Showing 221 - 240 results of 32,342 for search '(( 50 ((ns decrease) OR (((we decrease) OR (a decrease)))) ) OR ( e point decrease ))', query time: 0.91s Refine Results
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    Caspase-9 silencing decreases the expression of neuronal markers in differentiating NT2 cells. by Giuseppa Pistritto (299715)

    Published 2013
    “…For each neuronal marker, the expression in control undifferentiated NT2 cells (day 0) was set at a value of 1. Each point represents the mean ± SD of three experiments. …”
  3. 223

    Insulin ICV injection (14 mU) decreases olfactory detection in fasted rats. by Pascaline Aimé (293920)

    Published 2013
    “…The mean olfactory detection indexes were not statistically different (paired t-test, p<sup>1</sup>>0.05, ns; n = 11). (<i>C</i>) Insulin ICV injection (14 mU) decreases olfactory detection. …”
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    Exposure to low CO<sub>2</sub> levels decreases ER cholesterol levels. by Nityanand Bolshette (17396845)

    Published 2023
    “…<b>(C)</b> Total cholesterol quantification (with fluorometric assay kit) in NIH3T3 cells depleted with sterols for 2 h or exposed to different CO<sub>2</sub> levels for 4 h (mean ± SE, <i>n</i> = 3 biological replicates per condition, **<i>P</i> < 0.01, nonsignificant (ns), two-sided Student’s <i>t</i> test). <b>(D, E)</b> The free cholesterol and cholesterol ester levels in the ER membrane from the cells as in <b>(C)</b>, were quantified with shotgun lipidomics analysis (see <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002367#pbio.3002367.s007" target="_blank">S7 Fig</a> and <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002367#pbio.3002367.s012" target="_blank">S5 Table</a>) (mean ± SE, <i>n</i> = 3 independent experiments, **<i>P</i> < 0.01, *<i>P</i> < 0.05, nonsignificant (ns) two-sided Student’s <i>t</i> test). …”
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    VCP inhibition induces accumulation of ubiquitinated-proteins and decreases NFκB-expression. by Kyla Walworth (3150936)

    Published 2016
    “…The increase in ubiquitinated-protein accumulation in soluble protein-fraction suggests that the DDN<sup>DBeQ</sup> treatment alters VCP-function resulting in proteostasis-inhibition and ER-accumulation of these proteins. We also see a significant decrease in expression of tumor-mediator, NFκB in DDN/DDN<sup>DBeQ</sup> treated samples as compared to the control-vehicle, although DDN<sup>DBeQ</sup> was most effective as anticipated. …”
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    Image_1_Electroencephalographic Evidence for Individual Neural Inertia in Mice That Decreases With Time.JPEG by Andrzej Z. Wasilczuk (11945885)

    Published 2022
    “…EEG was measured after induction of and emergence from isoflurane administered near the EC<sub>50</sub> dose for loss of righting in genetically inbred mice on a timescale that minimizes pharmacokinetic confounds. …”
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    Desmosomal Cadherins Are Decreased in Explanted Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy Patient Hearts by Alexia Vite (462320)

    Published 2013
    “…Genetic studies have demonstrated the central role of desmosomal proteins in this disease, where 50% of patients harbor a mutation in a desmosmal gene. …”
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    Discovery of New Inhibitors of Hepatitis C Virus NS3/4A Protease and Its D168A Mutant by Ittipat Meewan (7455041)

    Published 2019
    “…Several drugs targeting the protease have been developed, but drug-resistant mutant strains emerged. Here, we screened a library and synthesized a novel class of small molecules based on a tryptophan derivative scaffold identified as HCV NS3/4A protease inhibitors that are active against both wild type and mutant form of the protease. …”