Showing 81 - 100 results of 4,160 for search '(( 50 ((ns decrease) OR (((nn decrease) OR (mean decrease)))) ) OR ( 5 ht decrease ))', query time: 0.44s Refine Results
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    Structure-Based Design of a Chemical Probe Set for the 5‑HT<sub>5A</sub> Serotonin Receptor by Anat Levit Kaplan (12126567)

    Published 2022
    “…Docking over 6 million molecules against a 5-HT<sub>5A</sub>R homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT<sub>5A</sub>R with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …”
  8. 88

    Structure-Based Design of a Chemical Probe Set for the 5‑HT<sub>5A</sub> Serotonin Receptor by Anat Levit Kaplan (12126567)

    Published 2022
    “…Docking over 6 million molecules against a 5-HT<sub>5A</sub>R homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT<sub>5A</sub>R with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …”
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    Decreased clonogenic capacity of U87MG and U251MG glioma cells dependent on SHG-44 concentration. by Denis Mustafov (19137870)

    Published 2025
    “…<b>(B)</b> A significant decrease in the proliferative clonal capacity of U251MG colonies was observed with 50ΜM and 100ΜM SHG-44 treatment. …”
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    Decreased phosphorylation of EIF2α underlies the impairment of arsenite-induced SG formation in LSM12-depleted cells. by Jongbo Lee (9914603)

    Published 2020
    “…Relative levels of EIF2α phosphorylation were calculated by normalizing the ratio of phospho-EIF2α to EIF2α protein levels per condition to that in control cells with no chemical treatment. Data represent means ± SEM (<i>n</i> = 3). n.s., not significant; *<i>P</i> < 0.05, **<i>P</i> < 0.01, as determined by Student <i>t</i> test. …”
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    Analysis of tumour vasculature with the addition of more HT groups. by Deepa Sharma (278210)

    Published 2020
    “…The vasculature becomes less evident in the treated groups, with decreasing numbers of stained blood vessels. Images were taken at a 20x objective lens, and the scale bar denotes ~50μm. …”
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