يعرض 101 - 120 نتائج من 25,201 نتيجة بحث عن '(( 50 ((ns decrease) OR (((we decrease) OR (a decrease)))) ) OR ( 5 non decrease ))', وقت الاستعلام: 0.61s تنقيح النتائج
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    Discovery of New Inhibitors of Hepatitis C Virus NS3/4A Protease and Its D168A Mutant حسب Ittipat Meewan (7455041)

    منشور في 2019
    "…Several drugs targeting the protease have been developed, but drug-resistant mutant strains emerged. Here, we screened a library and synthesized a novel class of small molecules based on a tryptophan derivative scaffold identified as HCV NS3/4A protease inhibitors that are active against both wild type and mutant form of the protease. …"
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