Decreases in white matter integrity in t(1;11) translocation carriers (n = 7) versus non-carriers (n = 13) and in patients (n = 34) versus controls (n = 33). by Heather C. Whalley (287657)

“…To aid visualization the results (pfwe < 0.05) are thickened using the “tbss-fill” command. Statistics for FA decreases in the patient group versus controls for these peaks; cluster 1: p = 0.023 at [-3, 28, 6; left genu of corpus callosum], cluster 2: p = 0.032 at [29, 26, 15; right fronto-occipital fasciculus], cluster 3: p = 0.012 at [11, 26, 14; right genu of corpus callosum], cluster 4: p = 0.033 at [20, 25, 0; right acoustic radiation], and cluster 5: p = 0.031 at [28, -24, -8; right fornix] i.e. for clusters 1–5 respectively, see, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0130900#pone.0130900.t002" target="_blank">Table 2</a>).…”

The location of landmark for facial orientation. by Motonori Kurosumi (11237990)

Primer sequences used to produce RNA IRES Mutants (M1-M6) by the Site-directed mutagenesis method. by Jawhar Gharbi (11492361)

Relative abundance. by Tejaswini Baral (14320736)

Performance of the intact model. by Yaroslav I. Molkov (542831)

“…At lower values of <i>α</i> two distinct regimes exist: the first has a phase difference between flexor centers less than 0.5 (lower branch) which corresponds to the activation pattern shown in <b>A</b> (LF leads, RF activates on LF’s shutdown, then a pause until LF activates again) and the second regime has a phase difference greater than 0.5 (upper branch) when RF activates first and LF activates on RF’s shutdown (not shown on <b>A</b>). …”

Protein arginine methyltransferase 5 (PRMT5) promotes survival of lymphoma cells via activation of WNT/B-catenin and AKT/GSK3B proliferative signaling by Chung, Jihyun

“…We show that PRMT5 stimulates WNT/B-CATENIN signaling through direct epigenetic silencing of pathway antagonists, AXIN2 and WIF1, and indirect activation of AKT/GSK3 signaling.PRMT5 inhibition with either shRNA-mediated knockdown or a specific small molecule PRMT5 inhibitor, CMP-5, not only leads to derepression of WNT antagonists and decreased levels of active phospho-AKT (Thr-450 and Ser-473) and inactive phospho- GSK3B (Ser-9) but also results in decreased transcription of WNT/B-CATENIN target genes, CYCLIN D1, c-MYC, and SURVIVIN, and enhanced lymphoma cell death. …”
Get full text
Get full text

Heatmap of topmost bacteria genera. by Tejaswini Baral (14320736)

Face angle used as stimuli. by Motonori Kurosumi (11237990)

Effects of the facial orientation on age impression. by Motonori Kurosumi (11237990)

Influence of chemical components of PVAC during storage of RBC. by Felix Sellberg (8098511)

“…In <b>(b)</b> values after 1 month (end of storage) are shown: PVA at 100 μg/mL increased hemolysis while PVAC at 2.5 mg/mL, 500 and, 100 μg/mL decreased the levels of hemolysis compared to the control.…”

Discovery of Novel Pyrimidine-Based Capsid Assembly Modulators as Potent Anti-HBV Agents by WooChan Kim (10690503)

“…Moreover, treatment with compound <b>23h</b> for 5 weeks significantly decreased serum levels of HBV DNA levels (3.35 log reduction) in a human liver-chimeric uPA/SCID mouse model, and these effects were significantly increased when <b>23h</b> was combined with tenofovir, a nucleotide analogue inhibitor of reverse transcriptase used for the treatment of HBV infection.…”

The frequency (<i>FD</i>) and the level (<i>LD_av</i>) of the <i>CHL1</i> mRNA decrease in renal cancer (CC-RCC). by Vera N. Senchenko (53211)

Representative examples of iNOS (1^st row), RANK (2^nd row) and TRAP (3^rd row) immunostainning in experimental periodontitis in rats. by Conceição S. Martins (468492)

Hepatic IRE1α/XBP1 pathway of the UPR is decreased in pediatric cholestatic liver disease (pCLD) samples compared to pediatric normal (pNormal) livers. by Alyssa Kriegermeier (4707226)

“…<p>A) Hepatic gene expression of IRE1α, XBP1s and downstream targets EDEM1 and ERdj4 were measured via qPCR. pCLD livers (n = 10) had decreases in IRE1α, XBP1, EDEM1 and ERdj4 expression compared to pNormal livers (n = 9). …”

Catalytic activity of PP2A following its demethylation by L-homocysteine and adenosine treatment. by Tejasvi Dudiki (827360)

“…Demethylation of sperm PP2A by L-homocysteine and adenosine results in decreased total phosphatase and PP2A catalytic activity. …”

Histamine 1 Receptor Blockade Enhances Eosinophil-Mediated Clearance of Adult Filarial Worms by Ellen Mueller Fox (774436)

“…Although fexofenadine-treated mice had decreased antigen-specific IgE levels as well as lower splenocyte IL-5 and IFNγ production, they exhibited a greater than fourfold rise in eosinophil numbers at the tissue site where adult <i>L</i>. …”

Immune modulation by histamine during <i>L</i>. <i>sigmondontis</i> infection. by Ellen Mueller Fox (774436)

Image_1_Loss of the Essential Autophagy Regulators FIP200 or Atg5 Leads to Distinct Effects on Focal Adhesion Composition and Organization.TIF by Emelia A. Assar (9201743)

“…We provide evidence suggesting the primary autophagy regulators Atg5 and FIP200 both play a role in cell motility and extracellular matrix adhesion. …”

Image_2_Loss of the Essential Autophagy Regulators FIP200 or Atg5 Leads to Distinct Effects on Focal Adhesion Composition and Organization.TIF by Emelia A. Assar (9201743)

“…We provide evidence suggesting the primary autophagy regulators Atg5 and FIP200 both play a role in cell motility and extracellular matrix adhesion. …”

The initiation region/matrix attachment region (IR/MAR) increased the homogeneously staining region (HSR) elongation rate and decreased the frequency of micronuclei after elevation... by Shun-suke Tanaka (604228)