Intranasal NIC-hLYS is efficacious in vivo against MERS-CoV. by Ashlee D. Brunaugh (4263472)

“…<p>The efficacy of NIC-hLYS particles was assessed in a lethal SARS-CoV-2 infection model (A). Once daily intranasal administration of NIC-hLYS particles suspended in 0.45% sodium chloride resulted in 30% survival in a lethal SARS-CoV-2 infection (B) and produced a statistically significant decrease in lung viral titers after 10 days of dosing (C). …”

Comparisons were made between two groups of 2, 3 or 5 replicates by Dietmar E Martin (5143)

“…</p> The first group is composed of synthetic data sets made from the experimental replicates Wt-t0a and Wt-t0b, in which 1000 genes (500 increased and 500 decreased) are changed (p…”

Pre-ART plasma barcode proportion during primary infection. by Brandon F. Keele (7450001)

Histological abnormalities in E18.5 ATF2 mutant cerebellum and brainstem. by Julien Ackermann (223933)

“…Number of hypoglossal motoneurons (h) is bilaterally decreased in <i>Atf2^−/−</i> embryos while number of dorsal vagal motoneurons (v) appears normal. …”

The phenotype of <i>Ttbk2</i>^{<i>sca11/sca11</i>} embryos is identical to that of the null allele. by Emily Bowie (543704)

Characteristics of study subjects. by Bi Xue Patricia Soh (21100364)

“…Upon TID adjustment, the percentage of vegans meeting adequacy for protein and IAA decreased and only approximately 50% of the cohort could meet lysine and leucine requirements. …”

Fig 4 - by Xiu-Qi Chen (13832389)

“…NETs in gastric tissues. Scale label 50 μm. NETs were observed in IgAV model group and decreased in DNase I intervention group but absent in control group. …”

Fig 5 - by Xiu-Qi Chen (13832389)

Sinus nodal action potential (spontaneous sinus rate). by Manabu Murakami (1786186)

“…TRIC-A^–/–SA nodes showed a decreased response. <i>n</i> = 5–6. <i>P</i> < 0.05. …”

Ca²⁺ supplementation <i>in vitro</i> increases cell death in polarized human macrophages and favours an M1 phenotype. by Yusuf Cem Eskiocak (10789281)

TBM on high resolution ex vivo T₂-weighted MR images. by Ivan Rattray (399247)

“…A more defined sub-regional pattern of statstical differences between WT and <i>Hdh</i>Q150 was evidence using this approach. …”

Determining the role of missense mutations in the POU domain of HNF1A that reduce the DNA-binding affinity: A computational approach by P., Sneha

“…Triplicate runs of molecular dynamic (MD) simulations (50ns) revealed smaller changes in patterns of deviation, fluctuation, and compactness, in complexes containing the R131Q and R131W mutations, compared to complexes containing the R203C mutant complex. …”
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Loss of Sirt3 in BMCs increases apoptosis in post-MI mice. by Heng Zeng (324703)

Effect of BPA on CYP450s expression, and nicotine modulation, in fetal rat brain by Mohammad H., Merii

“…Fetal brains were isolated at gestational days GD14 and GD19, and protein expression was assessed by Western blotting. Results showed a BPA-induced significant decrease in CYP1B1 expression levels at GD14 (p = 0.001), and CYP19A1 (aromatase) expression at both mid- and late-stage development (p < 0.001). …”
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Binding analysis of typical ligands for T1rs to T1r2a/T1r3LBD. by Hikaru Ishida (18239420)

DDX5 and DDX17 are required for EBV lytic reactivation. by Praneet Kaur Sandhu (21156149)

Analysis of proliferation in NBs depleted of Opa1 and Marf. by Dnyanesh Dubal (12085942)

De-identified dataset. by Zeshan A. Chisty (18388200)

“…</p><p>Results</p><p>The median age of the 37 participants at enrollment was 70.5 years; 30 (81%) had prior SARS-CoV-2 infection, and 76% received Pfizer-BioNTech and 24% Moderna homologous vaccines. …”

A flowchart describes the stepwise analysis of missense SNPs in the human PC and illustrates the computational tools used in the study. by Mahvash Farajzadeh-Dehkordi (17468232)

Spontaneous glutamate transients and neuronal activity after blockade of specific pathways of glutamate transport and release. by Saju Balakrishnan (58265)