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ns decrease » _ decrease (Expand Search), use decreased (Expand Search), ash decreased (Expand Search)
nn decrease » _ decrease (Expand Search), mean decrease (Expand Search), gy decreased (Expand Search)
we decrease » _ decrease (Expand Search), mean decrease (Expand Search), teer decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
ns decrease » _ decrease (Expand Search), use decreased (Expand Search), ash decreased (Expand Search)
nn decrease » _ decrease (Expand Search), mean decrease (Expand Search), gy decreased (Expand Search)
we decrease » _ decrease (Expand Search), mean decrease (Expand Search), teer decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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Discovery of New Inhibitors of Hepatitis C Virus NS3/4A Protease and Its D168A Mutant
Published 2019“…Hepatitis C virus (HCV) is a human pathogen with high morbidity. The HCV NS3/4A protease is essential for viral replication and is one of the top three drug targets. …”
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VCP inhibition induces accumulation of ubiquitinated-proteins and decreases NFκB-expression.
Published 2016“…The increase in ubiquitinated-protein accumulation in soluble protein-fraction suggests that the DDN<sup>DBeQ</sup> treatment alters VCP-function resulting in proteostasis-inhibition and ER-accumulation of these proteins. We also see a significant decrease in expression of tumor-mediator, NFκB in DDN/DDN<sup>DBeQ</sup> treated samples as compared to the control-vehicle, although DDN<sup>DBeQ</sup> was most effective as anticipated. …”
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Inhibition of Fatty Acid Synthase Decreases Expression of Stemness Markers in Glioma Stem Cells
Published 2016“…In this study, we examined the expression and role of fatty acid synthase (FASN), a key lipogenic enzyme, in GSCs. …”
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