Proteasome Inhibitors Block DNA Repair and Radiosensitize Non-Small Cell Lung Cancer by Kyle R. Cron (455028)

“…Proteasome inhibition resulted in an 80–90% decrease in homologous recombination (HR), a 50% decrease in expression of NF-κB-inducible HR genes <i>BRCA1</i> and <i>FANCD2</i>, and a reduction of BRCA1, FANCD2 and RAD51 ionizing radiation-induced foci. …”

Y-27632 treatment of P19 cells inhibits the differentiation of primitive endoderm. by Roman J. Krawetz (309735)

“…FACS analysis demonstrates a significant decrease in GATA-6 and Troma-1 positive cells with Y-27632 present (K). …”

PDIM production and export is required for induction of the macrophage type I IFN response. by Amy K. Barczak (525258)

“…<p>(A) Measurement of macrophage CCL5 production after infection with <i>Mtb</i> strains. …”

C4 overexpression led to dendritic spine alterations in apical arbors of L2/3 mPFC neurons. by Ashley L. Comer (8299128)

“…<i>N</i> = 240 dendrites from 84 mice (20 dendrites per each time point; 20 dendrites × 4 time points × 3 conditions). …”

Effects of endogenous prostanoids and selective agonists on the beating rate of neonatal rat cardiomyocytes. by Hakima Mechiche (308181)

“…“bradyarrhythmia” indicated a decrease of more than 50%; “tachyarrhythmia” indicated an increase of more than 50% with chaotic, asynchronous, activity of the myocytes <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0045273#pone.0045273-Li1" target="_blank">[13]</a>; <i>n</i> is the number of preparations on which brady- or tachy-arrhythmia was observed.…”

Trial study protocol. by Miriam Serrano Soliva (19485617)

“…Specifically, the intervention group, presented a decrease in score on the anxiety scale of -5.35 (p < 0.001) points on average and a decrease in score on the depression scale of -5.88 (p < 0.001) points on average, while in the control group the levels worsened with the progression of time.…”

Potential effect of the differential genetic expression of PBMCs. by Michael J. Baine (230373)

“…Letters represent individual cell populations: <b>a</b>, Cytotoxic T-lymphocytes (CTL); <b>b</b>, B-cells. Decrease in genes associated with points <b>a</b> and <b>b</b> may represent a decrease in their respective associated cell's population.…”

Flow diagram. by Miriam Serrano Soliva (19485617)

“…Specifically, the intervention group, presented a decrease in score on the anxiety scale of -5.35 (p < 0.001) points on average and a decrease in score on the depression scale of -5.88 (p < 0.001) points on average, while in the control group the levels worsened with the progression of time.…”

Written consent. by Miriam Serrano Soliva (19485617)

“…Specifically, the intervention group, presented a decrease in score on the anxiety scale of -5.35 (p < 0.001) points on average and a decrease in score on the depression scale of -5.88 (p < 0.001) points on average, while in the control group the levels worsened with the progression of time.…”

Ethics committee. by Miriam Serrano Soliva (19485617)

“…Specifically, the intervention group, presented a decrease in score on the anxiety scale of -5.35 (p < 0.001) points on average and a decrease in score on the depression scale of -5.88 (p < 0.001) points on average, while in the control group the levels worsened with the progression of time.…”

CONSORT checklist. by Miriam Serrano Soliva (19485617)

“…Specifically, the intervention group, presented a decrease in score on the anxiety scale of -5.35 (p < 0.001) points on average and a decrease in score on the depression scale of -5.88 (p < 0.001) points on average, while in the control group the levels worsened with the progression of time.…”

pQTL analysis of IFN-α and IFN-γ receptor levels and responses. by Christian Lundtoft (4068679)

“…Blue indicates a decrease in minor allele carriers, while red indicates an increase in minor allele carriers. …”

Table_6_Biological, Behavioral and Physiological Consequences of Drug-Induced Pregnancy Termination at First-Trimester Human Equivalent in an Animal Model.DOCX by Christina Camilleri (6751091)

“…Following drug/vehicle administration, only the pregnancy termination group (pregnant, drug) displayed a significant decrease in body weight, food intake, locomotor activity-related behaviors and home-cage activity relative to the control group (non-pregnant, vehicle). …”

Table_10_Biological, Behavioral and Physiological Consequences of Drug-Induced Pregnancy Termination at First-Trimester Human Equivalent in an Animal Model.DOCX by Christina Camilleri (6751091)

“…Following drug/vehicle administration, only the pregnancy termination group (pregnant, drug) displayed a significant decrease in body weight, food intake, locomotor activity-related behaviors and home-cage activity relative to the control group (non-pregnant, vehicle). …”

Table_12_Biological, Behavioral and Physiological Consequences of Drug-Induced Pregnancy Termination at First-Trimester Human Equivalent in an Animal Model.DOCX by Christina Camilleri (6751091)

“…Following drug/vehicle administration, only the pregnancy termination group (pregnant, drug) displayed a significant decrease in body weight, food intake, locomotor activity-related behaviors and home-cage activity relative to the control group (non-pregnant, vehicle). …”

Table_9_Biological, Behavioral and Physiological Consequences of Drug-Induced Pregnancy Termination at First-Trimester Human Equivalent in an Animal Model.DOCX by Christina Camilleri (6751091)

“…Following drug/vehicle administration, only the pregnancy termination group (pregnant, drug) displayed a significant decrease in body weight, food intake, locomotor activity-related behaviors and home-cage activity relative to the control group (non-pregnant, vehicle). …”

Table_7_Biological, Behavioral and Physiological Consequences of Drug-Induced Pregnancy Termination at First-Trimester Human Equivalent in an Animal Model.DOCX by Christina Camilleri (6751091)

“…Following drug/vehicle administration, only the pregnancy termination group (pregnant, drug) displayed a significant decrease in body weight, food intake, locomotor activity-related behaviors and home-cage activity relative to the control group (non-pregnant, vehicle). …”

Table_8_Biological, Behavioral and Physiological Consequences of Drug-Induced Pregnancy Termination at First-Trimester Human Equivalent in an Animal Model.DOCX by Christina Camilleri (6751091)

“…Following drug/vehicle administration, only the pregnancy termination group (pregnant, drug) displayed a significant decrease in body weight, food intake, locomotor activity-related behaviors and home-cage activity relative to the control group (non-pregnant, vehicle). …”

Table_15_Biological, Behavioral and Physiological Consequences of Drug-Induced Pregnancy Termination at First-Trimester Human Equivalent in an Animal Model.DOCX by Christina Camilleri (6751091)

“…Following drug/vehicle administration, only the pregnancy termination group (pregnant, drug) displayed a significant decrease in body weight, food intake, locomotor activity-related behaviors and home-cage activity relative to the control group (non-pregnant, vehicle). …”

Image_1_Biological, Behavioral and Physiological Consequences of Drug-Induced Pregnancy Termination at First-Trimester Human Equivalent in an Animal Model.TIF by Christina Camilleri (6751091)

“…Following drug/vehicle administration, only the pregnancy termination group (pregnant, drug) displayed a significant decrease in body weight, food intake, locomotor activity-related behaviors and home-cage activity relative to the control group (non-pregnant, vehicle). …”