Utilizing CMP-Sialic Acid Analogs to Unravel <i>Neisseria gonorrhoeae</i> Lipooligosaccharide-Mediated Complement Resistance and Design Novel Therapeutics by Sunita Gulati (451977)

“…<div><p><i>Neisseria gonorrhoeae</i> deploys a novel immune evasion strategy wherein the lacto-N-neotetraose (LNnT) structure of lipooligosaccharide (LOS) is capped by the bacterial sialyltransferase, using host cytidine-5’-monophosphate (CMP)-activated forms of the nine-carbon nonulosonate (NulO) sugar <i>N</i>-acetyl-neuraminic acid (Neu5Ac), a sialic acid (Sia) abundant in humans. …”

Figure S6. Treatment with a CCR4 antagonist decreases CCR4+ Tregs and increases T cell/Treg ratios in murine glioma. from CCL2 Produced by the Glioma Microenvironment Is Essential... by Alan L. Chang (14250716)

Data_Sheet_5_Outcome and Complications of MR Guided Focused Ultrasound for Essential Tremor: A Systematic Review and Meta-Analysis.docx by Mohit Agrawal (10761501)

“…Analysis of other complications further revealed a decreasing trend on follow up.</p>…”

A function blocking anti-mouse integrin α5β1 antibody inhibits angiogenesis and impedes tumor growth -4 by Vinay Bhaskar (85020)

“…<p><b>Copyright information:</b></p><p>Taken from "A function blocking anti-mouse integrin α5β1 antibody inhibits angiogenesis and impedes tumor growth "</p><p>http://www.translational-medicine.com/content/5/1/61</p><p>Journal of Translational Medicine 2007;5():61-61.…”

The amplitude of correlation coefficients decreases under subsampling, whereas the intrinsic timescale <i>τ</i> and the branching parameter <i>m</i> (characterized by the slope of... by F. P. Spitzner (10725103)

The AzEvC10 mutant induces iron dysregulation, oxidative stress, and ferroptosis in macrophages. by Mylene Vaillancourt (7409486)

Drug repositioning against COVID-19: a first line treatment by Nousheen Bibi (446289)

“…Further through molecular dynamics simulation, critical conformational changes in the target protein molecules were revealed upon drug binding which illustrates the favorable binding conformations of antiviral drugs against SARS-CoV-2 target proteins. The resulting drugs from the present study in combination and in cocktails from the arsenal of existing drugs could reduce the translational distance and could offer substantial clinical benefit to decrease the burden of COVID-19 illness. …”

Data Sheet 1_SARS-CoV-2 Nsp7 plays a role in cognitive dysfunction by impairing synaptic plasticity.docx by Jiazheng Guo (14799721)

“…Initially, we confirmed a reduction in the level of synaptic proteins in SH-SY5Y neurons following SARS-CoV-2 infection. …”

Population dynamics of <i>Killer-Rescue</i>/Cargo, ClvR and split^50cM <i>ClvR</i> for elements with different fitness costs, and introduction percentages. by Georg Oberhofer (3401438)

RhoA GTPase positively and transcriptionally controls CD70 membrane and global expression. by Christine Pich (367328)

Household Water Chlorination Reduces Incidence of Diarrhea among Under-Five Children in Rural Ethiopia: A Cluster Randomized Controlled Trial by Bezatu Mengistie (234272)

“…<div><p>Background</p><p>Household water treatment has been advocated as a means of decreasing the burden of diarrheal diseases among young children in areas where piped and treated water is not available. …”

Fast-slow decomposition of the model dynamics when the V0_V excitatory pathways are deleted. by Yaroslav I. Molkov (542831)

“…LF-RF<b>"</b> diagram in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1004270#pcbi.1004270.g005" target="_blank">Fig 5B</a>, the left knees of the red nullclines are at higher <i>h</i>_<i>NaP</i> values than the left knee of the unperturbed (gray) <i>V</i>-nullcline (i.e. in the yellow area) thus making it possible for the LF to reach the yellow area during the active phase of the RF (i.e. by climbing up in the red band). …”

Fig 4 - by Chengyu Wu (640314)

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The combination of indisulam and melphalan inhibits MM cell proliferation and induces cell apoptosis and DNA damage. by Chengyu Wu (640314)

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Fig 1 - by Chengyu Wu (640314)

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Combinatorial treatment delays MM growth in vivo. by Chengyu Wu (640314)

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Supporting Role for GTPase Rab27a in Hepatitis C Virus RNA Replication through a Novel miR-122-Mediated Effect by Tzu-Chun Chen (787255)

“…However, the abundance of HCV RNA carrying mutations on both miR-122-binding sites and whose stability was supported by ectopically expressed miR-122 mimetics with compensatory mutations also decreased in Rab27a-depleted cells. This result indicates that the effect of Rab27a depletion on HCV RNA abundance does not depend on the formation of 5’ terminal HCV/miR-122 RNA complexes, but that miR-122 has a Rab27a-dependent function in the HCV lifecycle, likely the downregulation of a cellular inhibitor of HCV gene expression. …”

Effect of telomerase siRNA transfection on AFP production by HepG2/C3A and PLC/PRF/5 cells. by Roula Tahtouh (714734)

“…After incubation, 50 μL of the supernatant was collected and tested by ELISA for AFP quantification. (A) The inhibition of telomerase by hTERT siRNA induced a decrease in AFP production by HepG2/C3A cells. …”

<i>Rpl5</i> mutant ES cells exhibit a p53-independent G2 cell cycle arrest. by Sharon A. Singh (524066)

“…In contrast, the cell cycle profile of the <i>Rpl5</i> mutant ES cells exhibited a three-fold increase in the G2 phase with a concomitant decrease in the G1 and S phases, consistent with a delayed G2 phase transition (A, C) (three independent pooled experiments). …”

Next-generation sequencing analyses of parental and mutant MeV stocks documenting the stability of the introduced mutations. by Lorellin A. Durnell-Bettis (22656332)