CRISPR <i>kcnk5b</i> KO strategy, targeting efficiency of endogenous locus and Kcnk5b mutants. by Xiaowen Jiang (8291814)

Effect of partial Glo-I inhibition by EP on LPS-induced production of TNF-α, collagen-I and α-SMA in HSC. by Marcus Hollenbach (376231)

“…Co-treatment of LPS and EP indicated significant dose-dependent reduction of LPS-induced markers of inflammation <b>(A1)</b> and fibrosis <b>(B1, C1)</b>. Presence of LPS and treatment with low-level concentrations of MGO (indicating partial inhibition of Glo-I activity without complete enzyme inhibition) showed significant decrease of LPS-induced release of TNF-α (absence vs. presence of 10mM MGO: 371.8±22.7 vs. 60.9±11.2 pg/ml; p<0.001), collagen-I (10.0±0.3 vs. 1.8±0.5 ng/ml; p<0.001) and α-SMA (68.6±3.6 vs. 43.8±2.2 ng/ml; p<0.001) <b>(A2, B2, C2)</b>. …”

Proteins in thyroid tissue with differential expression levels above or below 1.5 for all activity groups (0.5, 5, 50 and 500 kBq) (totally 133 proteins). by Malin Larsson (1616557)

“…Eight of these proteins were present in all four groups (ARF3, DLD, IKBKB, KTR4, NONO, RAB6A, RPN2 and SLC25A5). For the majority of proteins, the expression levels were ether increased or decreased for all activity levels.…”

Decreased hyper-resection in a NuA4 acetylation defective mutant in G1 and defect in DNA break repair by SSA. by Salar Ahmad (11457776)

“…(F) The <i>esa1-ts</i> mutation leads to a decrease of DSB repair by resection-based single-strand annealing. …”

Vitamin A Deficiency by Feng Chen (22082153)

Fig 5 - by Tiequan Niu (9927917)

Fig 5 - by Ananda de Mesquita Araújo (17775616)

Fig 5 - by Ferenc Tóth (665272)

Fig 5 - by Giulia Comunale (11570819)

S5 Data - by Jae Hwan Bong (17054738)

Fig 5 - by Ama tul Zahra (17941364)

Data_Sheet_1_MxB Disrupts Hepatitis C Virus NS5A–CypA Complex: Insights From a Combined Theoretical and Experimental Approach.PDF by Quanjie Li (447626)

“…A 28% decrease in CypA–NS5A binding affinity was observed in the presence of MxB, suggesting a weakened CypA–NS5A association upon binding of MxB to NS5A, which may contribute to the MxB-mediated inhibitory effect on the formation of CypA–NS5A complex. …”

Fig 5 - by Akshay Flora (17334104)

Fig 5 - by Yezhe Lin (5816036)

Fig 5 - by Abdulrahman Alshalani (14758273)

Fig 5 - by Onnicha Leelastwattanagul (17328305)

Fig 5 - by Maria Alice Miranda Bezerra Medeiros (11752002)

Fig 5 - by Kadio Jean-Jacques Olivier Kadio (15503159)

Fig 5 - by Mohammed Aliyu (10024123)

Fig 5 - by Mestewat Simeon (19233200)