Image_8_In Vitro Characterization of 177Lu-DOTA-M5A Anti-Carcinoembryonic Antigen Humanized Antibody and HSP90 Inhibition for Potentiated Radioimmunotherapy of Colorectal Cancer.ti... by Tabassom Mohajershojai (9441050)

“…Moreover, the heat shock protein 90 inhibitor onalespib has previously demonstrated radiotherapy potentiation effects in vivo. In the present study, a ¹⁷⁷Lu-radiolabeled anti-CEA hT84.66-M5A mAb (M5A) conjugate was developed and the potential therapeutic effects of ¹⁷⁷Lu-DOTA-M5A and/or onalespib were investigated. …”

Image_6_In Vitro Characterization of 177Lu-DOTA-M5A Anti-Carcinoembryonic Antigen Humanized Antibody and HSP90 Inhibition for Potentiated Radioimmunotherapy of Colorectal Cancer.ti... by Tabassom Mohajershojai (9441050)

“…Moreover, the heat shock protein 90 inhibitor onalespib has previously demonstrated radiotherapy potentiation effects in vivo. In the present study, a ¹⁷⁷Lu-radiolabeled anti-CEA hT84.66-M5A mAb (M5A) conjugate was developed and the potential therapeutic effects of ¹⁷⁷Lu-DOTA-M5A and/or onalespib were investigated. …”

Image_9_In Vitro Characterization of 177Lu-DOTA-M5A Anti-Carcinoembryonic Antigen Humanized Antibody and HSP90 Inhibition for Potentiated Radioimmunotherapy of Colorectal Cancer.ti... by Tabassom Mohajershojai (9441050)

“…Moreover, the heat shock protein 90 inhibitor onalespib has previously demonstrated radiotherapy potentiation effects in vivo. In the present study, a ¹⁷⁷Lu-radiolabeled anti-CEA hT84.66-M5A mAb (M5A) conjugate was developed and the potential therapeutic effects of ¹⁷⁷Lu-DOTA-M5A and/or onalespib were investigated. …”

Image_7_In Vitro Characterization of 177Lu-DOTA-M5A Anti-Carcinoembryonic Antigen Humanized Antibody and HSP90 Inhibition for Potentiated Radioimmunotherapy of Colorectal Cancer.ti... by Tabassom Mohajershojai (9441050)

“…Moreover, the heat shock protein 90 inhibitor onalespib has previously demonstrated radiotherapy potentiation effects in vivo. In the present study, a ¹⁷⁷Lu-radiolabeled anti-CEA hT84.66-M5A mAb (M5A) conjugate was developed and the potential therapeutic effects of ¹⁷⁷Lu-DOTA-M5A and/or onalespib were investigated. …”

Image_2_In Vitro Characterization of 177Lu-DOTA-M5A Anti-Carcinoembryonic Antigen Humanized Antibody and HSP90 Inhibition for Potentiated Radioimmunotherapy of Colorectal Cancer.ti... by Tabassom Mohajershojai (9441050)

“…Moreover, the heat shock protein 90 inhibitor onalespib has previously demonstrated radiotherapy potentiation effects in vivo. In the present study, a ¹⁷⁷Lu-radiolabeled anti-CEA hT84.66-M5A mAb (M5A) conjugate was developed and the potential therapeutic effects of ¹⁷⁷Lu-DOTA-M5A and/or onalespib were investigated. …”

Potential miRNAs targeting PDE8A. by Thijs Booiman (185008)

“…#<p>Fold change in expression in which day 5 is compared to day 0; >1 is an increase and <1 is a decrease in expression.…”

Hematopoietic-restricted loss of Zeb1 decreases hematopoietic colony formation potential and ability to compete with wt HSPCs for contribution to all hematopoietic lineages. by Jueqiong Wang (11467505)

Overexpression of Hypo-Phosphorylated IκBβ at Ser313 Protects the Heart against Sepsis by Guang-Qing Wang (2936172)

“…Survival analysis showed that Tg mice exhibited decreased inflammatory cytokine levels and decreased rates of mortality in comparison to wild type (WT) mice, after sepsis in a cecal-ligation and puncture model (CLP). …”

High Serum Adiponectin Level Is a Risk Factor for Anemia in Japanese Men: A Prospective Observational Study of 1,029 Japanese Subjects by Kei Kohno (3383669)

“…Our study demonstrates, both clinically and epidemiologically, that a high serum adiponectin level decreases the amounts of erythroid-related variables and is a risk factor for anemia in Japanese men.…”

H₂O₂-induced mitochondrial size decrease is prevented by WY pre-treatment in hippocampal neurons. by Juan M. Zolezzi (586604)

The pro-inflammatory cytokines were mainly inhibited but anti-inflammatory genes were significantly activated in zebrafish embryos under PGRP5-KD conditions. by Xi Li (19208)

The mole fraction of arsenic acid (H₃As(V)O₄) species at pH 3.90 and pH 7.96, the minimum and maximum pH values observed in this study (Fig 8; Table 1) [23]. by Seth H. Frisbie (7821866)

The expression of Cregs is diminished in the allograft model with the progression of ATCMR. by Kazuaki Yamanaka (2541484)

“…Statistical significance was assessed by the t-test and Tukey’s HSD test. (A) qRT-PCR showed significantly diminished expression levels of Crry and CD59 mRNA in the allografts, compared to syngeneic grafts, at day 5 after transplantation. …”

Data_Sheet_1_Polydatin, A Glycoside of Resveratrol, Is Better Than Resveratrol in Alleviating Non-alcoholic Fatty Liver Disease in Mice Fed a High-Fructose Diet.docx by Guangshan Zhao (8828441)

Longer <i>L</i>_<i>u</i> significantly decreases and delays the peak of the sound-evoked CAPs of SGN fibers. by Maral Budak (6680351)

“…<p>(A) Sound-evoked CAPs of SGN fiber populations with varying unmyelinated segment length <i>L</i>_<i>u</i> at 70dB SPL, averaged over 50 simulations. Shaded regions correspond to the standard error of the mean and dashed lines correspond to the peaks of each CAP, labeled with the same colors as the CAPs. …”

Fluorescence detection of cellular toxicity as a function of starvation or treatment with the mTOR inhibitor, XL-765. by Kara R. Vogel (739629)

Early maladaptive schemas in adult survivors of interpersonal trauma: foundations for a cognitive theory of psychopathology by Thanos Karatzias (8376780)

Electron micrographs (magnification of × 30,000) and polyP levels (AU, arbitrary units) of <i>L</i>. <i>rhamnosus</i> CRL 1505. by María A. Correa Deza (4097602)

Comparison between fitted model (solid lines) and data (markers) at the whole lung scale (a) and in the same three example grids as Fig 2b. by Monica E. Shapiro (22622240)

Decreased α-cell mass and early structural alterations of the exocrine pancreas in patients with type 1 diabetes: An analysis based on the nPOD repository by Fidéline Bonnet-Serrano (4782546)

“…The β- and α-cell masses were calculated in the 66 patients and the 50 controls for which the pancreas weight was available. …”