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step decrease » sizes decrease (Expand Search), teer decrease (Expand Search), we decrease (Expand Search)
ns decrease » _ decrease (Expand Search), we decrease (Expand Search), use decreased (Expand Search)
nn decrease » _ decrease (Expand Search), mean decrease (Expand Search), gy decreased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
2 step » _ step (Expand Search), a step (Expand Search)
step decrease » sizes decrease (Expand Search), teer decrease (Expand Search), we decrease (Expand Search)
ns decrease » _ decrease (Expand Search), we decrease (Expand Search), use decreased (Expand Search)
nn decrease » _ decrease (Expand Search), mean decrease (Expand Search), gy decreased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
2 step » _ step (Expand Search), a step (Expand Search)
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17861
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17862
Data_Sheet_1_SWL-1 Reverses Fluconazole Resistance in Candida albicans by Regulating the Glycolytic Pathway.doc
Published 2020“…In this study, we show that SWL-1 reverses resistance to fluconazole in C. albicans when delivered in combination, with a sharp decrease in the IC<sub>50</sub> of fluconazole from >200 to 3.74 ± 0.25 μg/ml, and also reverses the fluconazole resistance of C. albicans in vitro, with IC<sub>50</sub> from >200 to 5.3 ± 0.3 μg/ml. …”
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17863
An Integrated Disease/Pharmacokinetic/Pharmacodynamic Model Suggests Improved Interleukin-21 Regimens Validated Prospectively for Mouse Solid Cancers
Published 2011“…Simulations of the verified model surfaced important therapeutic insights: (1) Fractionating the standard daily regimen (50 µg/dose) into a twice daily schedule (25 µg/dose) is advantageous, yielding a significantly lower tumor mass (45% decrease); (2) A low-dose (12 µg/day) regimen exerts a response similar to that obtained under the 50 µg/day treatment, suggestive of an equally efficacious dose with potentially reduced toxicity. …”
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17864
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17865
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17866
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17867
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17868
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17869
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17870
<b>Genome assembly at chromosome level and evolutionary analysis of </b><i><b>Coregonus ussurinsis</b></i><b> Berg</b>
Published 2024“…The sequence length was 2,627.19 Mb with a contig N50 length of 4.27 Mb. Then 3,109 contigs were assembled into scaffolds, resulting in a genome assembly with 40 chromosomes and a scaffold N50 length of 62.20 Mb, and the size of the genome was 2.51 Gb, and the integrity was more than 95% by BUSCO test. …”
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17871
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17872
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17873
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17874
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17875
Assessment of sesquiterpene lactones isolated from <i>Mikania</i> plants species for their potential efficacy against <i>Trypanosoma cruzi</i> and <i>Leishmania</i> sp.
Published 2017“…<div><p>Four sesquiterpene lactones, mikanolide, deoxymikanolide, dihydromikanolide and scandenolide, were isolated by a bioassay-guided fractionation of <i>Mikania variifolia</i> and <i>Mikania micrantha</i> dichloromethane extracts. …”
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17876
C-I TF screen quantitative phenotypic analyses.
Published 2013“…The direction of arrow represents increase (up), decrease (down) or no change (hyphen). Size bar corresponds to 50 microns.…”
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17877
Combinatorial Synthesis and in Vitro Evaluation of a Biaryl Hydroxyketone Library as Antivirulence Agents against MRSA
Published 2014“…An acylation bond-forming process afforded resorcinols (<b>1</b>) and aryloxy acetonitriles (<b>2</b>) as synthons. A Lewis-acid-activated Friedel–Crafts’ acylation step involving a nitrile functionality of <b>2</b> by ZnCl<sub>2</sub>, followed by nucleophilic attack by <b>1</b> was executed to obtain biaryl hydroxyketones in excellent yields. …”
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17878
Combinatorial Synthesis and in Vitro Evaluation of a Biaryl Hydroxyketone Library as Antivirulence Agents against MRSA
Published 2014“…An acylation bond-forming process afforded resorcinols (<b>1</b>) and aryloxy acetonitriles (<b>2</b>) as synthons. A Lewis-acid-activated Friedel–Crafts’ acylation step involving a nitrile functionality of <b>2</b> by ZnCl<sub>2</sub>, followed by nucleophilic attack by <b>1</b> was executed to obtain biaryl hydroxyketones in excellent yields. …”
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17879
Effect of mutations on neutralization by antibodies elicited by 2x BNT162b2 vaccination, Delta breakthrough after 2x mRNA vaccination, or primary Delta infection.
Published 2022“…<p><b>(A)</b> Neutralization titer 50% (NT50) of spike-pseudotyped lentiviral particles by sera or plasmas from individuals with various exposure histories. …”
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17880
RSK and PDK1 contribute to Ca<sup>2+</sup>-induced force, MYPT1 and RLC<sub>20</sub> phosphorylation in α-toxin permeabilized rabbit pulmonary artery SM.
Published 2013“…<p>RSK inhibitor, BI-D1870 is without effect on the actomyosin ATPase. (A) RSK inhibitor, BI-D1870 (100nM), right shifted the pCa<sup>2+</sup>-force relationship and decreased the maximal force (milli-Newtons, mN) at each intracellular Ca<sup>2+</sup> concentration (pCa) compared to the Control diluent, DMSO. …”