Table_1_Preclinical characterization of amubarvimab and romlusevimab, a pair of non-competing neutralizing monoclonal antibody cocktail, against SARS-CoV-2.docx by Yun Ji (464484)

“…However, the continuous virus evolution requires diverse mAb options to combat variants. Here we describe two fully human mAbs, amubarvimab (BRII-196) and romlusevimab (BRII-198) that bind to non-competing epitopes on the receptor binding domain (RBD) of spike protein and effectively neutralize SARS-CoV-2 variants. …”

Table_5_NOTCH1 mutation associates with impaired immune response and decreased relapse-free survival in patients with resected T1-2N0 laryngeal cancer.docx by Xiao-yang Gong (13103400)

“…A total of 469 genomic alterations were detected in 211 distinct cancer-relevant genes, and the genes found to be mutated in more than five patients (>10%) included tumor protein p53 (TP53, 78.5%), FAT atypical cadherin 1 (FAT1, 26%), LDL receptor related protein 1B (LRP1B, 19%), cyclin dependent kinase inhibitor 2A (CDKN2A, 17%), tet methylcytosine dioxygenase 2 (TET2, 17%), notch receptor 1 (NOTCH1, 12%) and neuregulin 1 (NRG1, 12%). …”

Chromosomal Translocations in the Parasite <i>Leishmania</i> by a MRE11/RAD50-Independent Microhomology-Mediated End Joining Mechanism by Marie-Claude N. Laffitte (669627)

“…Sequencing data also showed a decreased coverage at subtelomeric locations in many chromosomes in the <i>MRE11</i>^<i>-/-</i><i>RAD50</i>^<i>-/-</i> parasites. …”

Training impact on electrical properties of P3 lumbar MNs. Rin: input resistance. Rheobase: lowest intensity of current injected in MNs to elicit an action potential (AP). AP threshold: voltage measured at the foot of the AP. AP amplitude: measured between the resting membrane potential and the AP peak. AP half width: time spent by the potential > 50% of the AP maximum amplitude. AP rise time: time spent by the potential between 10% and 90% of the AP maximum amplitude. AP half decay time: time spent by the potential between the AP maximum amplitude and the 50% decreasing amplitude. ADP: after-depolarization potential.... by Camille Quilgars (21156495)

“…AP half decay time: time spent by the potential between the AP maximum amplitude and the 50% decreasing amplitude. ADP: after-depolarization potential. …”

Tyro 3 overexpression decreases the production of Aβ from 293APPswe cells and Gas6 inhibits the effect in a concentration-dependent manner. by Yan Zheng (61178)

“…(D) ELISA assay shows that a decrease in Aβ in Tyro-3-transfected 293APPswe cells relative to the GFP transfected controls. …”

Characteristics of patients with AKI diagnosed using eKDIGO only by the decrease in sCr (deKDIGO) and no AKI. by Marina Wainstein (12437091)

Pictorial view of some highly poisonous plants based on their LD50 values and respondent scores. by Faisal Rasool (12530732)

DA receptor agonist pramipexole reduces generosity reference-point (V). by Sergio Oroz Artigas (8207559)

Simulations that now also include an <i>asymmetric</i> indoors/outdoors model, with a threshold temperature of 17.5C in spring, and 25C in fall. by Sebastian A. Müller (10688740)

Serves as the data source for Fig 5. by Shuai Huang (60512)

Tetrahydrohyperforin Inhibits the Proteolytic Processing of Amyloid Precursor Protein and Enhances Its Degradation by Atg5-Dependent Autophagy by Viviana A. Cavieres (500139)

“…To investigate the contribution of autophagy, we tested the effect of IDN5706 in Atg5-depleted cells. …”

RNA sequencing linkage analysis identifies a single base pair change on Chromosome 25 that is tightly linked to the <i>escapist</i> hypersensitive phenotype. by Elelbin A. Ortiz (8655285)

A Minor (<50%) Signet-Ring Cell Component Associated with Poor Prognosis in Colorectal Cancer Patients: A 26-Year Retrospective Study in China by Yinuo Tan (705777)

“…<div><p>Background</p><p>We performed a retrospective study to determine the cancer-specific survival of colorectal cancer patients with a component of signet-ring cells or mucin comprising < 50% of the tumor mass.…”

Top 50 up-regulated genes in <i>lin-35(n745</i>), mutant in starved L1 animals. by Ashwin Seetharaman (615458)

Additional images of Rad50 and Mre11 colocalization with replicating viral DNA during PCNA-I1 inhibition. by Jessica E. Packard (16641690)

Detoxifying enzyme activities of slug larvae and adults treated with LC₅₀ for 24 and 48 h, respectively. by Haojun Li (11007721)

Protective enzyme activities of slug larvae and adults treated with LC₅₀ for 24 and 48 h, respectively. by Haojun Li (11007721)

Data Sheet 1_Reduced hemolytic complement activity in the classical pathway (CH50) is a risk factor for poor clinical outcomes of patients with infections: a retrospective analysis... by Hiroyuki Koami (3878434)

“…</p>Results<p>Of 2,726 patients who met the inclusion criteria, logistic regression models demonstrated that decreased CH50 is a significant predictor of 180-day mortality (OR: 0.98-0.99). …”

A Dietary Supplement Containing Cinnamon, Chromium and Carnosine Decreases Fasting Plasma Glucose and Increases Lean Mass in Overweight or Obese Pre-Diabetic Subjects: A Randomized... by Yuejun Liu (800012)

“…</p><p>Results</p><p>Four-month treatment with the dietary supplement decreased FPG compared to placebo (-0.24±0.50 <i>vs</i> +0.12±0.59 mmol/L, respectively, p = 0.02), without detectable significant changes in HbA1c. …”

DataSheet_1_Imiquimod Boosts Interferon Response, and Decreases ACE2 and Pro-Inflammatory Response of Human Bronchial Epithelium in Asthma.pdf by Juan José Nieto-Fontarigo (11800142)

“…Background<p>Both anti-viral and anti-inflammatory bronchial effects are warranted to treat viral infections in asthma. We sought to investigate if imiquimod, a TLR7 agonist, exhibits such dual actions in ex vivo cultured human bronchial epithelial cells (HBECs), targets for SARS-CoV-2 infectivity.…”