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19841
D-TRP(8)-γMSH Prevents the Effects of Endotoxin in Rat Skeletal Muscle Cells through TNFα/NF-KB Signalling Pathway - Fig 9
Published 2016“…<p>Effect of D-Trp(8)-γMSH (0, 50 or 200 nM) on; phospho-NF-κB(p65)Ser276 (A), NF-κB(p65) (B), phospho-Akt (C) Akt (D), IGF-I mRNA (E) and MHC I mRNA (F) in L6 myotubes cell cultures incubated with TNFα (10 μg/ml) or DMEM. …”
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19842
A Prevalent Variant in <em>PPP1R3A</em> Impairs Glycogen Synthesis and Reduces Muscle Glycogen Content in Humans and Mice
Published 2008“…Human genetic disorders primarily affecting skeletal muscle glycogen turnover are well-recognised, but rare. We previously reported that a frameshift/premature stop mutation in <em>PPP1R3A</em>, the gene encoding R<sub>GL</sub>, a key regulator of muscle glycogen metabolism, was present in 1.36% of participants from a population of white individuals in the UK. …”
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19843
(A) CD45 cells express Sema4D
Published 2011“…(right) As shown, ∼85% of the leukocytes express Sema4D. Error bars indicate mean ± SD. *, P < 0.0001. Bar, 50 μm. (B) WT-derived bone marrow cells rescue tumor burden. …”
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19844
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19845
Dendritic Hydrogels Induce Immune Modulation in Human Keratinocytes and Effectively Eradicate Bacterial Pathogens
Published 2021“…Biomaterials that have inherent antibacterial properties and do not require the use of antibiotics present an attractive and feasible avenue to achieve this goal. Herein, we demonstrate the effect of a new class of cationic hydrogels based on amino-functional hyperbranched dendritic–linear–dendritic copolymers (HBDLDs) exhibiting excellent antimicrobial activity toward a wide range of clinical Gram-positive and Gram-negative bacteria, including drug-resistant strains isolated from wounds. …”
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19846
Demographic data.
Published 2025“…Deliberate practice is an instructional model designed to improve performance by engaging trainees in structured, repetitive practice with immediate feedback provided by supervisors. We developed a multifaceted simulation informed by deliberate practice and tested the hypothesis that trainee skills and reported confidence would increase after training. …”
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19847
Dynamical models of all Intrinsic currents.
Published 2024“…To examine the effects of CLAS on spindles, we propose a biophysical thalamocortical model for slow oscillations (SOs) and sleep spindles. …”
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19848
Model parameters, their values, and descriptions.
Published 2024“…To examine the effects of CLAS on spindles, we propose a biophysical thalamocortical model for slow oscillations (SOs) and sleep spindles. …”
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19849
Table_1_Visuomotor Adaptation Brain Changes During a Spaceflight Analog With Elevated Carbon Dioxide (CO2): A Pilot Study.docx
Published 2021“…Additionally, we compare brain activity between this NASA campaign (30-day HDBR+CO<sub>2</sub>) and a different campaign with a separate set of participants (60-day HDBR with normal atmospheric CO<sub>2</sub> levels, n = 8; 34.25 ± 7.9 years) to characterize the specific effects of CO<sub>2</sub>. …”
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19850
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19851
Data Sheet 1_Flourishing as a highly sensitive person: a mixed method study on the role of nature connectedness and chaotic home environment.xlsx
Published 2025“…We hypothesise that a chaotic home environment will negatively impact flourishing, particularly for those who are highly sensitive, while being connected with nature will have a more positive effect on them. …”
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19852
Metabolic Responses of a Phototrophic Co-Culture Enriched from a Freshwater Sediment on Changing Substrate Availability and its Relevance for Biogeochemical Iron Cycling
Published 2020“…Here, we exposed a phototrophic co-culture (<i>Rhodopseudomonas</i> sp. and <i>Chlorobium</i> sp.) that was isolated from a littoral freshwater sediment to a variety of substrates (acetate, Fe(II), or H<sub>2</sub>) and followed the abundance of individual microbial partners based on their characteristic light absorption pattern. …”
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19853
Supplementary file 1_Flourishing as a highly sensitive person: a mixed method study on the role of nature connectedness and chaotic home environment.docx
Published 2025“…We hypothesise that a chaotic home environment will negatively impact flourishing, particularly for those who are highly sensitive, while being connected with nature will have a more positive effect on them. …”
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19854
Microscopic Temperature Control Reveals Cooperative Regulation of Actin–Myosin Interaction by Drebrin E
Published 2021“…Here, by applying the microscopic heat pulse method to actomyosin motility assay, the regulatory mechanism is examined from the room temperature up to 37 °C without a thermal denaturing of proteins. We show that the inhibition of actomyosin motility by drebrin E is eliminated immediately and reversibly during heating and depends on drebrin E concentration. …”
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19855
Microscopic Temperature Control Reveals Cooperative Regulation of Actin–Myosin Interaction by Drebrin E
Published 2021“…Here, by applying the microscopic heat pulse method to actomyosin motility assay, the regulatory mechanism is examined from the room temperature up to 37 °C without a thermal denaturing of proteins. We show that the inhibition of actomyosin motility by drebrin E is eliminated immediately and reversibly during heating and depends on drebrin E concentration. …”
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19856
Microscopic Temperature Control Reveals Cooperative Regulation of Actin–Myosin Interaction by Drebrin E
Published 2021“…Here, by applying the microscopic heat pulse method to actomyosin motility assay, the regulatory mechanism is examined from the room temperature up to 37 °C without a thermal denaturing of proteins. We show that the inhibition of actomyosin motility by drebrin E is eliminated immediately and reversibly during heating and depends on drebrin E concentration. …”
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19857
Microscopic Temperature Control Reveals Cooperative Regulation of Actin–Myosin Interaction by Drebrin E
Published 2021“…Here, by applying the microscopic heat pulse method to actomyosin motility assay, the regulatory mechanism is examined from the room temperature up to 37 °C without a thermal denaturing of proteins. We show that the inhibition of actomyosin motility by drebrin E is eliminated immediately and reversibly during heating and depends on drebrin E concentration. …”
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19858
Microscopic Temperature Control Reveals Cooperative Regulation of Actin–Myosin Interaction by Drebrin E
Published 2021“…Here, by applying the microscopic heat pulse method to actomyosin motility assay, the regulatory mechanism is examined from the room temperature up to 37 °C without a thermal denaturing of proteins. We show that the inhibition of actomyosin motility by drebrin E is eliminated immediately and reversibly during heating and depends on drebrin E concentration. …”
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19859
Microscopic Temperature Control Reveals Cooperative Regulation of Actin–Myosin Interaction by Drebrin E
Published 2021“…Here, by applying the microscopic heat pulse method to actomyosin motility assay, the regulatory mechanism is examined from the room temperature up to 37 °C without a thermal denaturing of proteins. We show that the inhibition of actomyosin motility by drebrin E is eliminated immediately and reversibly during heating and depends on drebrin E concentration. …”
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19860
Microscopic Temperature Control Reveals Cooperative Regulation of Actin–Myosin Interaction by Drebrin E
Published 2021“…Here, by applying the microscopic heat pulse method to actomyosin motility assay, the regulatory mechanism is examined from the room temperature up to 37 °C without a thermal denaturing of proteins. We show that the inhibition of actomyosin motility by drebrin E is eliminated immediately and reversibly during heating and depends on drebrin E concentration. …”