Critical Membrane Concentration and Mass-Balance Model to Identify Baseline Cytotoxicity of Hydrophobic and Ionizable Organic Chemicals in Mammalian Cell Lines by Jungeun Lee (142511)

“…However, their applicability is limited to hydrophilic neutral compounds. To develop a prediction model that includes more hydrophobic and charged organic chemicals, a mass balance model was applied for mammalian cells (AREc32, AhR-CALUX, PPARγ-BLA, and SH-SY5Y) considering different bioassay conditions. …”

Comparison of variable distributions between the women in SAVOR-TIMI 53 trial based dataset v.s. the virtual patient dataset. by Yasunori Aoki (339027)

Comparison of variable distributions between the women in SAVOR-TIMI 53 trial based dataset v.s. the virtual patient dataset. by Yasunori Aoki (339027)

Effect of short-term storage of whole blood and PFP at RT on circulating miRNA-423-5p concentration. by Dinesh S. Chandel (8039750)

Advancing the science of NOWS research. by Sarah E. Maylott (14560785)

“…Approximately 50% of these newborns will develop Neonatal Opioid Withdrawal Syndrome (NOWS) within 5 days of birth. It is not known which infants will develop NOWS, therefore, the current hospital standard-of-care dictates a 96-hour observational hold. …”

Protocol measures. by Sarah E. Maylott (14560785)

“…Approximately 50% of these newborns will develop Neonatal Opioid Withdrawal Syndrome (NOWS) within 5 days of birth. It is not known which infants will develop NOWS, therefore, the current hospital standard-of-care dictates a 96-hour observational hold. …”

Cry variables. by Sarah E. Maylott (14560785)

“…Approximately 50% of these newborns will develop Neonatal Opioid Withdrawal Syndrome (NOWS) within 5 days of birth. It is not known which infants will develop NOWS, therefore, the current hospital standard-of-care dictates a 96-hour observational hold. …”

Image_2_MicroRNA-20a-5p Ameliorates Non-alcoholic Fatty Liver Disease via Inhibiting the Expression of CD36.tif by Xin Wang (91924)

“…Real-time PCR, dual-luciferase assay, and western blotting were employed to detect the relationship between miR-20a-5p and CD36. The expression level of miR-20a-5p was decreased in NAFLD patients, HFD mice, and free fatty acid (FFA)-treated HepG2 cells or primary mouse hepatocytes, accompanied by increased lipid production in hepatocytes. …”

Image_1_MicroRNA-20a-5p Ameliorates Non-alcoholic Fatty Liver Disease via Inhibiting the Expression of CD36.TIF by Xin Wang (91924)

“…Real-time PCR, dual-luciferase assay, and western blotting were employed to detect the relationship between miR-20a-5p and CD36. The expression level of miR-20a-5p was decreased in NAFLD patients, HFD mice, and free fatty acid (FFA)-treated HepG2 cells or primary mouse hepatocytes, accompanied by increased lipid production in hepatocytes. …”

Image_3_MicroRNA-20a-5p Ameliorates Non-alcoholic Fatty Liver Disease via Inhibiting the Expression of CD36.TIF by Xin Wang (91924)

“…Real-time PCR, dual-luciferase assay, and western blotting were employed to detect the relationship between miR-20a-5p and CD36. The expression level of miR-20a-5p was decreased in NAFLD patients, HFD mice, and free fatty acid (FFA)-treated HepG2 cells or primary mouse hepatocytes, accompanied by increased lipid production in hepatocytes. …”

Image1_Lidocaine Promoted Ferroptosis by Targeting miR-382-5p /SLC7A11 Axis in Ovarian and Breast Cancer.JPEG by Dan Sun (140898)

“…Furthermore, the treatment of lidocaine repressed tumor growth of ovarian cancer cells in vivo, in which the miR-382-5p expression was increased while SLC7A11 expression was decreased. …”

Image5_Dipyridamole activates adenosine A2B receptor and AMPK/cAMP signaling and promotes myogenic differentiation of myoblastic C2C12 cells.tif by Miguel Marco-Bonilla (16970271)

“…The expression of muscle differentiation proteins (Pax7, Mif5, MyoD, MyoG, and MHC), PKA/CREB, adenosine receptors (A1, A2A, A2B, and A3), ATP-channel pannexin-1 and the P2X7 receptor was analyzed via WB and RT-PCR. cAMP and AMPK activation was measured.…”

Effects of betaine on diuresis [μl/min/g k.w.], HR [bpm] and MABP [mmHg] in anesthetized Spontaneously Hypertensive rats and Wistar Kyoto normotensive rats. by Izabella Mogilnicka (13965422)

Table_5_The RNA N6-Methyladenosine Methyltransferase METTL3 Promotes the Progression of Kidney Cancer via N6-Methyladenosine-Dependent Translational Enhancement of ABCD1.XLSX by Yue Shi (128342)

Impact of 5′ nucleotidase disruption on <i>M</i>. <i>bovis</i> growth phenotype in axenic conditions. by Aga E. Gelgie (17661720)

Population dynamics modeling of split^50cM <i>ClvR</i> V1 introduced at a 50% release, with fitness cost per allele varying from 0–15%. by Georg Oberhofer (3401438)

Direct monetary reward in the PRT using a control population led to a reward induced bias. by Matthew Paul Wilkinson (11824625)

Image5_Overexpression of TaPIP1A enhances drought and salt stress tolerance in Arabidopsis: cross-species conservation and molecular dynamics.jpeg by Jie Han (128758)

S1 Data - by Michael C. Beall (18764654)

“…Germination occurred across a temperature range of 8–37°C and a pH range of 5–10 (≥83%), suggesting that neither pH nor temperature will limit germination in many environments. …”

DataSheet5_Yi-Shen-Hua-Shi granules inhibit diabetic nephropathy by ameliorating podocyte injury induced by macrophage-derived exosomes.ZIP by Mingzhu Liang (11011660)

“…Compared with the exosomes secreted by macrophages after an HG treatment, the exosome from macrophages treated with HG and YSHS granule showed lower inhibitory effects on podocyte activity, accompanied by the decreased upregulating effects of macrophage-derived exosomes on the miR-21a-5p in podocytes. miR-21a-5p mimics could reduce podocyte activity and promote caspase-3 shearing. …”