Hedgehog Signaling Antagonist Promotes Regression of Both Liver Fibrosis and Hepatocellular Carcinoma in a Murine Model of Primary Liver Cancer by George M. Philips (206900)

“…Hepatocellular carcinoma (HCC) emerges spontaneously in such mice by 50–60 weeks of age, providing a model of fibrosis-associated hepatocarcinogenesis. …”

Table 1_Evaluating the prognostic relevance of neutrophil-to-lymphocyte ratio in cervical cancer: a systematic review and meta-analysis.docx by Xieyan Zhuang (20467625)

“…Furthermore, elevated NLR significantly impacted disease-free survival (HR: 1.79, 95% CI: 1.18-2.71; p = 0.006), recurrence rates (HR: 2.18, 95% CI: 1.36-3.51; p = 0.001), recurrence-free survival (HR: 3.05, 95% CI: 1.79-5.19; p < 0.0001), and the incidence of distant metastases (HR: 1.73, 95% CI: 1.20-2.50; p = 0.003).</p>Conclusion<p>An elevated NLR prior to treatment demonstrates a strong association with decreased OS and PFS among patients with cervical cancer, underscoring the significance of NLR as a prognostic marker within this population.…”

Modeling collisions in laying hens as a tool to identify causative factors for keel bone fractures and means to reduce their occurrence and severity by Michael Toscano (5497490)

“…<div><p>Keel fractures represent a major productivity and welfare issue for the laying hen industry with greater than 50% of birds in recent surveys across various commercial operations and nations exhibiting some form of damage by end of lay. …”

Data_Sheet_2_Effect of Levothyroxine on Blood Pressure in Patients With Subclinical Hypothyroidism: A Systematic Review and Meta-Analysis.doc by Weiwei He (32469)

“…Meta-analysis of the 19 prospective follow-up studies found that LT4 therapy significantly decreased SBP and DBP by 4.80 mmHg (95%CI −6.50 to −3.09, P < 0.001) and 2.74 mmHg (95%CI −4.06 to −1.43, P < 0.001), respectively.…”

Poly(caprolactone)-Based Coatings on 3D-Printed Biodegradable Implants: A Novel Strategy to Prolong Delivery of Hydrophilic Drugs by Sarah A. Stewart (9198984)

“…Implants could be specifically developed in order to match the specific release rate required for a number of drugs for a wide range of conditions.…”

Data_Sheet_1_Association of plasma propionate concentration with coronary artery disease in a large cross-sectional study.PDF by Nikolaos Pagonas (306007)

“…</p>Results<p>The study included 1,253 patients (median [IQR], 67 [58–76] years; 799 men [64%]). A total of 739 had invasively confirmed CAD with at least one coronary artery stenosis ≥50% and 514 had exclusion of CAD. …”

Dental developmental complications in pediatric hematopoietic stem cell transplantation patients: A study using CMC clinical data warehouse by Jaehyun Kim (14009967)

“…Regression analysis demonstrated that a younger age at initial chemotherapy was a risk factor for tooth agenesis and microdontia.  …”

Behavioural and Brain Gene Expression Profiling in Pigs during Tail Biting Outbreaks – Evidence of a Tail Biting Resistant Phenotype by Emma Brunberg (423126)

“…<div><p>Abnormal tail biting behaviour is a major welfare problem for pigs receiving the behaviour, as well as an indication of decreased welfare in the pigs performing it. …”

Data_Sheet_1_Effect of Levothyroxine on Blood Pressure in Patients With Subclinical Hypothyroidism: A Systematic Review and Meta-Analysis.docx by Weiwei He (32469)

“…Meta-analysis of the 19 prospective follow-up studies found that LT4 therapy significantly decreased SBP and DBP by 4.80 mmHg (95%CI −6.50 to −3.09, P < 0.001) and 2.74 mmHg (95%CI −4.06 to −1.43, P < 0.001), respectively.…”

Increased Drought Impacts on Temperate Rainforests from Southern South America: Results of a Process-Based, Dynamic Forest Model by Alvaro G. Gutiérrez (605525)

“…We compared the responses of a young stand (YS, ca. 60 years-old) and an old-growth forest (OG, >500 years-old) in the same area. …”

Serum Metabolic Signatures Induced By a Three-Day Intensified Exercise Period Persist After 14 h of Recovery in Runners by David C. Nieman (322662)

“…Immediately following the 3-day exercise period, significant 2-fold or higher increases in 75 metabolites were measured, with all but 22 of these metabolites related to lipid/carnitine metabolism, 13 to amino acid/peptide metabolism, 4 to hemoglobin/porphyrin metabolism, and 3 to Krebs cycle intermediates (<i>q</i>-values < 0.001). After a 14 h overnight recovery period, 50 of the 75 metabolites remained elevated, with 8 decreased (primarily amino acid-related metabolites) (<i>q</i>-values < 0.05). …”

Fig 12 - by Sana Khalid (132742)

Supplementary Material for: Association between Preoperative Monocyte-to-Lymphocyte Ratio and Late Arteriovenous Fistula Dysfunction in Hemodialysis Patients: A Cohort Study by Hu S. (5689703)

“…Association of preoperative MLR with AVF dysfunction (thrombosis or decrease of normal vessel diameter by >50%, requiring either surgical revision or percutaneous transluminal angioplasty) was assessed by multivariable Cox proportional hazard regression. …”

Mechanism of RPE Cell Death in α-Crystallin Deficient Mice: A Novel and Critical Role for MRP1-Mediated GSH Efflux by Parameswaran G. Sreekumar (176748)

“…On the other hand, cellular GSH was decreased by 50% in murine retina lacking αA or αB crystallin. …”

Data_Sheet_1_Stabilization of a Cart Inverted Pendulum: Improving the Intermittent Feedback Strategy to Match the Limits of Human Performance.pdf by Pietro Morasso (259809)

“…The difficulty of the task grows exponentially with the decrease of the length of the stick and a stick length of 32 cm is considered as a human limit even for well-trained subjects. …”

Table_1_A meta-analysis to examine whether nitrification inhibitors work through selectively inhibiting ammonia-oxidizing bacteria.docx by Jilin Lei (13115496)

“…The abundance of AOB amoA genes was dramatically reduced by about 50% with NI application in most soil types. …”

Table_1_A meta-analysis to examine whether nitrification inhibitors work through selectively inhibiting ammonia-oxidizing bacteria.xlsx by Jilin Lei (13115496)

“…The abundance of AOB amoA genes was dramatically reduced by about 50% with NI application in most soil types. …”

Can Supervised Pelvic Floor Muscle Training Through Gametherapy Relieve Urinary Incontinence Symptoms in Climacteric Women? A Feasibility Study by Anita Bellotto Leme Nagib (12726816)

“…Moreover, there was a concomitant increase in pelvic floor muscles (PFMs) power (2.0 to 3.0), repetition (3.0 to 5.0), and fast (10.0 to 10.0) in G_Game. …”

Data Sheet 1_The role of statins in dementia or Alzheimer’s disease incidence: a systematic review and meta-analysis of cohort studies.docx by Ye Du (4067569)

“…Similarly, an analysis of 19 studies comprising 1,237,341 participants demonstrated a 29% decrease in the risk of AD among statin users (HR: 0.71, 95% CI: 0.60–0.85). …”

Anharmonicity and Effect of the Nanostructuring on the Lattice Dynamics of CrSi₂ by A. Moll (9955135)

“…In addition, the GVDOS of nanocrystalline CrSi₂ evidences a spectral weight transfer at low energy, which is related to a decrease in both the Debye temperature and the sound velocities that may be ascribed to an increase in both the interface density and internal strain. …”