A computational model to predict the structural and functional consequences of missense mutations in O6-methylguanine DNA methyltransferase by Thirumal Kumar, D

“…Considering true positives, true negatives, false positives, and false negatives, three mutations (Y114E, R128G, and C145A) showed "loss of DNA repair activity," and were analyzed further using molecular dynamics simulations (MDS) using GROMACS for 50ns. MDS run showed that the C145A mutant demonstrated higher structural deviation, decreased compactness, and the binding patterns. …”
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Screening the growth inhibition mechanism of sulfate reducing bacteria by chitosan/lignosulfonate nanocomposite (CS@LS) in seawater media by Kashif, Rasool

“…As the nanocomposite concentration was increased from 50 to 500 µg/mL, the specific sulfate reduction rate (SSRR) decreased from 0.278 to 0.036 g-sulfate/g-VSS*day showing a relative sulfate reduction inhibition of 86.64% as compared to that of control. …”
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High-Rate Anaerobic Digestion of Waste Activated Sludge by Integration of Electro-Fenton Process by Feki, Emna

“…In comparison to raw sludge, EF-pretreated sludge produced the highest biogas yield (0.81 L biogas/g VS) with a high COD removal rate, reaching 96.6% at an organic loading rate (OLR) of 2.5 g VS/L. d. …”
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Global, regional, and national age-sex-specific burden of diarrhoeal diseases, their risk factors, and aetiologies, 1990–2021, for 204 countries and territories: a systematic analy... by Hmwe Hmwe, Kyu

“…FindingsIn 2021, diarrhoeal diseases caused an estimated 1·17 million (95% uncertainty interval 0·793–1·62) deaths globally, representing a 60·3% (50·6–69·0) decrease since 1990 (2·93 million [2·31–3·73] deaths). …”
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A Study Of Atmospheric Transparency Over Qena In Upper Egypt by El Shazly, S. M. [سيد محمد الشاذلي]

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Heat-stress-induced changes in enzymatic antioxidant activities and biochemical processes in bell pepper (Capsicum annuum L.) seedlings by Bello, Adewale Suraj

“…At 40 and 32 °C, HS led to a decrease in chlorophyll a (4.327 mg g–1 FW), b (1.710 mg g–1 FW), total chlorophyll (5.202 mg g–1 FW), and total carotene (1.092 mg g–1 FW) compared to the control at 25 °C (chlorophyll a 5.383 mg g–1 FW, chlorophyll b 2.358 mg g–1 FW, total chlorophyll 6.692 mg g–1 FW, and total carotene 1.817 mg g–1 FW). …”
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A computational approach for investigating the mutational landscape of RAC-alpha serine/threonine-protein kinase (AKT1) and screening inhibitors against the oncogenic E17K mutation... by Thirumal Kumar, D

“…Our predictions revealed that E17K, R67W, V164G, E319G, R391G, D32Y, L52H, L52R, and W80R were the most pathogenic mutations. …”
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Preemptive Dose Adjustment Effect on the Quality of Anticoagulation Management in Warfarin Patients With Drug Interactions: A Retrospective Cohort Study by Fahmi, Amr Mohamed

“…Over a 4-year period, 340 patients were evaluated, and 58 warfarin drug interaction encounters were identified. Mean age of the patients was (57.7 n 13.7), and 50% of them were females. …”
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Global patterns and predictions of seafloor biomass using random forests by Wei, C.-L.

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Effects of polyphenol-rich traditional herbal teas on obesity and oxidative stress in rats fed a high-fat–sugar diet by Iftikhar, Neelam

“…Total phenolic contents (TPC) of Hibiscus rosa-sinensis and Zingiber officinalis extracts were found to be 5.82 and 1.45 mg/g of dry plant material, measured as GAE, while total flavonoid contents (TFC) were 9.17 and 1.95 mg/g of dry plant material, measured as CE, respectively. …”
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ELECTRODE SUSPENSION FOR AQUEOUS SODIUM FLOW BATTERY by MESLAM, MENTALLAH MOHAMED HASSANIN MOHAMED HASSANIN

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Effect of Seagrass Liquid Extracts on Bell Pepper (Capsicum annuum) Under Salt stress Conditions. by Al-qahtani, Noora Saad

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Optimal Proactive Resource Allocation at the Extreme Edge by El Khatib, Rawan F.

“…Extensive simulation results show that OPRA outperforms a reactive baseline by yielding a 50% decrease in the subtask dropping rate and 97% decrease in the service capacity.…”
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Asymmetric effects of oil price shocks on the demand for money in Algeria by Amirouche, Chelghoum

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Environment Degradation and Economic Growth in the Qatar Economy: Evidence from a Markov Switching Equilibrium Correction Model by Charfeddine, Lanouar

“…From the economic perspective, this means that initially economic growth increases environment degradation and then declines it after a threshold point of income per capita. …”
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Determining the role of missense mutations in the POU domain of HNF1A that reduce the DNA-binding affinity: A computational approach by P., Sneha

“…Triplicate runs of molecular dynamic (MD) simulations (50ns) revealed smaller changes in patterns of deviation, fluctuation, and compactness, in complexes containing the R131Q and R131W mutations, compared to complexes containing the R203C mutant complex. …”
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The potential role of vitamin D supplementation as a gut microbiota modifier in healthy individuals by Singh, Parul

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Interface modification of compatibilized polyethylene terephthalate/polypropylene blends: Effect of compatibilization on thermomechanical properties and thermal stability by Inuwa, Ibrahim M.

“…PET, PP, and SEBS-g-MAH were melt-blended in a single stLGusing the counter rotating twin screw extruder with compatibilizer concentrations of 0, 5, 10, and 15 phr, respectively. …”
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Novel fluorinated surfactants for enhanced oil recovery in carbonate reservoirs by Al-Amodi, Adel O.

“…An adsorption isotherm showed that the maximum adsorption of surfactant‐A was 1 mg per g of rock. Core flooding experiments showed 42 % additional oil recovery using 2.5 g/L (2500 ppm) HPAM and 0.001 g/g (0.1 mass%) amphoteric surfactant at 90 °C.…”
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Mitigating Cardiotoxicity of Dendrimers: Angiotensin-(1-7) via Its Mas Receptor Ameliorates PAMAM-Induced Cardiac Dysfunction in the Isolated Mammalian Heart by Akhtar, Saghir

“…Herein, we investigated (a) the effect of polyamidoamine (PAMAM) dendrimer generation (G7, G6, G5, G4 and G3) and surface chemistry (-NH2, -COOH and -OH) on cardiac function in mammalian hearts following ischemia-reperfusion (I/R) injury, and (b) determined if any PAMAM-induced cardiotoxicity could be mitigated by Angiotensin-(1-7) (Ang-(1-7), a cardioprotective agent. …”
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