Showing 17,861 - 17,880 results of 30,088 for search '(( 50 ((ns decrease) OR (((nn decrease) OR (a decrease)))) ) OR ( 2 step decrease ))', query time: 0.88s Refine Results
  1. 17861
  2. 17862

    Data_Sheet_1_SWL-1 Reverses Fluconazole Resistance in Candida albicans by Regulating the Glycolytic Pathway.doc by Xiao-Ning Li (2008540)

    Published 2020
    “…In this study, we show that SWL-1 reverses resistance to fluconazole in C. albicans when delivered in combination, with a sharp decrease in the IC<sub>50</sub> of fluconazole from >200 to 3.74 ± 0.25 μg/ml, and also reverses the fluconazole resistance of C. albicans in vitro, with IC<sub>50</sub> from >200 to 5.3 ± 0.3 μg/ml. …”
  3. 17863

    An Integrated Disease/Pharmacokinetic/Pharmacodynamic Model Suggests Improved Interleukin-21 Regimens Validated Prospectively for Mouse Solid Cancers by Moran Elishmereni (203218)

    Published 2011
    “…Simulations of the verified model surfaced important therapeutic insights: (1) Fractionating the standard daily regimen (50 µg/dose) into a twice daily schedule (25 µg/dose) is advantageous, yielding a significantly lower tumor mass (45% decrease); (2) A low-dose (12 µg/day) regimen exerts a response similar to that obtained under the 50 µg/day treatment, suggestive of an equally efficacious dose with potentially reduced toxicity. …”
  4. 17864
  5. 17865
  6. 17866
  7. 17867
  8. 17868
  9. 17869
  10. 17870

    <b>Genome assembly at chromosome level and evolutionary analysis of </b><i><b>Coregonus ussurinsis</b></i><b> Berg</b> by Tianqing Huang (9743483)

    Published 2024
    “…The sequence length was 2,627.19 Mb with a contig N50 length of 4.27 Mb. Then 3,109 contigs were assembled into scaffolds, resulting in a genome assembly with 40 chromosomes and a scaffold N50 length of 62.20 Mb, and the size of the genome was 2.51 Gb, and the integrity was more than 95% by BUSCO test. …”
  11. 17871
  12. 17872
  13. 17873
  14. 17874
  15. 17875

    Assessment of sesquiterpene lactones isolated from <i>Mikania</i> plants species for their potential efficacy against <i>Trypanosoma cruzi</i> and <i>Leishmania</i> sp. by Laura C. Laurella (469416)

    Published 2017
    “…<div><p>Four sesquiterpene lactones, mikanolide, deoxymikanolide, dihydromikanolide and scandenolide, were isolated by a bioassay-guided fractionation of <i>Mikania variifolia</i> and <i>Mikania micrantha</i> dichloromethane extracts. …”
  16. 17876

    C-I TF screen quantitative phenotypic analyses. by Eswar Prasad R. Iyer (177455)

    Published 2013
    “…The direction of arrow represents increase (up), decrease (down) or no change (hyphen). Size bar corresponds to 50 microns.…”
  17. 17877

    Combinatorial Synthesis and in Vitro Evaluation of a Biaryl Hydroxyketone Library as Antivirulence Agents against MRSA by Guanping Yu (1345770)

    Published 2014
    “…An acylation bond-forming process afforded resorcinols (<b>1</b>) and aryloxy acetonitriles (<b>2</b>) as synthons. A Lewis-acid-activated Friedel–Crafts’ acylation step involving a nitrile functionality of <b>2</b> by ZnCl<sub>2</sub>, followed by nucleophilic attack by <b>1</b> was executed to obtain biaryl hydroxyketones in excellent yields. …”
  18. 17878

    Combinatorial Synthesis and in Vitro Evaluation of a Biaryl Hydroxyketone Library as Antivirulence Agents against MRSA by Guanping Yu (1345770)

    Published 2014
    “…An acylation bond-forming process afforded resorcinols (<b>1</b>) and aryloxy acetonitriles (<b>2</b>) as synthons. A Lewis-acid-activated Friedel–Crafts’ acylation step involving a nitrile functionality of <b>2</b> by ZnCl<sub>2</sub>, followed by nucleophilic attack by <b>1</b> was executed to obtain biaryl hydroxyketones in excellent yields. …”
  19. 17879

    Effect of mutations on neutralization by antibodies elicited by 2x BNT162b2 vaccination, Delta breakthrough after 2x mRNA vaccination, or primary Delta infection. by Allison J. Greaney (11046384)

    Published 2022
    “…<p><b>(A)</b> Neutralization titer 50% (NT50) of spike-pseudotyped lentiviral particles by sera or plasmas from individuals with various exposure histories. …”
  20. 17880

    RSK and PDK1 contribute to Ca<sup>2+</sup>-induced force, MYPT1 and RLC<sub>20</sub> phosphorylation in α-toxin permeabilized rabbit pulmonary artery SM. by Mykhaylo Artamonov (389145)

    Published 2013
    “…<p>RSK inhibitor, BI-D1870 is without effect on the actomyosin ATPase. (A) RSK inhibitor, BI-D1870 (100nM), right shifted the pCa<sup>2+</sup>-force relationship and decreased the maximal force (milli-Newtons, mN) at each intracellular Ca<sup>2+</sup> concentration (pCa) compared to the Control diluent, DMSO. …”