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621
Barriers and Motivators of Appropriate Antibiotic Prescription at PHCC in Qatar: Perspective of Physicians and Pharmacists
Published 2020“…Antimicrobial resistance (AMR) is a serious public health problem of global concern. …”
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622
Barriers and motivators of appropriate antibiotic prescription at PHCC in Qatar: perspective of physicians and pharmacists
Published 2020“…Antimicrobial resistance (AMR) is a serious public health problem of global concern. …”
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623
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624
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625
Low electro-synthesis potentials improve permselectivity of polymerized natural phenols in biosensor applications
Published 2017“…The natural phenol-coated electrodes were stable and responsive throughout 14 days. A biosensor prototype based on acetylcholine esterase and choline oxidase was electro-coated with poly-magnolol in order to evaluate the interference-rejecting properties of the electrosynthesized film in an amperometric biosensor; a moderate decrease in ascorbic acid rejection was observed during in vitro calibration of biosensors.…”
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626
Molecular and Structural Changes in Induced-Brain Stroke Tissue Using FTIR Imaging Spectroscopy, Scanning Electron and Atomic Force Microscopy
Published 2016“…All the samples were viewed with a FEI Quanta 200, USA scanning electron microscope at 10 kV. …”
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627
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628
Synthesis of silica supported ni and cu catalyst for carbon dioxide methanation reaction
Published 2019“…In this study we investigate the synthesis of nickel and copper catalyst supported on silica for CO2 conversion to methane. …”
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629
Design and analysis of PV fed high-voltage gain DC-DC converter using PI and NN controllers
Published 2022“…When the converter switch comes under active state two capacitors are discharged in series, similarly when the converter switch under inactive state those two capacitors are charged in parallel through the coupled inductor (CI) energy so, to get a high voltage at the converter output side. To reuse the leakage-inductor (LI) energy of the CI with the help of a passive clamp circuit for reducing the voltage stress across the switch, similarly switch has less resistance so conduction losses also decreased. …”
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630
STRUCTURAL AND FUNCTIONAL APPROACHES TOWARD ACTIVITY RESTORATION OF NOVEL CYSTATHIONINE BETA-SYNTHASE MUTATIONS
Published 2024“…This study investigates the impact of five pathogenic CBS missense mutations [c.1006C>T (p.R336C), c.689T>A (p.L230Q), 215A>T (p.K72I), c.707C>A (p.T236N), and c.457G>A (p.G153R)] identified in homocystinuria patients and appeared to be resistant to pyridoxine treatment on the biochemical and biophysical properties of CBS protein. …”
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631
A computational model to predict the structural and functional consequences of missense mutations in O6-methylguanine DNA methyltransferase
Published 2019“…Considering true positives, true negatives, false positives, and false negatives, three mutations (Y114E, R128G, and C145A) showed "loss of DNA repair activity," and were analyzed further using molecular dynamics simulations (MDS) using GROMACS for 50ns. MDS run showed that the C145A mutant demonstrated higher structural deviation, decreased compactness, and the binding patterns. …”
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632
Glycine and Folate Ameliorate Models of Congenital Sideroblastic Anemia
Published 2016“…Sideroblastic anemias are acquired or inherited anemias that result in a decreased ability to synthesize hemoglobin in red blood cells and result in the presence of iron deposits in the mitochondria of red blood cell precursors. …”
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633
Calmodulin Mutations Associated with Congenital Cardiac Disease Display Novel Biophysical and Biochemical Characteristics
Published 2018“…In contrast, in the presence of Ca2+, there was a significant decrease in the stability of the five proteins following the order CaMWT> CaMN98I > CaMD132E > CaMQ136P > CaMD134H. …”
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Driver Drowsiness Detection Study using Heart Rate Variability analysis in Virtual Reality Environment
Published 2018“…The LF/HF ratio reflects the differences between awake and drowsy states while the ratio was decreasing gradually from the awake state to drowsy state [5-6].Method A portable wireless BioRadio (Fig.2 A) (Great Lakes NeuroTechnologies, Inc.) …”
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636
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637
Investigating the utilization of healthcare services to manage respiratory tract infections (RTIs) among Qatari patients attended selected primary healthcare centers in Qatar
Published 2018“…We have found no difference in the month-to-month rates of RTI-related GP visits (per 1000 total visits) over the study period (non-significant decreasing trend). However, there was a significant decreasing trend in the monthly rates of antibiotics consumption and an increasing trend in the tests/investigations done but there was no clear increasing or decreasing trend in the monthly rates of other medications use. …”
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638
Biochemical and structural impact of two novel missense mutations in cystathionine β-synthase gene associated with homocystinuria
Published 2024“…We observed that the disease-associated K72I genetic variant had no apparent effects on the spectroscopic and catalytic properties of the full-length enzyme. …”
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Salvia fruticosa Induces Vasorelaxation in Rat Isolated Thoracic Aorta: Role of the PI3K/Akt/eNOS/NO/cGMP Signaling Pathway
Published 2017“…Prior exposure to PI3K inhibitors, wortmannin (0.1 µM) or LY294002 (10 µM), decreased cGMP accumulation and attenuated the SF-induced vasorelaxation by approximately 50% (Rmax). …”
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