Mefunidone decreased collagen I, collagen III, α-smooth muscle actin (α-SMA) and fibronectin (FN) expression in the obstructive kidneys after UUO at 14 days. by Chunyan Liu (44864)

“…<p><b><i>A</i>.</b> Mefunidone affected collagen I (left) and collagen III (right) protein expression in the obstructed kidneys stained by immunohistochemistry (×200). …”

Hsp72 overexpression decreases total NF-κB-p65 in resting cells and reduces steady state IκBα protein levels. by Patrick W. Sheppard (586664)

“…<p>A. Model simulations directly reducing IκBα protein synthesis suggest mechanism inconsistent with data. …”

Effects of <em>APOA5 −1131T>C</em> (rs662799) on Fasting Plasma Lipids and Risk of Metabolic Syndrome: Evidence from a Case-Control Study in China and a Meta-Analysis by Chunxiao Xu (311834)

“…<div><p>The apolipoprotein A5 (<i>APOA5</i>) gene <i>−1131T>C</i> (rs662799) has been suggested to be involved in the pathway of lipid homeostasis and the development of metabolic syndrome (MetS). …”

IGF-I decreases cell doubling time and induces the expression of Survivin at both mRNA and protein levels in the NRP-152 rat prostatic epithelial cell line. by Kyung Song (211116)

Zbtb7a is a widespread promoter- and enhancer-associated factor. by José Miguel Ramos Pittol (5309837)

“…(G) Enrichment of GO annotations among genes whose promoters are associated with Zbtb7a peaks (first column, “Zbtb7a promoter peak”) or with increased or decreased mRNA expression in control fibroblasts, compared to Zbtb7a-knockdown fibroblasts (second and third columns). …”

The <em>ABCA1</em> Gene R230C Variant Is Associated with Decreased Risk of Premature Coronary Artery Disease: The Genetics of Atherosclerotic Disease (GEA) Study by Teresa Villarreal-Molina (119637)

“…</p> <h3>Results</h3><p>The C230 allele was significantly associated with both lower HDL-C levels and a lower risk of premature CAD as compared to controls (OR = 0.566; <em>P_add</em> = 1.499×10⁻⁵). …”

Selectivity of PRMT5 inhibition with C220. by Shelby L. Sloan (10803222)

“…For all cell lines, effects of PRMT5 inhibition with C220 treatment on biomarkers of PRMT5 activity shows a dose-dependent decrease in global marks of symmetric di-methylarginine (SDMA) and symmetric di-methylation of histone H4 arginine-3 (H4R3me2s) with a minimal effect to PRMT5 or global asymmetric di-methylarginine (ADMA). …”

Table_1_Previous Use of Anti-Vascular Endothelial Growth Factor Receptor Agents Decreases Efficacy of Fruquintinib in Metastatic Colorectal Cancer Refractory to Standard Therapies.... by Lei Wang (6656)

“…Progression-free survival (PFS) and overall survival (OS) were assessed by a Kaplan-Meier analysis and log-rank test. A Cox regression model was performed to identify independent prognostic factors.…”

Propofol increased the number of the hippocampal pyramidal neurons and decreased the expression of the LC3-II protein and the number of lysosomes and autophagosomes in the ischemic... by Derong Cui (326839)

“…Statistical analyses were performed using a one-way ANOVA. **<i>p</i> < 0.01 vs. control group; ^##<i>p</i> < 0.01 vs. …”

Loss of <i>FGR41</i> attenuates virulence in a host immune system dependent manner. by Andrew S. Wagner (11331477)

Presentation_1_Phosphodiesterase Type 5 (PDE5) Inhibitors Sensitize Topoisomerase II Inhibitors in Killing Prostate Cancer Through PDE5-Independent Impairment of HR and NHEJ DNA Re... by Jo-Fan Chang (6237680)

“…In conclusion, the data suggest that sildenafil and vardenafil induce PDE5-independent apoptotic sensitization to doxorubicin (or other topoisomerase II inhibitors) through impairment of both HR and NHEJ repair systems that are evident by a decrease of nuclear Rad51 levels and their foci formation in the nucleus, and an inhibition of Ku80 DNA end-binding capability. …”

The expression level of hub genes in EOC tissues at different stages. by Ting Gui (304563)

“…According to the result, there were significant variations in the expression levels of CDC45, CDCA5, KIF4A, and ESPL1 (a-d). The overall trends indicated that the expression of these four genes decreased gradually with the continuous progression of OC.…”

Image_1_Comparison Of The Gut Microbiota In Different Age Groups In China.tif by Hang Yan (2792143)

“…Our study divided the subjects (n=614) into two groups by using 50 years as the age cut-off point for the grouping. …”

Table_1_Comparison Of The Gut Microbiota In Different Age Groups In China.xlsx by Hang Yan (2792143)

“…Our study divided the subjects (n=614) into two groups by using 50 years as the age cut-off point for the grouping. …”

Hepcidin decreased DMT1 and FPN at mRNA and protein level but did not alter most calcium transporter and calcium binding protein expression at mRNA level. by Supathra Phoaubon (11559357)

A representative case of a 68-year-old man with local tumor progression. by Yuan-Mao Lin (6934361)

“…<p>A 68-year-old man (body weight, 70.4 kg; BMI, 24.1 kg/m²) underwent multiphasic hepatic CT with dual source DECT at half reduced contrast medium dose. …”

Decreased Pattern Recognition Receptor Signaling, Interferon-Signature, and Bactericidal/Permeability-Increasing Protein Gene Expression in Cord Blood of Term Low Birth Weight Huma... by Vikas Vikram Singh (406168)

Outcome measures recorded in the trade-off test. Willingness to move away from the two companions kept in a pen adjacent to the test area in trade-off with grain was measured.... by Sarah Kappel (4437403)

“…Willingness to move away from the two companions kept in a pen adjacent to the test area in trade-off with grain was measured. …”

A Conserved Endoplasmic Reticulum Membrane Protein Complex (EMC) Facilitates Phospholipid Transfer from the ER to Mitochondria by Sujoy Lahiri (644161)

“…We show that a strain missing multiple components of the conserved ER membrane protein complex (EMC) has decreased phosphatidylserine (PS) transfer from the ER to mitochondria. …”

Table_5_Dynamics of Viral Infection and Evolution of SARS-CoV-2 Variants in the Calabria Area of Southern Italy.XLSX by Carmela De Marco (13166325)

“…Among the genomes identified in this study, some were distributed all over Europe (B1_S477N, Alpha_L5F, Delta_T95, Delta_G181V, and Delta_A222V), some were distributed in the majority of Italian regions (B1_S477N, B1_Q675H, Delta_T95I and Delta_A222V), and some were present mainly in Calabria (B1_S477N_T29I, B1_S477N_T29I_E484Q, Alpha_A67S, Alpha_A701S, and Alpha_T724I). …”