Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades by Ihab Shawish (13015516)

Subjects:

Passive transfer of humanized anti-NS1 mAb 33D2 into DENV-inoculated mice decreases viral titer and NS1 level in mouse sera. by Sen-Mao Tien (12481273)

Inhibition of PKCδ causes a decrease in viral replication. by Brian D. Carey (6092747)

The fraction of predicted heterozygotes that are set to “No Call” by RHA decreases as the size of the heterozygote cluster increases. by Orna Mizrahi-Man (42539)

The motor torque curves of load increase/decrease (A) the load of 10 N • m (B) the load of 20 N • m. by Taochang Li (20642935)

“…<p>The motor torque curves of load increase/decrease (A) the load of 10 N • m (B) the load of 20 N • m.…”

The motor speed curves of load increase/decrease (A) the load of 10 N • m (B) the load of 20 N • m. by Taochang Li (20642935)

“…<p>The motor speed curves of load increase/decrease (A) the load of 10 N • m (B) the load of 20 N • m.…”

Genes whose expression was decreased by 1 mM ouabain by more than 2-fold. by Larisa V. Smolyaninova (3600053)

Colon tissue and organoid AJC protein expression is decreased with LD shifting in Per2::Luc mice. by Laura Tran (10924702)

Stimulation with PMA in Jurkat cells led to a decrease in promoter activity. by Maike Stegen (8578665)

Decreased biofilm formation in the Δ<i>tad123</i> mutant cells. by Tra-My Duong-Nu (7300970)

Knockout of RPL13a paralogs decreases 60S, 80S and polysomes. by Francisca S. Borges (18570277)

Fluorescence ratio imaging of mouse blastocysts based on 340 nm and 380 nm excitation, with bright-field images. by Ayaka Fujishima (21221913)

Nicotine decreased Akt phosphorylation in SK-BR-3 cells. by Masanori A. Murayama (5774585)

Treatment with low doses of GI254023X causes a mild decrease in ADAM10 surface expression that correlates with a marked impairment of HCV infectivity. by Belén Carriquí-Madroñal (17396512)

TUDCA decreases ER stress in HOX neonatal rat lungs. by Kirkwood A. Pritchard Jr. (13449794)

“…<p>(<b>A</b>) The expression levels of ER stress markers (P-PERK 0.6±0.1-fold, p<0.001, n = 5; PERK 0.7±0.1-fold, p = 0.00364, n = 5; P-IRE1α 0.6±0.0-fold, p<0.001, n = 5; IRE1α 0.6±0.1-fold, p<0.001, n = 5; GRP78 0.8±0.1-fold, p<0.001, n = 5; cleaved ATF6 0.1±0.0-fold, p<0.001, n = 5; spliced XBP1 0.3±0.0-fold, p<0.001, n = 5; 2 males and 3 females) are all decreased while the N-glycosylated VEGFR2 is increased (3.5±0.2-fold, p<0.001, n = 5) in HOX neonatal lungs at P10 indicating TUDCA can attenuate hyperoxia-induced ER stress. …”

Tax expression is associated with decreased cellular motility. by Saumya Ramanayake (7879091)

ROS and superoxide decrease in the dormant form of mycobacteria. by Amar Yeware (7115063)

Oxytocin decreases locally evoked CeA GABAergic signaling and blunts alcohol effects. by Brendan J. Tunstall (6593357)

Discovery of Triazolyl Derivatives of Cucurbitacin B Targeting IGF2BP1 against Non-Small Cell Lung Cancer by Fan-Fan Shang (16953264)

“…Among them, derivative <b>A11</b> had the most potent antiproliferative activity against A549 lung cancer cells (IC₅₀ = 0.009 μM) and was approximately 10-fold more potent than CuB, while the cytotoxicity of <b>A11</b> toward normal L02 cells was about 10-fold less potent, indicating a much wider therapeutic window than CuB. …”

Results isoprenaline (30nM) experiment. by L. Cao (3526226)