Image_6_C5a/C5aR1 Pathway Is Critical for the Pathogenesis of Psoriasis.JPEG by Quan-you Zheng (713217)

“…The lack of characterization of the pathogenesis of psoriasis has hindered efficient clinical treatment of the disease. In our study, we observed that expression of complement component 5a receptor 1(C5aR1) was significantly increased in skin lesions of both imiquimod (IMQ) and IL23-induced psoriatic mice and patients with psoriasis. …”

Toxicological Profile of Ultrapure 2,2′,3,4,4′,5,5′-Heptachlorbiphenyl (PCB 180) in Adult Rats by Matti Viluksela (321291)

“…Using a loading dose/maintenance dose regimen, groups of 5 males and 5 females were given total doses of 0, 3, 10, 30, 100, 300, 1000 or 1700 mg PCB 180/kg body weight by gavage. …”

<b>Wind speed manipulation experimental data from the Community Land Model version 5 (CLM5)</b> by Haohao Wu (18243244)

“…Then, experimental simulations were conducted using CLM5 for varying wind speed scenarios for the period of 1983 – 2014, including:</p><p dir="ltr">i) Control run: The simulation was forced by the default air forcing dataset of CLM5 – CRUNCEP version 7 meteorological data (6-hourly data; https://rda.ucar.edu/datasets), except for wind speed, which was replaced by data from the CRU JRA version 2.2 dataset, because the CRUNCEP7 wind speed revealed widespread increasing trend of terrestrial wind speed during 1983 – 2014, inconsistent with observations; in contrast, CRU JRA2.2 wind speed showed overall decreasing trend of terrestrial wind speed during the same period. …”

A Critical Role of the Thy28-MYH9 Axis in B Cell-Specific Expression of the <i>Pax5</i> Gene in Chicken B Cells by Toshitsugu Fujita (25023)

“…Loss-of-function of Thy28 induced decrease in Pax5 expression and recruitment of myosin-9 (MYH9), one of Thy28-interacting proteins, to the <i>Pax5</i> 1A promoter. …”

Image_5_Mouse models of lung-specific SARS-CoV-2 infection with moderate pathological traits.pdf by Sung-Hee Kim (11271393)

“…After inoculation of 10⁵ PFU of SARS-CoV-2 to the K18-hACE2, SFTPB-hACE2, and SCGB1A1-hACE2 models, the peak viral titer was detected at 2 days post-infection and then gradually decreased. …”

Image_5_Mouse models of lung-specific SARS-CoV-2 infection with moderate pathological traits.pdf by Sung-Hee Kim (11271393)

“…After inoculation of 10⁵ PFU of SARS-CoV-2 to the K18-hACE2, SFTPB-hACE2, and SCGB1A1-hACE2 models, the peak viral titer was detected at 2 days post-infection and then gradually decreased. …”

Data_Sheet_1_Impact of Coinfection With SARS-CoV-2 and Influenza on Disease Severity: A Systematic Review and Meta-Analysis.docx by Zhou Guan (3723796)

“…<p>Background: Although coinfection with influenza in COVID-19 patients has drawn considerable attention, it is still not completely understood whether simultaneously infected with these two viruses influences disease severity. We therefore aimed to estimate the impact of coinfected with SARS-CoV-2 and influenza on the disease outcomes compared with the single infection of SARS-CoV-2.…”

Stability of H9N2 M1 protein in DF1 cells. by Chenxi Wang (284364)

A comparison of METH or AMP brain and serum concentrations over time, after a 0.56 mg/kg <i>ip</i> injection of METH, between AAV-scFv6H4, AAV-scFv7F9, and a saline control at day... by Charles E. Hay (5470526)

The Natural Anticancer Agent Plumbagin Induces Potent Cytotoxicity in MCF-7 Human Breast Cancer Cells by Inhibiting a PI-5 Kinase for ROS Generation by Ju-Hee Lee (135452)

“…In MCF7 human breast cancer cells, plumbagin significantly decreased the level of a human ortholog, 1, 4-phopshatidylinositol 5-kinase (PI5K)-1B, of yeast its3, and knockdown of PI5K-1B using siPI5K-1B increased the ROS level and decreased cell viability. …”

Uncoupling protein-2 is an antioxidant that is up-regulated in the enamel organ of fluoride-treated rats by Maiko Suzuki (8794223)

“…Vitamin E is an antioxidant so we asked if a diet high in vitamin E would attenuate dental fluorosis. …”

M1 protein with T37A mutation confers increased pathogenicity and replication of H9N2 virus in mice. by Chenxi Wang (284364)

Epac activation increased RLC phosphorylation via PLC/PKC. by Yoshiki Ohnuki (576298)

Discovery of D25, a Potent and Selective MNK Inhibitor for Sepsis-Associated Acute Spleen Injury by Qiang Li (8118)

“…This study undertakes the modification of a 4-(3-(piperidin-4-yl)-1<i>H</i>-pyrazol-5-yl)pyridine structure, leading to the discovery of 4-(3-(piperidin-4-yl)-1<i>H</i>-pyrazol-5-yl)-1<i>H</i>-pyrrolo[2,3-<i>b</i>]pyridine (D25) as a potent and selective MNK inhibitor. …”

YorkU.forest.Oct5-2016 by Amrit Virdi (3130035)

“…</p><p><b>Abundance.woody.plants: </b>The total number of individual woody plants located within 0.5 meters of the 50m transect tape. A woody plant was defined as a tree that was over 1.5m in height. …”

M1-37T protein is degraded in a lysosome-independent manner, and its ubiquitination is not through K48 linkage. by Chenxi Wang (284364)

M1 protein harboring T37 is susceptible to ubiquitination at K187. by Chenxi Wang (284364)

T37A mutation protects M1 protein of BJ/3/99 virus from degradation directed by PKG and increases the viral replication. by Chenxi Wang (284364)

Stability of the H9N2 M1 protein of BJ/3/99 virus is increased by the T37A mutation. by Chenxi Wang (284364)

The stability of H9N2 M1 protein is increased by the replacement of T37 with A37. by Chenxi Wang (284364)