Showing 14,421 - 14,440 results of 46,970 for search '(( 50 ((ns decrease) OR (a decrease)) ) OR ( 5 ((wt decrease) OR (mean decrease)) ))', query time: 1.31s Refine Results
  1. 14421

    Presentation_2_Constructing a prognostic risk model for Alzheimer’s disease based on ferroptosis.pdf by Xiao-Li Wang (182636)

    Published 2023
    “…Moreover, RT-qPCR showed that with the increase of Aβ<sub>1–42</sub> concentration, the expression of POR decreased first and then increased; RUFY3 was firstly increased and then decreased.…”
  2. 14422

    Metabolic effects of exposure to AmB in <i>L</i>. <i>mexicana</i> promastigotes cultured in HOMEM and DM. by Edubiel A. Alpizar-Sosa (13848145)

    Published 2022
    “…Each line represents one biological replicate (n = 4). Increase (red) or decrease (blue) in fold-change is relative to untreated cells after treatment with AmB at 5 x their EC<sub>50</sub> values for 15 mins. …”
  3. 14423
  4. 14424
  5. 14425

    Data_Sheet_1_The Modulatory Role of CYP3A4 in Dictamnine-Induced Hepatotoxicity.docx by Zhuo-Qing Li (4455073)

    Published 2018
    “…Contrarily, the cytotoxicity was decreased in CYP3A4-inhibited PHH and CYP3A4 OE HepG2 and L02 cells inhibited by ketoconazole (KTZ). …”
  6. 14426

    Parthenolide Derivatives as PKM2 Activators Showing Potential in Colorectal Cancer by Xingchen Liu (524190)

    Published 2021
    “…In this study, we designed a series of parthenolide (PTL) derivatives through a stepwise structure optimization, and an excellent derivate <b>29e</b> showed good activity on PKM2 (AC<sub>50</sub> = 86.29 nM) and displayed significant antiproliferative activity against HT29 (IC<sub>50</sub> = 0.66 μM) and SW480 (IC<sub>50</sub> = 0.22 μM) cells. …”
  7. 14427

    Parthenolide Derivatives as PKM2 Activators Showing Potential in Colorectal Cancer by Xingchen Liu (524190)

    Published 2021
    “…In this study, we designed a series of parthenolide (PTL) derivatives through a stepwise structure optimization, and an excellent derivate <b>29e</b> showed good activity on PKM2 (AC<sub>50</sub> = 86.29 nM) and displayed significant antiproliferative activity against HT29 (IC<sub>50</sub> = 0.66 μM) and SW480 (IC<sub>50</sub> = 0.22 μM) cells. …”
  8. 14428

    Parthenolide Derivatives as PKM2 Activators Showing Potential in Colorectal Cancer by Xingchen Liu (524190)

    Published 2021
    “…In this study, we designed a series of parthenolide (PTL) derivatives through a stepwise structure optimization, and an excellent derivate <b>29e</b> showed good activity on PKM2 (AC<sub>50</sub> = 86.29 nM) and displayed significant antiproliferative activity against HT29 (IC<sub>50</sub> = 0.66 μM) and SW480 (IC<sub>50</sub> = 0.22 μM) cells. …”
  9. 14429

    Parthenolide Derivatives as PKM2 Activators Showing Potential in Colorectal Cancer by Xingchen Liu (524190)

    Published 2021
    “…In this study, we designed a series of parthenolide (PTL) derivatives through a stepwise structure optimization, and an excellent derivate <b>29e</b> showed good activity on PKM2 (AC<sub>50</sub> = 86.29 nM) and displayed significant antiproliferative activity against HT29 (IC<sub>50</sub> = 0.66 μM) and SW480 (IC<sub>50</sub> = 0.22 μM) cells. …”
  10. 14430

    Parthenolide Derivatives as PKM2 Activators Showing Potential in Colorectal Cancer by Xingchen Liu (524190)

    Published 2021
    “…In this study, we designed a series of parthenolide (PTL) derivatives through a stepwise structure optimization, and an excellent derivate <b>29e</b> showed good activity on PKM2 (AC<sub>50</sub> = 86.29 nM) and displayed significant antiproliferative activity against HT29 (IC<sub>50</sub> = 0.66 μM) and SW480 (IC<sub>50</sub> = 0.22 μM) cells. …”
  11. 14431
  12. 14432
  13. 14433
  14. 14434
  15. 14435

    An Allosteric Modulator of RNA Binding Targeting the N‑Terminal Domain of TDP-43 Yields Neuroprotective Properties by Niloufar Mollasalehi (9511076)

    Published 2020
    “…<i>In silico</i> docking of 50K compounds to the NTD domain of TDP-43 identified a small molecule (nTRD22) that is bound to the N-terminal domain. …”
  16. 14436

    The number of amyloid plaques and amount of Aβ<sub>1-42</sub> were reduced in S100A9 KO/Tg mice. by Hee Jin Kim (469168)

    Published 2014
    “…Sections are 4 µm thick. ((a) – (h) Scale bar; 200 µm, (i)-(l) scale bar; 50 µm). …”
  17. 14437

    MDS erythroid precursors are deficient in membrane lipid rafts. by Kathy L. McGraw (327439)

    Published 2014
    “…Enlarged images illustrate lipid rafts at 630x with 6-zoom magnification. Bars represent 5 µm. (B) Statistically significant decrease in the number of rafts per cell in MDS erythroid precursors compared to normal donor erythroid cells, graph represents mean ± SE. …”
  18. 14438
  19. 14439

    Antimicrobial activity of RP-1 peptide conjugate with ferrocene group by Natalia C. S. Costa (8626206)

    Published 2020
    “…In comparison with amphotericin B, a second-line drug approved for leishmaniasis treatment, (IC<sub>50</sub> = 0.63 μmol L<sup>-1</sup>), Fc-RP1 was more active and showed a 2.5-fold higher selectivity index. …”
  20. 14440