Characterization of cell death signaling downstream of IKK blockade in human macrophages. by Neha M. Nataraj (19485995)

Developmentally regulated promoter-switch transcriptionally controls function during embryonic hematopoiesis-5 by Amir Pozner (78042)

“…Shown are average numbers of colonies per FL ± S.E. of at least three different WT or P2embryos at E12.5 and E13.5. The difference between WT and P2colony number is significant (*) at P < 0.001 by Student's t test. …”

Sera from vaccinated mice partially cross-neutralized SARS-CoV-2 variants of concern. by Rakesh Kulkarni (1464784)

“…The dotted line represents assay limit of detection. # represents n = 3. ns-not significant. <b>(B-D).</b> Fold decrease for immunized sera from MVA5/MVA1 (B), vNY1/MVA1(C) and vNY5/MVA1(D) vaccination regimens in neutralization assays of individual variants relative to WT pseudovirus. …”

The mutagenicity of K₂CrO₄ in human TK6 cells is markedly decreased by reducing K₂CrO₄ incubation time. by Xu Tian (179192)

Localization of IFT proteins is perturbed in <i>Ttbk2</i> hypomorphic alleles. by Emily Bowie (543704)

Box and whisker plots of the VSD and VDI distribution in the tertiary referral centers (Cohort 1). by Sam Kushner-Lenhoff (12003804)

Supplementary Table 1 - Additional PSD Results by David Aguilar (7148330)

“…</b>Arrows represent a significant increase (↑) or decrease (↓) in normalized mGluR5 KO spectral power compared to WT controls in the same condition. …”

GFP-LL5β(381–510) inhibits tumor cell invasion. by Lucrezia Maria Ribolla (16535119)

“…(<b>D</b>) Clones of MDA-MB-231 cells expressing the indicated GFP-tagged proteins were used for transwell Matrigel invasion assays: invasion is significantly decreased for cells expressing GFP-LL5β(381–510), but not for cells expressing either GFP or GFP-LL5β(305–450). …”

Targeted quantification of Na⁺, Cl^-, S and Mg²⁺ in the cytosol, mitochondria, condensed chromatin and nucleoplasm. by Frédérique Nolin (2151472)

Targeted quantification of water and of N, P and K⁺ in the cytosol, mitochondria, condensed chromatin and nucleoplasm. by Frédérique Nolin (2151472)

Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery by Pasquale Linciano (4426435)

“…In particular, compound <b>4m</b>, a biphenyl-thiadiazole-2,5-diamine with IC₅₀ = 16 μM, was able to potentiate the antitrypanosomal activity of the dihydrofolate reductase inhibitor methotrexate (MTX) with a 4.1-fold decrease of the EC₅₀ value. …”

Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery by Pasquale Linciano (4426435)

“…In particular, compound <b>4m</b>, a biphenyl-thiadiazole-2,5-diamine with IC₅₀ = 16 μM, was able to potentiate the antitrypanosomal activity of the dihydrofolate reductase inhibitor methotrexate (MTX) with a 4.1-fold decrease of the EC₅₀ value. …”

Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery by Pasquale Linciano (4426435)

“…In particular, compound <b>4m</b>, a biphenyl-thiadiazole-2,5-diamine with IC₅₀ = 16 μM, was able to potentiate the antitrypanosomal activity of the dihydrofolate reductase inhibitor methotrexate (MTX) with a 4.1-fold decrease of the EC₅₀ value. …”

Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery by Pasquale Linciano (4426435)

“…In particular, compound <b>4m</b>, a biphenyl-thiadiazole-2,5-diamine with IC₅₀ = 16 μM, was able to potentiate the antitrypanosomal activity of the dihydrofolate reductase inhibitor methotrexate (MTX) with a 4.1-fold decrease of the EC₅₀ value. …”

Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery by Pasquale Linciano (4426435)

“…In particular, compound <b>4m</b>, a biphenyl-thiadiazole-2,5-diamine with IC₅₀ = 16 μM, was able to potentiate the antitrypanosomal activity of the dihydrofolate reductase inhibitor methotrexate (MTX) with a 4.1-fold decrease of the EC₅₀ value. …”

Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery by Pasquale Linciano (4426435)

“…In particular, compound <b>4m</b>, a biphenyl-thiadiazole-2,5-diamine with IC₅₀ = 16 μM, was able to potentiate the antitrypanosomal activity of the dihydrofolate reductase inhibitor methotrexate (MTX) with a 4.1-fold decrease of the EC₅₀ value. …”

Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery by Pasquale Linciano (4426435)

“…In particular, compound <b>4m</b>, a biphenyl-thiadiazole-2,5-diamine with IC₅₀ = 16 μM, was able to potentiate the antitrypanosomal activity of the dihydrofolate reductase inhibitor methotrexate (MTX) with a 4.1-fold decrease of the EC₅₀ value. …”

Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery by Pasquale Linciano (4426435)

“…In particular, compound <b>4m</b>, a biphenyl-thiadiazole-2,5-diamine with IC₅₀ = 16 μM, was able to potentiate the antitrypanosomal activity of the dihydrofolate reductase inhibitor methotrexate (MTX) with a 4.1-fold decrease of the EC₅₀ value. …”

Ciliary defects are evident in <i>Ttbk2</i> hypomorphic mutant cells. by Emily Bowie (543704)

Structure-function correlation of the central retina in a patient with X-linked retinoschisis (upper panels) and a patient with Usher syndrome 2A (lower panels). by Peter Charbel Issa (241475)

“…Only the most distinct alterations result in a relative scotoma (10 dB decreased light intensity compared to the brightest stimulus). …”