Image_2_Downregulation of miR-181b-5p Inhibits the Viability, Migration, and Glycolysis of Gallbladder Cancer by Upregulating PDHX Under Hypoxia.jpeg by Yiyu Qin (596247)

“…GBC cell viability was significantly decreased under hypoxia, and these decreases were exacerbated by miR-181b-5p antagomir. …”

DataSheet1_Zebrafish EEG predicts the efficacy of antiepileptic drugs.pdf by Jun-Nyeong Shin (14234054)

“…Moreover, the 50% effective doses (ED50) of valproate acid and tiagabine were determined based on zebrafish EEG for the first time, indicating that the quantitative inter-species comparison of the AED efficacy is possible between zebrafish and mammals such as rodents.…”

The effects of metformin, donepezil, insulin glargine, and glibenclamide on serum biomarkers: Glucose, HbA1c, lipid profile, IL6, TNFa, amyloid β 42, total plasma tau, and NFL. by Shatw Khalid Ali (13020885)

Table5_Linkage Disequilibrium and Effective Population Size of Buffalo Populations of Iran, Turkey, Pakistan, and Egypt Using a Medium Density SNP Array.XLSX by Shirin Rahimmadar (11801645)

Punicalagin ameliorates lipopolysaccharide-induced inflammatory response in dental pulp cells via inhibition of the NF-κB/Wnt5a-ROR2 pathway by Yumeng Yang (8155002)

“…</p> <p>PCG demonstrated an anti-inflammatory effect in LPS-induced DPCs by targeting the NF-κB/Wnt5a-ROR2 signaling pathway.</p> <p></p> <p>This schematic illustration demonstrates that PCG ameliorates LPS-elicited pulpitis by decreasing the expression of the proteins associated with the NF-κB signaling pathway and its downstream Wnt5a/ROR2 pathway and by reducing the production of inflammatory molecules.…”

Video5_The microglial innate immune receptor TREM2 participates in fear memory formation through excessive prelimbic cortical synaptic pruning.mp4 by Le-le Zhang (477674)

Table_5_Metagenomic Next-Generation Sequencing in the Diagnosis of HHV-1 Reactivation in a Critically Ill COVID-19 Patient: A Case Report.XLSX by Lei Shi (8144)

Image5_Linkage Disequilibrium and Effective Population Size of Buffalo Populations of Iran, Turkey, Pakistan, and Egypt Using a Medium Density SNP Array.PNG by Shirin Rahimmadar (11801645)

Image_5_Species identity and combinations differ in their overall benefits to Astragalus adsurgens plants inoculated with single or multiple endophytic fungi under drought conditio... by Yi-Ling Zuo (6943376)

Image_5_Increased atherosclerotic plaque in AOC3 knock-out in ApoE−/− mice and characterization of AOC3 in atherosclerotic human coronary arteries.tiff by Anna Filip (13776673)

Table5_Use of non-specific immunoglobulins in Catalonia in three third-level hospitals: a descriptive analysis of a hospital-prescribed medication registry.docx by J. Riera-Arnau (20431328)

Table_5_A Network-Based Method for Mechanistic Investigation and Neuroprotective Effect on Post-treatment of Senkyunolid-H Against Cerebral Ischemic Stroke in Mouse.XLSX by Jie Zhang (64655)

Image_2_JAK2V617F Mutation Promoted IL-6 Production and Glycolysis via Mediating PKM1 Stabilization in Macrophages.tif by Rongqing Li (2253712)

“…We, therefore, established JAK2^V617F-expressing murine macrophages (JAK2^V617F macrophages) and found that the levels of p-STAT3 were markedly elevated in JAK2^V617F macrophages in association with an increase in IL-6 production. …”

Circular RNA circ_0003028 contributes to tumorigenesis by regulating GOT2 via miR-1298-5p in non-small cell lung cancer by Hongjun Guan (4840134)

“…The biological role of circ_0003028 on NSCLC tumor growth was examined by the xenograft tumor model <i>in vivo</i>. We reported that circ_0003028 and GOT2 were upregulated, and miR-1298-5p was decreased in NSCLC tissues and cells. …”

Image_1_Comprehensive Proteomic Profiling of Urinary Exosomes and Identification of Potential Non-invasive Early Biomarkers of Alzheimer’s Disease in 5XFAD Mouse Model.tif by Zhiqi Song (8684007)

“…</p>Objective<p>To investigate the potential non-invasive early biomarkers of AD in 5XFAD mouse model, we investigate the proteome of urinary exosomes present in 1-month-old (before amyloid-β accumulation) 5XFAD mouse models and their littermate controls. …”

Image_1_JAK2V617F Mutation Promoted IL-6 Production and Glycolysis via Mediating PKM1 Stabilization in Macrophages.tif by Rongqing Li (2253712)

“…We, therefore, established JAK2^V617F-expressing murine macrophages (JAK2^V617F macrophages) and found that the levels of p-STAT3 were markedly elevated in JAK2^V617F macrophages in association with an increase in IL-6 production. …”

Table_5_Liraglutide Inhibits Osteoclastogenesis and Improves Bone Loss by Downregulating Trem2 in Female Type 1 Diabetic Mice: Findings From Transcriptomics.docx by Jie Yu (150626)

Table_5_Dietary supplementation of squalene increases the growth performance of early-weaned piglets by improving gut microbiota, intestinal barrier, and blood antioxidant capacity... by Yang Gao (18005)

“…The villus height (P < 0.001) and V/C ratio (villus height/crypt depth, P < 0.001) of the jejunum were significantly increased in the SQ group, while the crypt depth (P < 0.01) was decreased compared to the CON group. …”

Image5_Fatty acid metabolism prognostic signature predicts tumor immune microenvironment and immunotherapy, and identifies tumorigenic role of MOGAT2 in lung adenocarcinoma.tif by Denggang Fu (5082062)

“…However, studies on its impact in lung adenocarcinoma (LUAD) are limited.</p>Methods<p>We developed a prognostic signature comprising 10 FAM-related genes (GPR115, SOAT2, CDH17, MOGAT2, COL11A1, TCN1, LGR5, SLC34A2, RHOV, and DKK1) using data from LUAD patients in The Cancer Genome Atlas (TCGA). …”

Effect of ELX-02 in <i>CTNS</i>^{<i>Y226X/Y226X</i>} mice. by Emma J. Brasell (8081969)

“…<p><b>A</b>. Half-cystine measurements show decrease pathologic accumulation in kidneys of <i>Ctns</i>^{<i>Y226X/Y226X</i>} mice treated with 7 injections of ELX-02 (10 mg/kg) over a 3-week period. …”