Human Subtilisin Kexin Isozyme-1 (SKI-1)/Site-1 Protease (S1P) regulates cytoplasmic lipid droplet abundance: A potential target for indirect-acting anti-dengue virus agents by Anastasia Hyrina (3860455)

“…Pre-treatment of Huh-7.5.1 cells with PF-429242 results in a dose-dependent inhibition of DENV infection [median inhibitory dose (EC₅₀) = 1.2 microM; median cytotoxic dose (CC₅₀) = 81 microM; selectivity index (SI) = 68)] and a ~3-log decrease in DENV-2 titer with 20 microM of PF-429242. …”

An outline of our methodology. by Krishna Bathina (12883820)

Immunocytochemistry showing localization of P53, P21, NF-κB p50, NF-κB p65 and MMP-9 in presence and absence of CY2 in HCT116 cells. by Sumit Kumar Dey (385318)

“…<p>DAPI was used for genomic DNA counterstaining (A) Translocation status of P53 and P21 in control cells (upper panel) and 20 µM CY2 treated cells (lower panel). …”

PRISMA flow diagram of studies identified. by Rebecca Balasa (17583302)

“…<div><p>Objective</p><p>This systematic review examined the effectiveness of Emergency Department-based and initiated youth suicide prevention interventions for suicide attempts, suicidal ideation, hospitalization, family system functioning, and other mental health symptoms.</p><p>Methods</p><p>We searched five databases for randomized controlled trial (RCT) studies that examined Emergency Department-based and initiated suicide prevention interventions among youth aged 10 to 18 years old between May 2020 to June 2022. …”

Correlations between the percentage of total sperm motility and GABA A-α1 receptor expression in sperm. by Paweena Kaewman (14329011)

The contribution of CNVs, SNVs and Indels in patient’s receiving a diagnosis. by Kimberly Gall (11372216)

Propofol enables sustained alpha firing in thalamus. by Austin E. Soplata (4676017)

EGC inhibits breast cancer growth and LDH-A expression <i>in vivo</i>. by Zhiyu Wang (282312)

“…The results showed that in both breast cancer xenografts, the expression levels of LDH-A, Ki67 and HIF-1α were decreased in comparison to that in control groups, while apoptosis ratio was elevated in EGC-treated tumor samples detected by TUNEL method; (C) Western blotting analysis showed that the expression of HIF-1α and LDH-A in EGC-treated tumor samples were significantly decreased in comparison with control groups (left panel). …”

Link prediction in 25%, 50% and 75% of the links in networks constructed from all the words in tweets of the emo-net^<i>a</i>, emo-net^<i>b</i>, emo-net<sup><i>... by Sanda Martinčić-Ipšić (4256092)

Comparison of staining efficacy of samples acquired using BD LSRFortessa flow cytometer. by Karine Sonzogni-Desautels (6490919)

“…Increasing levels of parasite burdens (counts in Y axis) show decreasing antibody staining efficacy: > 90% (C); < 90% but > 50% (D); < 50% but > 25% (E); < 25% (F).…”

Improving osteoarthritis care by digital means - Effects of a digital self-management program after 24- or 48-weeks of treatment by Leif E. Dahlberg (7405928)

“…For the 24-week sub-sample, pain NRS decreased monthly by -0.43 units (95% CI -0.51, -0.35, mean knee pain from 5.6 to 3.1, and hip pain from 5.9 to 3.8) and 30CST repetitions increased monthly by 0.76 repetitions (95% CI 0.64, 0.89 mean for knee from 10.0 to 14.3, and for hip from 10.9 to 14.8). …”

Additional Analysis of visually induced calcium transients in Fig 6. by Maureen M. Sampson (9322886)

“…<p>Visually induced calcium transients were recorded in 5-HT2B +/- or 5-HT2B -/- flies as described in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1009003#pgen.1009003.g006" target="_blank">Fig 6</a>. …”

Effect of viable oral streptococci on the infectivity of IAV. by Nobuo Okahashi (409721)

Matrix-M Adjuvated Seasonal Virosomal Influenza Vaccine Induces Partial Protection in Mice and Ferrets against Avian H5 and H7 Challenge by Freek Cox (17922)

“…We demonstrate that mice were protected from death against challenges with H5N1 and H7N7, but that the protection was not complete as evidenced by severe clinical signs. …”

Single simulation illustrating trough-max and the switch to peak-max. by Austin E. Soplata (4676017)

The relationship of lung function with ambient temperature by Joseph M. Collaco (195530)

“…The effect was similar in both cohorts with a 0.71% and 0.59% predicted FEV₁ decrease for every 10°F increase in mean temperature in the NHANES III and NHANES 2007–2012 cohorts, respectively. …”

Nullclines in the <i>V</i>₂-<i>h</i> plane for fixed values of <i>V</i>₁ and trajectory of response to pair of EPSGs. by Joshua H. Goldwyn (339094)

“…In these simulations we set . The green trajectory is the response of the model to a pair of EPSGs with time delay of 1.5 ms and amplitude three times that of a unitary auditory nerve fiber input. …”

Morphometric analysis results of bone matrix staining after 5 days chemical treatments. by Jessica Aceto (752869)

“…<p>The distances are measured in pixels. Mean ± SD and t-test analysis were calculated for each measure on at least 20 individuals. * <i>p <</i> 0.05, ** <i>p <</i> 0.01 and ***<i>p <</i> 0.001. …”

Estimation of A3G and Vif production rates. by Iraj Hosseini (184245)

“…All the results in (A) and (B) are obtained for <i>k_A3G.HIV</i> = 50 µM⁻¹/hr. …”

Zebrafish Bone and General Physiology Are Differently Affected by Hormones or Changes in Gravity by Jessica Aceto (752869)

“…By combining morphometric tools with an objective scoring system for the state of development for each element in the head skeleton and specific gene expression analysis, we confirmed and characterized in detail the decrease or increase of bone formation caused by a 5 day treatment (from 5dpf to 10 dpf) of, respectively parathyroid hormone (PTH) or vitamin D3 (VitD3). …”