Single-Cell Electroporation Can Be Carried Out at High Efficiency by Front-Loading Micropipettes. by Joseph D. Steinmeyer (170118)

“…<p>(a) In a micropipette filled with saline (scale bar 1 mm), a front-loaded reagent diffuses over time, decreasing concentration of the sample at the tip (drawings are not to scale). …”

Identification of Vascular and Hematopoietic Genes Downstream of <em>etsrp</em> by Deep Sequencing in Zebrafish by Gustavo Gomez (114453)

“…<div><p>The transcription factor <em>etsrp</em>/<em>Er71</em>/<em>Etv2</em> is a master control gene for vasculogenesis in all species studied to date. …”

48-week chase analysis of BrdU-labeled cells and Ki67-positive cells. by Shinji Kobayashi (200371)

“…<p>BrdU-labeled cells gradually decreased in auricular cartilage (White arrowheads). …”

Effect of the labeling on cell viability, proliferation, and differentiation capacity. by Philipp Boehm-Sturm (190121)

“…<p>Photomicrographs of <i>in vitro</i> samples stained for Ki67 (A, B, I and J), nestin (C, F E and H), GFAP (D, E G, H, K and N), and βIII-tubulin (L, M, O and P). …”

The <i>Scact1</i> strain is sensitive to the F-actin stabilizing agent, jasplakinolide. by Lawrence L. LeClaire (90449)

“…Effects on WT and <i>Scact1</i> growth at 50 μg/ml jasplakinolide are shown. Jasplakinolide treatment was associated with decreased growth, increased branching and swollen hyphal tips (white arrowhead, enlarged panel to right).…”

<i>In silico</i> modeling of proCART. by Elías H. Blanco (391481)

“…Alanine substitution decreases the amphipathicity. (D) Alignment of proCART from several species. proCART alpha-helix structures predicted by <a href="mailto:NPS@" target="_blank">NPS@</a> server (amino acids 24–37 for human, and 36–50 for rodent isoform are underlined. …”

Effects of low-dose rate γ-irradiation combined with simulated microgravity on markers of oxidative stress, DNA methylation potential, and remodeling in the mouse heart by John W. Seawright (4225723)

Reinforced Two-Choice Assay and Go/No Go Assay using PROBES. by Qiang Qiu (412276)

“…Chance level of discrimination is 50%, indicated by a dashed line. <b>C</b>) Training curve in a Go/No Go training using AA as reward odor (CS+, 1∶100, v/v) and MO (CS−). …”

Network firing activity during spontaneous and stimulated conditions. by Gustavo Deco (50143)

“…<p>The network cohesion and inhibition levels are and , respectively. (<b>A</b>) Firing activity for network neurons (10 neurons in each population, as indicated on the right): raster plot (black) together with the mean rate (red curves) for each population, obtained as the convolution of the spike trains with a unit Gaussian function with 50 ms width. …”

Genome-Wide Association Study for Incident Myocardial Infarction and Coronary Heart Disease in Prospective Cohort Studies: The CHARGE Consortium by Abbas Dehghan (174878)

“…We took 60 SNPs representing these 15 loci to Stage II of discovery. …”

Video2_Human engineered cardiac tissue model of hypertrophic cardiomyopathy recapitulates key hallmarks of the disease and the effect of chronic mavacamten treatment.MP4 by Kai Wang (21246)

“…We found that chronic mavacamten treatment of R403Q ECTs: (i) shortened relaxation time, (ii) reduced APD₉₀ prolongation, (iii) upregulated ADRB2, ATP2A2, RYR2, and CACNA1C, (iv) decreased B-type natriuretic peptide (BNP) mRNA and protein expression levels, and (v) increased sarcomere length and reduced sarcomere disarray.…”

Video2_Human engineered cardiac tissue model of hypertrophic cardiomyopathy recapitulates key hallmarks of the disease and the effect of chronic mavacamten treatment.MP4 by Kai Wang (21246)

“…We found that chronic mavacamten treatment of R403Q ECTs: (i) shortened relaxation time, (ii) reduced APD₉₀ prolongation, (iii) upregulated ADRB2, ATP2A2, RYR2, and CACNA1C, (iv) decreased B-type natriuretic peptide (BNP) mRNA and protein expression levels, and (v) increased sarcomere length and reduced sarcomere disarray.…”

DataSheet_1_Adapting Rapid Diagnostic Tests to Detect Historical Dengue Virus Infections.pdf by Fernando Echegaray (11176926)

“…Sensitivity increased (53% non-endemic, 98% endemic) when tests were allowed to run beyond manufacturer recommendations (0.5 up to 3 hours), but specificity decreased in endemic samples (36%). …”

Presentation1_Comprehensive evaluation of time-varied outcomes for invasive and conservative strategies in patients with NSTE-ACS: a meta-analysis of randomized controlled trials.p... by Yi-Jing Zhao (16954137)

“…Trial data for studies with a minimum follow-up time of 30 days were included. We categorized the follow-up time into six varied periods, namely, ≤6 months, 1 year, 2 years, 3 years, 5 years, and ≥10 years. …”

Data_Sheet_1_Epidemiological characteristics and transmission dynamics of the COVID-19 outbreak in Hohhot, China: a time-varying SQEIAHR model analysis.xlsx by Yifei Ma (206062)

“…</p>Methods<p>In this study, we first investigated the epidemiological characteristics of COVID-19 cases in Hohhot, including the spatiotemporal distribution and sociodemographic distribution. …”

Image2_Human engineered cardiac tissue model of hypertrophic cardiomyopathy recapitulates key hallmarks of the disease and the effect of chronic mavacamten treatment.TIF by Kai Wang (21246)

“…We found that chronic mavacamten treatment of R403Q ECTs: (i) shortened relaxation time, (ii) reduced APD₉₀ prolongation, (iii) upregulated ADRB2, ATP2A2, RYR2, and CACNA1C, (iv) decreased B-type natriuretic peptide (BNP) mRNA and protein expression levels, and (v) increased sarcomere length and reduced sarcomere disarray.…”

Planning ahead: Dynamic models forecast blue whale distribution with applications for spatial management (data and code) by Dawn Barlow (8294067)

“…</div><div>5.Synthesis and applications: We develop and test ecological forecast models that predict sea surface temperature, net primary productivity, and blue whale suitable habitat up to three weeks in the future within New Zealand’s South Taranaki Bight region. …”

Endothelial cell activation is attenuated by everolimus via transcriptional and post-transcriptional regulatory mechanisms after drug-eluting coronary stenting by Zsolt Fejes (844136)

“…We studied the effect of everolimus on E-selectin (SELE) and VCAM1 mRNA levels when human coronary artery (HCAECs) and human umbilical vein ECs were challenged with recombinant TNF-α (100 ng/mL) for 1–24 hours in the presence or absence of everolimus using 0.5 μM concentration locally maintained by DES. …”

Video1_Human engineered cardiac tissue model of hypertrophic cardiomyopathy recapitulates key hallmarks of the disease and the effect of chronic mavacamten treatment.MP4 by Kai Wang (21246)

“…We found that chronic mavacamten treatment of R403Q ECTs: (i) shortened relaxation time, (ii) reduced APD₉₀ prolongation, (iii) upregulated ADRB2, ATP2A2, RYR2, and CACNA1C, (iv) decreased B-type natriuretic peptide (BNP) mRNA and protein expression levels, and (v) increased sarcomere length and reduced sarcomere disarray.…”

Image4_Human engineered cardiac tissue model of hypertrophic cardiomyopathy recapitulates key hallmarks of the disease and the effect of chronic mavacamten treatment.TIF by Kai Wang (21246)

“…We found that chronic mavacamten treatment of R403Q ECTs: (i) shortened relaxation time, (ii) reduced APD₉₀ prolongation, (iii) upregulated ADRB2, ATP2A2, RYR2, and CACNA1C, (iv) decreased B-type natriuretic peptide (BNP) mRNA and protein expression levels, and (v) increased sarcomere length and reduced sarcomere disarray.…”