Calcineurin and calpain were abnormal in PAN-treated podocytes. by Fangrui Ding (659863)

“…Compared to untreated control podocytes, calcineurin activity was up-regulated in podocytes treated with various concentrations of PAN (25, 50, 75, 100, or 125 μg/ml) after 24 h. (B, C) Interestingly, the protein expression of full-length 60-kDa calcineurin was decreased in a dose-dependent manner in PAN-treated podocytes; this effect was the opposite of that observed on calcineurin activity. …”

Supplementary Material for: Comparison of urinary protein/creatinine ratio as an alternative to 24-hour proteinuria in Lupus Nephritis: TUNARI study by Gutiérrez-Peredo G.B. (16439571)

“…Results: We compared 112 samples of 75 patients with LN, with a mean age of 34.5 ± 11.8 years. …”

Organ level model. by Shayoni Ray (179927)

“…<p>An organ-level simulation containing three ideally localized clefts is shown at (a) 0 MCS and (b) 1500 MCS (Scale = 50 µm). The results were quantified with (c) cleft depth and (d) spanning angle. …”

Cytotoxicity of candidate agents to cholangiocarcinoma cells. by Chiara Braconi (235041)

“…All three compounds decreased cell viability in a concentration-dependent manner, with an IC50 for felodipine of 26±5 µM, nitrendipine, 44±10 µM and nifedipine, 15±4 µM. …”

Data_Sheet_1_The Role of Sustained Photoprotective Non-photochemical Quenching in Low Temperature and High Light Acclimation in the Bloom-Forming Arctic Diatom Thalassiosira gravid... by Thomas Lacour (5877947)

“…T. gravida growth remained possible under a wide range of irradiances but photosynthetic plasticity was higher at moderately low light (up to ~50 μmol photons m⁻² s⁻¹), nevertheless corresponding to the mean in situ conditions under which it predominates, i.e., underneath the spring thin-ice punctuated with melting ponds. …”

Image_1_Longitudinal real world correlation study of blood pressure and novel features of cerebral magnetic resonance angiography by artificial intelligence analysis on elderly cog... by Shasha Sun (775101)

“…</p>Results<p>After matching with age and gender, 208 CI patients and 208 control subjects were finalized the follow-up (3.46 ± 3.19 years) with mean age at 84.47 ± 6.50 years old. Pulse pressure (PP) in first tertile (<58 mmHg) (OR 0.588, 95% confidence interval (CI): 0.362–0.955) was associated with a decreased risk for CI, and ≥50% stenosis of the left PCA (OR 2.854, 95% CI: 1.387–5.872) was associated with an increased risk for CI after adjusting for body mass index, myocardial infarction, and stroke history. …”

Table_1_Longitudinal real world correlation study of blood pressure and novel features of cerebral magnetic resonance angiography by artificial intelligence analysis on elderly cog... by Shasha Sun (775101)

“…</p>Results<p>After matching with age and gender, 208 CI patients and 208 control subjects were finalized the follow-up (3.46 ± 3.19 years) with mean age at 84.47 ± 6.50 years old. Pulse pressure (PP) in first tertile (<58 mmHg) (OR 0.588, 95% confidence interval (CI): 0.362–0.955) was associated with a decreased risk for CI, and ≥50% stenosis of the left PCA (OR 2.854, 95% CI: 1.387–5.872) was associated with an increased risk for CI after adjusting for body mass index, myocardial infarction, and stroke history. …”

Data_Sheet_1_The role of immune suppression in COVID-19 hospitalization: clinical and epidemiological trends over three years of SARS-CoV-2 epidemic.PDF by Marta Canuti (336637)

“…The proportion of immune suppressed patients among all hospitalizations (initially stable at <20%) started to increase around December 2021, and remained high (30–50%). This change coincided with an increase in the proportions of older patients and patients with co-morbidities and with a decrease in the proportion of patients with severe outcomes. …”

Cerebellar cortex of SCA3 patients. by Tzu-Yun Wang (427574)

Cerebral cortex of SCA3 patients. by Tzu-Yun Wang (427574)

DataSheet1_The effect of transcutaneous electrical stimulation of the submental area on the cardiorespiratory response in normal and awake subjects.docx by Abdulaziz Alsharifi (14786368)

“…A three-way ANOVA indicated that BP decreased significantly with TES (systolic: p = 4.93E-06, diastolic: p = 3.48E-09, mean: p = 3.88E-08). …”

Neuronal cells expressing the cGMP gated cation channel TAX-2/TAX-4 are required to modulate the effect of neuronal stress on fat-remodeling in the intestine. by Laetitia Chauve (8600553)

“…Because <i>tax-4</i> RNAi only has a moderate effect, we tested the effect of genetic mutants. …”

Data_Sheet_1_Effects of Different Grazing Disturbances on the Plant Diversity and Ecological Functions of Alpine Grassland Ecosystem on the Qinghai-Tibetan Plateau.docx by Wenlong Li (571749)

“…Aboveground biomass (AGB) and belowground biomass (BGB) decreased, respectively, by 41.91% (95% CI: −50.91 to −32.88%) and 17.68% (95% CI: −26.94 to −8.52%). …”

Data Sheet 1_Blue light modulates the interactive effects of far-red light and day–night temperature difference on the growth, morphology and physiology of arugula and lettuce.docx... by Awais Ali (8613051)

“…Morphological acclimation, such as thinner leaves under FR light and +DIF, led to a decrease in single-leaf daily carbon gain, whereas high blue light improved daily carbon gain by enhancing leaf thickness and pigment levels. …”

3HA Nanoparticle Stability Data by Timothy Chang (4727196)

“…<p>Vaccine distribution infrastructure remains inadequate in many parts of the world, and it is estimated that up to 40-50% of all vaccine doses are wasted in certain countries. …”

Neurons are uncorrelated during PABA and exhibit Poisson-like irregularity. by Nigel Stepp (683934)

“…<p>A) Neuronal firing is weakly correlated during ongoing activity in awake monkeys that display neuronal avalanches in the local field potential (LFP) Distributions of pair-wise correlation coefficients of firing in the pre-motor cortex of two awake monkeys, S1 (1.2 Hz mean rate) and S2 (5.2 Hz mean rate). …”

GUCY2C modulates systemic genotoxicity and tumorigenesis. by Jieru Egeria Lin (181534)

Oxidative stress in INS1E and alphaTC1 cells in 3D aggregates. by Mireille M. J. P. E. Sthijns (12245491)

“…B) Seeding INS1E and alphaTC1 cells in the ratios 100:0 and 50:50 in 3D aggregates exposed to 500 μM H₂O₂ decreased the percentage of oxidative stress–positive INS1E cells. …”

Firing properties of DG granule cells evoked by current injections. by Hamid Gholami Pourbadie (692631)

“…<p>A, Aβ pathogenesis in the EC produced changes in firing pattern and decreased firing rate of DG granule cells at different current injections. …”

Cell viability and recovery. by Eva Capdevila-Busquets (683895)

“…Based on empty vector (MYC-tag) as a negative control, we do not observe a significant recovery of apoptosis-induced cells after gene overexpression. …”