TDP-43 is localized to mitochondria, induces mitochondrial damage and suppresses mitochondrial complex I and reduces mitochondrial ATP synthesis. by Peng Wang (34436)

“…Cells were stained using JC1 (C) or mitoSOX-red (D) respectively and analyzed using flow cytometry. (<b>E</b>) Mitochondrial ATP synthesis was decreased in cells expressing either Wt or A315T-mutant TDP-43 protein. …”

Phosphate control in reducing FGF23 levels in hemodialysis patients by Cristian Rodelo-Haad (5607911)

Image1_Storage-induced mechanical changes of porcine lenses assessed with optical coherence elastography and inverse finite element modeling.pdf by Vahoura Tahsini (18816889)

“…According to iFEA, this resulted from an increased ratio of the nuclear: cortical E-modulus (4.06 and 7.06) in −80°C and −20°C frozen lenses compared to fresh lenses (3.3). …”

Figure 7 from MUC1-C Dictates PBRM1-Mediated Chronic Induction of Interferon Signaling, DNA Damage Resistance, and Immunosuppression in Triple-Negative Breast Cancer by Nami Yamashita (15100557)

“…<p>MUC1 and PBRM1 associate with decreases in responsiveness of TNBC tumors to chemotherapy. …”

Do we treat our patients or rather periodontal microbes with adjunctive antibiotics in periodontal therapy? A 16S rDNA microbial community analysis by Daniel Hagenfeld (319909)

“…We found statistically noticeable decreased richness, and increased dissimilarity in the antibiotic, but not in the placebo group after therapy. …”

Interallelic and Intergenic Incompatibilities of the <em>Prdm9</em> (<em>Hst1</em>) Gene in Mouse Hybrid Sterility by Petr Flachs (124485)

“…The <em>Hybrid sterility 1</em> gene (<em>Hst1</em>) participates in the arrest of meiosis in F₁ males of certain strains from two <em>Mus musculus</em> subspecies, e.g., PWD from <em>M. m. musculus</em> and C57BL/6J (henceforth B6) from <em>M. m. domesticus</em>. …”

Recruitment of the cellular Osh/ORP proteins is facilitated by Fis1 into tombusvirus replication compartment. by Wenwu Lin (7542863)

“…Samples were cross-linked with formaldehyde. Bottom two panels: western blot of total His₆-Osh6p and Flag-p33 in the total yeast extracts. …”

C2CD3 is crucial for the localization of the LDR and DISCO complexes. by Eloïse Bertiaux (5309927)

“…<p><b>(A)</b> Expanded centrioles from control (siCTRL) and C2CD3-depleted (siC2CD3) cells stained for C2CD3 (green) and tubulin (magenta). …”

Upon depletion of corneal conventional dendritic cells, virus titers and the local corneal damages are significantly increased in primary herpes simplex keratitis. by Kai Hu (311882)

“…<b>I:</b> Corneal nerve density was significantly decreased in cDC depleted or cDC and MΦ double-depleted corneas as compared to sham controls or MΦ depleted corneas. …”

Rae1 negatively regulates Yki/YAP in <i>Drosophila</i> and in mammalian cells. by Maryam Jahanshahi (474646)

“…(P) Reducing <i>Rae1</i> levels by concurrent <i>Rae1</i> RNAi (<i>ptc>Yki</i>^<i>S168A</i>, <i>Rae1</i>^<i>IRV</i>) further decreases salivary gland size. Glands in 7P were separated during dissection; gland on the right was overlaid into the frame with the gland on the left to provide images of two glands. …”

Table 1_Cryoablation of primary breast cancer tumors induces a systemic abscopal effect altering TIME (Tumor Immune Microenvironment) in distant tumors.xlsx by Flávia Sardela de Miranda (20365038)

DataSheet_1_Leveraging intelligent optimization for automated, cardiac-sparing accelerated partial breast treatment planning.xlsx by Joel A. Pogue (14597114)

Maternal obesity increases insulin resistance, low-grade inflammation and osteochondrosis lesions in foals and yearlings until 18 months of age by M. Robles (4801200)

DataSheet1_v1_Rejuveinix Shows a Favorable Clinical Safety Profile in Human Subjects and Exhibits Potent Preclinical Protective Activity in the Lipopolysaccharide-Galactosamine Mou... by Fatih M. Uckun (447782)

“…</p><p>Methods: A phase 1, double-blind, placebo-controlled, randomized, two-part, ascending dose-escalation study was performed in participating 76 healthy volunteer human subjects in compliance with the ICH (E6) good clinical practice guidelines to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of RJX (Protocol No. …”

Data Sheet 1_Cryoablation of primary breast cancer tumors induces a systemic abscopal effect altering TIME (Tumor Immune Microenvironment) in distant tumors.docx by Flávia Sardela de Miranda (20365038)

Enhanced hippocampal excitation, susceptibility to induced seizures, and altered brain oscillations in <i>Ngl3</i>^−/−(Hyb) mice. by Hyejin Lee (636530)

“…<i>n</i> = 15 mice for WT and 14 for KO; *<i>P</i> < 0.05, **<i>P</i> < 0.01, Student <i>t</i> test. (E) Decreased alpha and increased theta oscillations in the temporal, but not frontal, lobes of the <i>Ngl3</i>^−/−(Hyb) brain (3 months), as shown by the power spectrum and normalized power in different frequency ranges. …”

Data Sheet 1_A peptide mimic of SOCS1 modulates equine peripheral immune cells in vitro and ocular effector functions in vivo: implications for recurrent uveitis.pdf by Lauren Stewart Stafford (17937497)

Table 1_A peptide mimic of SOCS1 modulates equine peripheral immune cells in vitro and ocular effector functions in vivo: implications for recurrent uveitis.docx by Lauren Stewart Stafford (17937497)

A simplified model to test the hypothesis that strain rate triggers cellular directional response. by Assaf Zaritsky (137666)

“…HGF/SF-treated DA3 cells migrate in an enhanced directional manner (<b>D</b>), compared to control cells (<b>C</b>), similarly to the corresponding theoretical purple and yellow plot in (<b>B</b>). (<b>E</b>) Morphology of single DA3 cells as function of time and distance from the wound. …”

Table_1_Leveraging intelligent optimization for automated, cardiac-sparing accelerated partial breast treatment planning.docx by Joel A. Pogue (14597114)