Six Year Refractive Change among White Children and Young Adults: Evidence for Significant Increase in Myopia among White UK Children by Sara J. McCullough (846708)

“…The proportion of myopes in the UK has more than doubled over the last 50 years in children aged between 10–16 years and children are becoming myopic at a younger age. …”

Illustrative cases of fractionated radiosurgery for large brain metastases. by Joo Whan Kim (3135003)

“…<p>A 50-year-old woman was diagnosed with brain metastases 4 years after treatment for breast cancer. …”

Novel Loci for Adiponectin Levels and Their Influence on Type 2 Diabetes and Metabolic Traits: A Multi-Ethnic Meta-Analysis of 45,891 Individuals by Zari Dastani (144367)

“…We identified 8 novel loci associated with adiponectin levels and confirmed 2 previously reported loci (<em>P</em> = 4.5×10⁻⁸–1.2×10⁻⁴³). …”

datasheet1_Ozanimod for Treatment of Relapsing-Remitting Multiple Sclerosis in Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.docx by Yue Sun (197395)

“…As for the subgroup analysis, compared with 0.5 mg ozanimod, 1 mg ozanimod is related with a significant reduction of the annualized relapse rate during the treatment period (1 mg ozanimod, 0.18; 0.5 mg ozanimod, 0.24; RR, 0.05 [95% CI, 0.01, 0.09])and a decreased number of new or enlarging T2 lesions over the treatment period (1 mg ozanimod,1.58; 0.5 mg ozanimod, 2.05; RR, 0.49 [95% CI, 0.19, 0.79]). …”

datasheet1_Ozanimod for Treatment of Relapsing-Remitting Multiple Sclerosis in Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.docx by Yue Sun (197395)

“…As for the subgroup analysis, compared with 0.5 mg ozanimod, 1 mg ozanimod is related with a significant reduction of the annualized relapse rate during the treatment period (1 mg ozanimod, 0.18; 0.5 mg ozanimod, 0.24; RR, 0.05 [95% CI, 0.01, 0.09])and a decreased number of new or enlarging T2 lesions over the treatment period (1 mg ozanimod,1.58; 0.5 mg ozanimod, 2.05; RR, 0.49 [95% CI, 0.19, 0.79]). …”

Linagliptin does not increase catalase and MnSOD mRNA but trends to increase catalase protein level while significantly enhancing MnSOD protein level in G6PD^- mouse kidn... by Netanya Y. Spencer (5488931)

Data_Sheet_1_Efficacy and Safety of Probiotics for the Treatment of Alzheimer's Disease, Mild Cognitive Impairment, and Parkinson's Disease: A Systematic Review and Meta-Analysis.P... by Shuai Xiang (326486)

“…After screening 1,923 titles and abstracts about PD, we selected 5 eligible studies (n = 342 patients). …”

<i>fat-6</i> mRNA levels are induced through NHR-80 in <i>glp-1(e2141ts)</i> animals. by Jérôme Goudeau (228021)

“…Relative to <i>glp-1(e2141ts)</i> mutants, <i>K04A8.5</i> is decreased 6.4-fold in <i>daf-16(mu86);glp-1(e2141ts)</i> mutants (<i>p</i><0.01) and 1.4-fold in <i>glp-1(e2141ts);nhr-80(tm1011)</i> double mutants (Wilcoxon rank-sum test <i>p</i> value is non-significant). …”

Hemodynamic Forces Regulate Developmental Patterning of Atrial Conduction by Michael C. Bressan (674014)

“…Interestingly, mechanical loading of the embryonic atrial muscle resulted in an induction of <i>Cx40</i>, <i>Nav1.5</i> and the cell cycle marker <i>Cyclin D1,</i> while decreasing atrial pressure via <i>in vivo</i> ligation of the vitelline blood vessels results in decreased atrial conduction velocity. …”

Data from: Responses of subsoil organic carbon to climate warming and cooling is determined by microbial community rather than its molecular composition by Yuzhang Li (20150214)

“…However, warming elevated fungal-to-bacterial biomass ratio (F/B) and gram-positive to gram-negative bacterial biomass ratio (G+/G-) by 15.0% and 8.6%, respectively, whereas cooling reduced them by 4.5% and 9.6%. Warming reduced SOC storage by directly increasing F/B and G+/G- and indirectly decreasing the soil carbon-to-nitrogen ratio, whereas cooling enhanced SOC storage primarily by decreasing F/B. …”

Image_1_Aggregatibacter actinomycetemcomitans cytolethal distending toxin modulates host phagocytic function.tiff by Taewan J. Kim (16910679)

“…Phosphoinositides, also play a critical role in phagosome trafficking, serving as binding domains for effector proteins during phagosome maturation and subsequent fusion with lysosomes. We now demonstrate that AaCdt manipulates the phosphoinositide (PI) pools of phagosome membranes and alters Rab5 association. …”

Image_1_Aggregatibacter actinomycetemcomitans cytolethal distending toxin modulates host phagocytic function.tiff by Taewan J. Kim (16910679)

“…Phosphoinositides, also play a critical role in phagosome trafficking, serving as binding domains for effector proteins during phagosome maturation and subsequent fusion with lysosomes. We now demonstrate that AaCdt manipulates the phosphoinositide (PI) pools of phagosome membranes and alters Rab5 association. …”

A Facile Method to Manufacture the Sesamum Indicum Fibers by Glycolic Acid Assisted with Microwave by Boya Li (3147633)

“…The residual gum content was decreased from 34.4% to 4.2%, resulting in a cleaner micro-surface of the <i>Sesamum indicum</i> fibers with increased cellulose crystallinity (75.2%–82.5%) and thermal stability (357°C–365°C). …”

Image_2_Aggregatibacter actinomycetemcomitans cytolethal distending toxin modulates host phagocytic function.tiff by Taewan J. Kim (16910679)

“…Phosphoinositides, also play a critical role in phagosome trafficking, serving as binding domains for effector proteins during phagosome maturation and subsequent fusion with lysosomes. We now demonstrate that AaCdt manipulates the phosphoinositide (PI) pools of phagosome membranes and alters Rab5 association. …”

Image_2_Aggregatibacter actinomycetemcomitans cytolethal distending toxin modulates host phagocytic function.tiff by Taewan J. Kim (16910679)

“…Phosphoinositides, also play a critical role in phagosome trafficking, serving as binding domains for effector proteins during phagosome maturation and subsequent fusion with lysosomes. We now demonstrate that AaCdt manipulates the phosphoinositide (PI) pools of phagosome membranes and alters Rab5 association. …”

Tumor-suppression by AQHAR treatment in nude mice tumor xenograft assays. by Kejuan Li (2580184)

Lithium treatment effect on blood plasma metabolome. Metabolic network of wild-type and <i>Sca1^154Q/+</i> plasma phenotypes. by Bertrand Perroud (280954)

Decision boundary dynamics modulated by theta activity. by Nadja R. Ging-Jehli (10925910)

“…view_only=5c442294fcfb4991bb42cd902c60249c" target="_blank">https://osf.io/k38pj/?…”

Mouse models for hereditary spastic paraplegia uncover a role of PI4K2A in autophagic lysosome reformation by Mukhran Khundadze (499790)

“…The respective proteins play a role for macroautophagy/autophagy and autophagic lysosome reformation (ALR). Here, we report that <i>spg11</i> and <i>zfyve26</i> KO mice developed motor impairments within the same course of time. …”

Metformin enhances epithelial cell growth inhibition via the protein kinase–insulin-like growth factor binding protein-1 pathway by Xuping Shao (18136294)

“…In an EcSC IGFBP1 overexpression model, the ability of EcSCs to inhibit epithelial cell proliferation was enhanced (EdU positivity decreased from 38% to 25%, <i>p</i> = .0001). Furthermore, adenosine 5’-monophosphate-activated protein kinase (AMPK) phosphorylation was downregulated in EcSCs and EuSCs compared to that in NSCs (0.99 vs. 0.42, <i>p</i> = .0006/0.99 vs. 0.57, <i>p</i> = 0.0032). …”