Short telomeres worsen diabetes severity in Akita mice and cause β-cell loss. by Nini Guo (227926)

“…<b>B</b>. Ins2^C96Y/WTmTR^−/−iG₄ mice have decreased β-cell mass compared with Ins2^C96Y/WT mice. …”

A Novel Missense Mutation, I890T, in the Pore Region of Cardiac Sodium Channel Causes Brugada Syndrome by Anna Tarradas (105463)

“…Sodium currents were studied using standard whole cell patch-clamp protocols and immunodetection experiments were performed using an antibody against human Na_v1.5 channel. A marked decrease in current density was observed in cells expressing the I890T channel (from −52.0±6.5 pA/pF, <em>n</em> = 15 to −35.9±3.4 pA/pF, <em>n</em> = 22, at −20 mV, WT and I890T, respectively). …”

Higher Recovery and Better Energy Dissipation at Faster Strain Rates in Carbon Nanotube Bundles: An <i>in-Situ</i> Study by Siddhartha Pathak (1895554)

Higher Recovery and Better Energy Dissipation at Faster Strain Rates in Carbon Nanotube Bundles: An <i>in-Situ</i> Study by Siddhartha Pathak (1895554)

Higher Recovery and Better Energy Dissipation at Faster Strain Rates in Carbon Nanotube Bundles: An <i>in-Situ</i> Study by Siddhartha Pathak (1895554)

Lignocellulosic Residues from the Brazilian Juice Processing Industry as Novel Sustainable Sources for Bioenergy Production: Preliminary Assessment Using Physicochemical Characteri... by José L. F. Alves (10436273)

“…Proximate composition revealed moisture, volatile matter, fixed carbon and ash contents in the range of 7.8-9.3%, 67.1-74.2%, 16.2-22.0% and 1.6-5.7%, respectively. Typical values for carbon (44.8-49.9 wt.%), hydrogen (5.5-6.6 wt.%) and oxygen (40.1-44.2 wt.%), with low sulfur (< 0.1 wt.%) and nitrogen (< 2.7 wt.%) contents were found. …”

<i>Kif3a</i> controls renal branching morphogenesis in a GLI3R-dependent manner. by Lijun Chi (196000)

“…<p>(A–C’’) Cytokeratin immunofluorescence demonstrating ureteric branching at E11.5 and E12.5. The branch pattern is similar among <i>WT</i> (A,B), <i>Kif3a^−/−UB</i> (A’,B’) and <i>Kif3a^−/−UB</i>;<i>Kif3a^Δ699/+</i>(constitutive expression of <i>Gli3^Δ699/+</i> in <i>Kif3a^−/−UB</i> background, A’’, B’’) kidneys. …”

The outgrowth and branching of neurites and axons are impaired in hippocampal neurons from βPix neuronal isoform KO (βPix-NIKO) mice. by Younghee Kwon (1823413)

“…The βPix-NIKO neurons show a 19% decrease in the longest neurite length, a 21% decrease in total neurite length, and a 31% decrease in average axon length compared with the WT neurons. …”

Subcutaneous transplantation of L23 cells in the ear induce fast rejection and reduced proliferative response of draining lymph node cells. A: by Lilli Kraus (302769)

“…<p>Living imaging of Luciferase-transgenic porcine B cell line L23 on day 0, 1 and 5 after placing 4×10⁵ cells subcutaneous in the ear of Lewis wt rats. …”

Bioinformatics filtering algorithm. by Nzali Campbell (477829)

GDF11 inhibits Cyclin D2 expression. by Gareth Williams (5148)

“…Cyclin D2 transcript levels are expressed relative to the levels of the house-keeping gene GAPDH (mean ± SEM; **<i>p</i><0.01, n = 6). (<b>B</b>) Densitometric analysis of western blots of lysates from Cor-1 cells treated with 25 or 50 ng/ml of GDF11 for 24 hr shows a significant decrease in Cyclin D2 protein levels (mean ± SEM; **<i>p</i><0.01, n = 3). …”

File S1 - Deficiency of the Transcriptional Repressor B Cell Lymphoma 6 (Bcl6) Is Accompanied by Dysregulated Lipid Metabolism by Christopher R. LaPensee (571785)

“…B – Weights of male Bcl6 KO mice were significantly lower than WT littermates at 3, 4, and 5 weeks of age. Each point represents mean+SE for 4 WT (solid line) and 3 KO (dotted line) male mice. …”

The potentiality of the use of tire rubber residue in mortar: analysis of physical and mechanical properties by Mônica Navarini Kurz (5887277)

“…In order to verify the best substitution ratio, the tests were carried out on reference mortar and mortar with residues in the proportions of 2,5% wt, 5% wt, 10% wt and 15% wt of substitution of sand by rubber, the reference trace is 1: 3 (cement: aggregate). …”

Regulation of endogenous mitotic recombination. by James D. Cauwood (481139)

“…^a Each value is normalized to the corresponding WT value from YPD 30°C shown in blue box. Numbers in red and blue denote statistically significant increase or decrease, respectively. …”

Ability of <i>Itga2</i>^<i>-/-</i><i>/Gp6</i>^<i>-/-</i> mice for integrin activation and degranulation. by Daniela Semeniak (7181138)

“…(B) Platelet α-degranulation was measured by P-selectin exposure and <i>Gp6</i>^-/- and dko mice displayed decreased MFI values upon GPVI stimulation compared to wt. …”

3D RBC reconstructions and dendritic comparisons. by Mellisa R. Clemons (17319503)

“…<b>F)</b> A decrease the percent of dendritic tips per RBC that terminate at the rod spherules in <i>Dscaml1</i> mutant retinas was observed compared to wildtype and <i>Bax</i> null retinas (WT:<i>Bax</i>, p = 0.350; WT:<i>Dscaml1</i>, p = 0.010; <i>Bax</i>:<i>Dscaml1</i>, p < 0.001). …”

Constitutive promoter activity in long term culture of undifferentiated hESCs. by Karin Norrman (242990)

“…Decrease of ACTB-, CMV-, PGK- and UbC-eGFP intensity from day 0 to day 50 is not significant. …”

Loop in the IB domain drives ParM monomer opening. by Natalie Ng (6560246)

“…Two simulations (ParM-ATP-2,3) consistently exhibited opening angles of ~102° after 50 ns and maintained that value, whereas in the other simulation (ParM-ATP-1), the opening angle increased beyond 105° after 100 ns and then eventually decreased to ~103° in the last 20 ns of the 200-ns simulation (<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1006683#pcbi.1006683.s004" target="_blank">S4A Fig</a>). …”

Nbs1, Xrcc4, and Brca1 play distinct roles during individual repair events. by Nicole Bennardo (93380)

“…(F) Brca1-deficient cells show a decrease in S+DEJ. As in E, amplification products are shown from sorted GFP+ cells derived from I-SceI transfection of EJ5-GFP for WT and <i>Brca1−/−</i> cell lines.…”

Expression of CD74, CNTF and bFGF after treatment with EPO or EPO-peptide. by Stephanie Busch (417837)

“…It significantly decreased in heterozygous rats by 58% (p<0.01). Homozygous animals revealed 50% (p<0.01) lower expression of bFGF than heterozygous, but still achieved a reduction in gene expression by EPO-peptide of 29% (n.s.).…”