Evaluating the Potential of Ozone Microbubbles for Inactivation of Tulane Virus, a Human Norovirus Surrogate by Bozhong Guan (18598178)

“…After 2, 10, and 20 min postgeneration, the ozone concentration of microbubbles naturally decreased from 4 ppm to 3.2 ± 0.2, 2.26 ± 0.19, and 1.49 ± 0.23 ppm and resulted in 1.43 ± 0.44, 0.88 ± 0.5, and 0.68 ± 0.53 log₁₀ viral reductions, respectively, while the ozone concentration of aqueous ozone decreased from 4 ppm to 2.52 ± 0.07, 0.43 ± 0.05, and 0.09 ± 0.01 ppm and produced 0.8 ± 0.28, 0.29 ± 0.41, and 0.16 ± 0.21 log₁₀ reductions against Tulane virus, respectively (<i>p</i> = 0.0526), suggesting that structuring of ozone in the bubbles over the applied treatment conditions did not have a significant effect, though future study with continuous generation of ozone microbubbles is needed.…”

A visual summary of the key study findings. by Joachim Worthington (8394213)

“…Modelling was used to estimate short- and long-term effects on colorectal cancer incidence and mortality, including ongoing impact of patient backlogs. A hypothetical mitigation strategy was simulated, with diagnostic and treatment capacities increased by 5% from 2022 to address backlogs. …”

A Novel Type of PSMA-Targeting Ligands via β‑Branched Aromatic α‑Amino Acid Modification, Bearing Enhanced Tumor Targeting and Reduced Renal Toxicity by Zong-Xiao Liu (22177765)

A Novel Type of PSMA-Targeting Ligands via β‑Branched Aromatic α‑Amino Acid Modification, Bearing Enhanced Tumor Targeting and Reduced Renal Toxicity by Zong-Xiao Liu (22177765)

Small Open Reading Frames, Non-Coding RNAs and Repetitive Elements in <i>Bradyrhizobium japonicum</i> USDA 110 by Julia Hahn (3279486)

“…We found that BjsR1 and BjsR3 have homologs outside the genus <i>Bradyrhizobium</i>, and BjsR5, BjsR6, BjsR7, and BjsR10 have up to four imperfect copies in <i>Bradyrhizobium</i> genomes. …”

Characterization of Cross-Linked Porous Gelatin Carriers and Their Interaction with Corneal Endothelium: Biopolymer Concentration Effect by Jui-Yang Lai (277828)

“…The aim of this study was to further investigate the effects of biopolymer concentrations (5–15 wt%) on the characteristic and safety of hydrogel discs fabricated by a simple stirring process combined with freeze-drying method. …”

Example IRT images from a meloxicam-treated (a) and placebo-treated control piglet (b) after castration. by Jessica L. Bates (667627)

Persistent HIV-1 suppression after deferiprone cessation in treatment-naive HIV-infected subjects. by Deepti Saxena (462177)

“…<p>Discontinuation trial design (DTD) is used to analyze long-term rebound following HIV-1 RNA—based segregation into a ‘Decrease’ and a ‘No decrease’ cohort, defined by viral load post-drug on Day 7 relative to viral load pre-drug on Day 1. …”

Impaired fibronectin and fibrinogen-cleaving activities of the E143A and H146A Zmp1 mutants. by Valeria Cafardi (490077)

“…(<b>C</b>) Decreased ability of E143A and H146A Zmp1 mutants to cleave fibronectin. 1 µM fibronectin from human plasma was incubated for 24 h at 37°C with no Zmp1 (control) or with 7.7 µM of wild type (WT), E143A or H146A Zmp1 in the presence of 0.5 mM ZnCl₂. 1 µg of fibronectin was analyzed by SDS-PAGE and Coomassie-blue staining. …”

Mixed Lineage Leukemia 5 (MLL5) Protein Stability Is Cooperatively Regulated by O-GlcNac Transferase (OGT) and Ubiquitin Specific Protease 7 (USP7) by Xiaodan Ding (838408)

“…Depletion of OGT in cells led to a decrease in the MLL5 protein level through ubiquitin/proteasome-dependent proteolytic degradation, whereas ectopic expression of OGT protein suppressed MLL5 ubiquitylation. …”

Table_1_Effects of Early Changes in Blood Pressure During Intravenous Thrombolysis on the Prognosis of Acute Ischemic Stroke Patients.docx by Zhong-Xiu Wang (9729359)

“…Patients with a lower baseline National Institute of Health Stroke Scale (NIHSS) score (8.25 ± 5.57 vs. 13.51 ± 7.42, P < 0.001), a higher Alberta Stroke Program Early CT Score (ASPECTS; 8.65 ± 1.82 vs. 8.13 ± 2.00, P = 0.005), decreased BP during thrombolysis (69.4% vs. 59.8%, P = 0.037), and steady BP (SD < 10 mmHg) were more likely to have a favorable outcome (73.9% vs. 60.6%, P = 0.019). …”

Image5_Transferability of the PRS estimates for height and BMI obtained from the European ethnic groups to the Western Russian populations.JPEG by E. A. Albert (14430201)

Cluster-centroid profile analysis of the right V1 (cluster II) in healthy controls (blue) and patients with Leber's Hereditary Optic Neuropathy (LHON) (red). by Maria A. Rocca (356197)

“…In addition, compared to controls, the right V1 of LHON patients had an increased structural connectivity with the temporal occipital fusiform cortex and a decreased structural connectivity with the lateral occipital cortex and the occipital fusiform gyrus. …”

Table_5_A Specific IL6 Polymorphic Genotype Modulates the Risk of Trypanosoma cruzi Parasitemia While IL18, IL17A, and IL1B Variant Profiles and HIV Infection Protect Against Cardi... by Alexandra Gomes dos Santos (9449003)

Locations of DRM peaks and misregulation of DRM target genes. by Paul D. Goetsch (4559587)

Under-five mortality in the Rongo Sub-County of Migori County, Kenya: Experience of the Lwala Community Alliance 2007-2017 with evidence from a cross-sectional survey by Joseph R. Starnes (5729039)

“…</p><p>Conclusions</p><p>There was a significant decrease in under-five mortality before and after the presence of the Lwala Community Alliance. …”

Sensitivity of <i>B</i>. <i>subtilis</i> Rho⁺ to fatty acid starvation and heat stress. by Vladimir Bidnenko (4258573)

<i>B</i>. <i>subtilis</i> Rho⁺ exhibits competence–negative phenotype. by Vladimir Bidnenko (4258573)

Supplementary Material for: Monoclonal Antibodies against the Human Somatostatin Receptor Subtypes 1–5: Development and Immunohistochemical Application in Neuroendocrine Tumors by Schmid H.A. (4126171)

“…Immunoreactivity of sstr1, sstr2a and sstr4 tended to decrease as tumor aggressiveness increased. sstr5 showed an opposite pattern, with higher staining in well-differentiated carcinomas compared with well-differentiated tumors. sstr5 immunoreactivity was correlated with the presence of metastases and angioinvasion, suggesting a possible association with more aggressive behavior. …”

Efflux potentiation by 4′,5′-<i>O</i>-dicaffeoylquinic acid in <i>S. aureus</i> (A), <i>E. faecalis</i> (B). by Yiannis C. Fiamegos (225675)

“…Cells were loaded with berberine at a concentration of 100 µg/ml, and then resuspended in buffer in the absence or presence of 4′,5′-<i>O</i>DCQA, at the same final concentrations used for the MIC determinations.…”