Showing 321 - 340 results of 30,666 for search '(( 50 ((nn decrease) OR (we decrease)) ) OR ( 10 ((nm decrease) OR (mean decrease)) ))', query time: 0.52s Refine Results
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    Selective Inhibitors of Janus Kinase 3 Modify Responses to Lipopolysaccharides by Increasing the Interleukin-10-to-Tumor Necrosis Factor α Ratio by Julian Laux (13047767)

    Published 2023
    “…JAK1 is required for IL-10 receptor signaling, which suggests that, at exposure above the IC<sub>50</sub> (55 nM for tofacitinib on JAK1), there is less feedback control of TNFα levels. …”
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