Search alternatives:
ns decrease » nn decrease (Expand Search), _ decrease (Expand Search), we decrease (Expand Search)
wt decrease » we decrease (Expand Search), _ decrease (Expand Search), nn decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
ns decrease » nn decrease (Expand Search), _ decrease (Expand Search), we decrease (Expand Search)
wt decrease » we decrease (Expand Search), _ decrease (Expand Search), nn decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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14421
Presentation_2_Constructing a prognostic risk model for Alzheimer’s disease based on ferroptosis.pdf
Published 2023“…Moreover, RT-qPCR showed that with the increase of Aβ<sub>1–42</sub> concentration, the expression of POR decreased first and then increased; RUFY3 was firstly increased and then decreased.…”
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14422
Metabolic effects of exposure to AmB in <i>L</i>. <i>mexicana</i> promastigotes cultured in HOMEM and DM.
Published 2022“…Each line represents one biological replicate (n = 4). Increase (red) or decrease (blue) in fold-change is relative to untreated cells after treatment with AmB at 5 x their EC<sub>50</sub> values for 15 mins. …”
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14423
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14424
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14425
Data_Sheet_1_The Modulatory Role of CYP3A4 in Dictamnine-Induced Hepatotoxicity.docx
Published 2018“…Contrarily, the cytotoxicity was decreased in CYP3A4-inhibited PHH and CYP3A4 OE HepG2 and L02 cells inhibited by ketoconazole (KTZ). …”
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14426
Parthenolide Derivatives as PKM2 Activators Showing Potential in Colorectal Cancer
Published 2021“…In this study, we designed a series of parthenolide (PTL) derivatives through a stepwise structure optimization, and an excellent derivate <b>29e</b> showed good activity on PKM2 (AC<sub>50</sub> = 86.29 nM) and displayed significant antiproliferative activity against HT29 (IC<sub>50</sub> = 0.66 μM) and SW480 (IC<sub>50</sub> = 0.22 μM) cells. …”
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14427
Parthenolide Derivatives as PKM2 Activators Showing Potential in Colorectal Cancer
Published 2021“…In this study, we designed a series of parthenolide (PTL) derivatives through a stepwise structure optimization, and an excellent derivate <b>29e</b> showed good activity on PKM2 (AC<sub>50</sub> = 86.29 nM) and displayed significant antiproliferative activity against HT29 (IC<sub>50</sub> = 0.66 μM) and SW480 (IC<sub>50</sub> = 0.22 μM) cells. …”
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14428
Parthenolide Derivatives as PKM2 Activators Showing Potential in Colorectal Cancer
Published 2021“…In this study, we designed a series of parthenolide (PTL) derivatives through a stepwise structure optimization, and an excellent derivate <b>29e</b> showed good activity on PKM2 (AC<sub>50</sub> = 86.29 nM) and displayed significant antiproliferative activity against HT29 (IC<sub>50</sub> = 0.66 μM) and SW480 (IC<sub>50</sub> = 0.22 μM) cells. …”
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14429
Parthenolide Derivatives as PKM2 Activators Showing Potential in Colorectal Cancer
Published 2021“…In this study, we designed a series of parthenolide (PTL) derivatives through a stepwise structure optimization, and an excellent derivate <b>29e</b> showed good activity on PKM2 (AC<sub>50</sub> = 86.29 nM) and displayed significant antiproliferative activity against HT29 (IC<sub>50</sub> = 0.66 μM) and SW480 (IC<sub>50</sub> = 0.22 μM) cells. …”
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14430
Parthenolide Derivatives as PKM2 Activators Showing Potential in Colorectal Cancer
Published 2021“…In this study, we designed a series of parthenolide (PTL) derivatives through a stepwise structure optimization, and an excellent derivate <b>29e</b> showed good activity on PKM2 (AC<sub>50</sub> = 86.29 nM) and displayed significant antiproliferative activity against HT29 (IC<sub>50</sub> = 0.66 μM) and SW480 (IC<sub>50</sub> = 0.22 μM) cells. …”
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14431
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14432
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14433
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14434
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14435
An Allosteric Modulator of RNA Binding Targeting the N‑Terminal Domain of TDP-43 Yields Neuroprotective Properties
Published 2020“…<i>In silico</i> docking of 50K compounds to the NTD domain of TDP-43 identified a small molecule (nTRD22) that is bound to the N-terminal domain. …”
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14436
The number of amyloid plaques and amount of Aβ<sub>1-42</sub> were reduced in S100A9 KO/Tg mice.
Published 2014“…Sections are 4 µm thick. ((a) – (h) Scale bar; 200 µm, (i)-(l) scale bar; 50 µm). …”
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14437
MDS erythroid precursors are deficient in membrane lipid rafts.
Published 2014“…Enlarged images illustrate lipid rafts at 630x with 6-zoom magnification. Bars represent 5 µm. (B) Statistically significant decrease in the number of rafts per cell in MDS erythroid precursors compared to normal donor erythroid cells, graph represents mean ± SE. …”
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14438
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14439
Antimicrobial activity of RP-1 peptide conjugate with ferrocene group
Published 2020“…In comparison with amphotericin B, a second-line drug approved for leishmaniasis treatment, (IC<sub>50</sub> = 0.63 μmol L<sup>-1</sup>), Fc-RP1 was more active and showed a 2.5-fold higher selectivity index. …”
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14440