall survival (OS) were assessed by a Kaplan-Meier analysis and log-rank test. A Cox regression model was performed to identify independent prognostic factors.…”

Propofol increased the number of the hippocampal pyramidal neurons and decreased the expression of the LC3-II protein and the number of lysosomes and autophagosomes in the ischemic... by Derong Cui (326839)

“…Statistical analyses were performed using a one-way ANOVA. **<i>p</i> < 0.01 vs. control group; ^##<i>p</i> < 0.01 vs. …”

Line graph of estimated probability of silicosis in increasing categories of 0.5 mg/m3-years at varying associations of cumulative RCS exposure and silicosis. by Patrick Howlett (2612374)

Loss of <i>FGR41</i> attenuates virulence in a host immune system dependent manner. by Andrew S. Wagner (11331477)

YorkU.forest.Oct5-2016 by Amrit Virdi (3130035)

“…This was our first week of sampling for these specific data sets. There will be a total of 3 censuses. </p> <p><b>Calender.date:</b> Represents the date we conducted the sampling. …”

Presentation_1_Phosphodiesterase Type 5 (PDE5) Inhibitors Sensitize Topoisomerase II Inhibitors in Killing Prostate Cancer Through PDE5-Independent Impairment of HR and NHEJ DNA Re... by Jo-Fan Chang (6237680)

“…In conclusion, the data suggest that sildenafil and vardenafil induce PDE5-independent apoptotic sensitization to doxorubicin (or other topoisomerase II inhibitors) through impairment of both HR and NHEJ repair systems that are evident by a decrease of nuclear Rad51 levels and their foci formation in the nucleus, and an inhibition of Ku80 DNA end-binding capability. …”

PM exposure affects small airways to a greater degree in WT compared to Ager^-/- mice. by Erin J. Caraher (4445902)

“…<p>(A) WT-PM mice had significantly elevated tissue resistance at 1Hz p<0.001 (*). …”

The expression level of hub genes in EOC tissues at different stages. by Ting Gui (304563)

“…According to the result, there were significant variations in the expression levels of CDC45, CDCA5, KIF4A, and ESPL1 (a-d). The overall trends indicated that the expression of these four genes decreased gradually with the continuous progression of OC.…”

Hepcidin decreased DMT1 and FPN at mRNA and protein level but did not alter most calcium transporter and calcium binding protein expression at mRNA level. by Supathra Phoaubon (11559357)

A representative case of a 68-year-old man with local tumor progression. by Yuan-Mao Lin (6934361)

“…<p>A 68-year-old man (body weight, 70.4 kg; BMI, 24.1 kg/m²) underwent multiphasic hepatic CT with dual source DECT at half reduced contrast medium dose. …”

Outcome measures recorded in the trade-off test. Willingness to move away from the two companions kept in a pen adjacent to the test area in trade-off with grain was measured.... by Sarah Kappel (4437403)

“…Willingness to move away from the two companions kept in a pen adjacent to the test area in trade-off with grain was measured. …”

Proteome profile of SupT1 cells after Nef Transfection. by Reshu Saxena (130830)

Spatiotemporal Changes of Urban Growth and Particulate Matter 2.5 Concentrations in Sylhet Sadar Upazila: A regional study using GIS RS techniques by Mizanur Rahman (18859573)

“…<p dir="ltr">Despite being one of the fastest growing developing countries, Bangladesh is consistently ranked among the most air countries in the world The adverse effects of air pollution on the economy and public health are significant, yet efforts to combat it have been minimal Unplanned urbanisation and industrialization are key contributors to air pollution, particularly particulate matter This study employed the Support Vector Machine ( to identify different land use types and utilised ANOVA tests to examine the variations in land cover categories over time The findings reveal a substantial increase of approximately 28 42 in built up areas, alongside a decrease of 39 53 in mixed forest cover between 2001 and 2019 in Sylhet Concurrently, PM2.5 concentrations have risen from 49.00 µg/m³ to 57.00 µg/m³ The study concludes that the expansion of built up and barren lands contributes to the escalation of PM2.5 levels, whereas forested areas and water bodies are associated with reductions in PM2.5 concentrations</p>…”

Weighted co-abundance analysis identified a subnetwork of bacteria significantly associated with FMT. by Arnon Gal (3150036)

“…<p>A weighted co-abundance network was generated to identify subnetworks (modules) of taxa associated with FMT. …”

In Vitro Anticancer Activity of <i>cis</i>-Diammineplatinum(II) Complexes with β-Diketonate Leaving Group Ligands by Justin J. Wilson (1980262)

“…Five cationic platinum­(II) complexes of general formula, [Pt­(NH₃)₂(β-diketonate)]­X are reported, where X is a noncoordinating anion and β-diketonate = acetylacetonate (acac), 1,1,1,-trifluoroacetylacetonate (tfac), benzoylacetonate (bzac), 4,4,4-trifluorobenzoylacetonate (tfbz), or dibenzoylmethide (dbm), corresponding, respectively, to complexes <b>1</b>–<b>5</b>. …”

Effects of soil microorganisms application to substrates of different organic matter content on Quantum Yield (QY) (A) and Normalized Difference Vegetation Index (NDVI) (B) in toma... by Robert Pokluda (8871407)

End Stage Renal Disease Predicts Increased Risk of Death in First Degree Relatives in the Norwegian Population by Rannveig Skrunes (3339708)

“…Excluding known hereditary renal disease, aHR decreased to 1.12 (1.09–1.15). Cardiovascular death aHR was 1.15 (1.10–1.21), of which cerebrovascular death 1.34 (1.22–1.50). aHR for death due to non-hereditary renal/ureteric disease was 2.29 (1.81–2.91) with renal failure 1.80 (1.26–2.56) and glomerular disease 5.69 (3.88–8.34) as main contributors. …”