Silencing TRPM7 in Mouse Cortical Astrocytes Impairs Cell Proliferation and Migration via ERK and JNK Signaling Pathways by Zhao Zeng (478844)

“…Knocking down TRPM7 with specific siRNA impairs the proliferation and migration of astrocytes by 40.2% ± 3.9% and 40.1% ± 11.5%, respectively. Consistently, inhibition of TRPM7 with 2-aminoethoxydiphenyl borate (2-APB) also decreases astrocyte proliferation and migration by 46.1% ± 2.5% and 64.2% ± 2.4%. …”

Exemplar display during target selection. by Joshua B. Moskowitz (8506380)

Stability study results of a) & b) are ACE and CAP at 40°C±2°C/75%RH±5%RH, c) & d) are ACE and CAP at 25°C±2°C/60%RH±5%RH, e) & f) are ACE and CAP at 2–8°C. by Jaganmohan Somagoni (532859)

Structural mapping of collective dynamics profiles for the CDK5-p25, CDK6/V-cyclin and CDK9-cyclin T complexes. by Gabrielle Stetz (831541)

“…<p>Structural mapping of the GNM-based collective dynamics profiles driven by the slowest three modes is shown for the CDK5-p25 complex (pdb id 3O0G) (A), CDK6-Vcyclin complex (pdb id 2EUF) (B) and CDK9-cyclin T complex (pdb id 4EC8) (C). …”

Boxplot of children’s rated emotion valence during the baseline phase, and on the first and second test trial of Study 1. by Stella C. Gerdemann (12436680)

Table_5_Unraveling the genetic evolution of SARS-CoV-2 Recombinants using mutational dynamics across the different lineages.XLSX by Varsha Ravi (12267659)

“…The spontaneously/dynamically increasing and decreasing trends of mutations highlight the loss of mutations in the Recombinants that were associated with the SARS-CoV-2 replication efficiency, infectivity, and disease severity, rendering them functionally with low infectivity and pathogenicity. …”

<i>nt5e</i> confers Nt5e activity on <i>S. sanguinis</i> SK36 whole cells. by Jingyuan Fan (159998)

“…<p>Nt5e activity was measured by the release of inorganic phosphate (Pi) from adenine nucleotides. …”

Organelle recombination genes and body plans across taxa. by David M. Edwards (10692265)

Flowchart for the SI model of <i>T</i>. <i>cruzi</i> transmission in a community of competent and non-competent hosts. by Alheli Flores-Ferrer (2151817)

A high vaccine uptake (> 90% or higher among the eligible population) is crucial to prevent a wave when lifting restrictions after completing vaccination campaigns. by Simon Bauer (11378195)

Table 5_Therapeutic potential of five frequently prescribed herbs in obesity-associated Hashimoto’s thyroiditis: insights from efferocytosis regulation.xlsx by Jiahao Zhou (11385383)

“…Moreover, TCM offers significant benefits in regulating lipid metabolism and decreasing systemic inflammation.</p>Methods<p>Targets of five high-frequency herbs (Hedysarum multijugum Maxim, Radix Bupleuri, Prunella vulgaris, Fritillaria thunbergii Bulbus, and Angelicae sinensis Radix) were obtained from the TCMSP and Swiss Target Prediction databases. …”

Percent decrease of the marker pigment concentrations (mean ± standard deviation of triplicate microcosms, and the probability) treated with 1.6 mg L⁻¹ H₂O<su... by Varunpreet Randhawa (302690)

Inhibition of Neuroblastoma Tumor Growth by Ketogenic Diet and/or Calorie Restriction in a CD1-Nu Mouse Model by Raphael Johannes Morscher (751235)

“…Neuroblastoma growth reduction correlated with decreased blood glucose concentrations and was characterized by a significant decrease in Ki-67 and phospho-histone H3 levels in the diet groups with low tumor growth. …”

Effect of H₂O₂ on cell membrane rupture in hypo-osmotic conditions. by Alexis Mougeolle (709121)

Changes after 45 minutes in the proportion of LTP, LTD or no plasticity responses observed in L5PyNs population induced by the HFS protocol in the presence of D1R agonist or antago... by Claire Nicole Jeanne Meunier (703124)

“…<p>(A and D) Percentages of L5PyNs displaying LTP, LTD or no plasticity in 129/Sv mice and 5-HT_1AR-KO mice in control conditions. …”

Table_5_Integrative Analysis of LGR5/6 Gene Variants, Gut Microbiota Composition and Osteoporosis Risk in Elderly Population.DOCX by Dong-sheng Di (11634688)

“…The rs10920362 CT/TT genotype associated with a decreased relative abundance of Actinobacteria (β = −1.32, P < 0.001), Bifidobacteriaceae (β = −1.70, P < 0.001), and Bifidobacterium (β = −1.70, P < 0.001) compared to the CC genotype.…”

BrdU assay in control siRNA (blue bars) and in PAX6 knockdown (red bars) limbal epithelial cells (LECs) without and after 1µM or 5µM RA incubation for 48 hours. by Shao-Lun Hsu (6856259)

“…Significant p values (<0.05) are highlighted. BrdU assay shows a significantly lower proliferation rate in the PAX6 siRNA knockdown group than in control siRNA group (p < 0.001). 5µM RA treatment significantly decreased proliferation rate in controls (p = 0.025). …”

Generation and Tg^cog protein expression profile of the <i>ColIITg^cog</i> mouse. by Louise H. W. Kung (693522)

Anomalous Non-Prussian Blue Structures and Magnetic Ordering of K₂Mn^II[Mn^II(CN)₆] and Rb₂Mn^II[Mn^II(CN)<... by Jae-Hyuk Her (1769134)

“…The magnetic ordering temperature, <i>T</i>_c, increases as K⁺ (41 K) > Rb⁺ (34.6 K) > Cs⁺ (21 K) for A₂Mn[Mn(CN)₆] in accord with the increasing deviation for linearity of the Mn−N−C linkages [148.8 (K⁺) > 153.3 (Rb⁺) > 180° (Cs⁺)], decreasing Mn(II)···Mn(II) separations [5.09 (K⁺) < 5.19 (Rb⁺) < 5.30 Å (Cs⁺)], and decreasing size of the cation (increasing electrostatic interactions). …”

Confirmation of miRNA level by RT-qPCR. by Qin-Min Ge (3838885)

“…<p>Relative expression of each miRNA was normalized to hsa-miR-423-5p level. miR-142-5p, miR-22-3p, miR-191-5p, miR-23a-3p and miR-4456 were significantly decreased in both the sepsis-induced AKI and sepsis-non AKI groups compared with the healthy controls. miR-4270, miR-4321 and miR-3165 were obviously increased in the sepsis-induced AKI, and miR-3165 also was obviously increased in sepsis-non AKI group compared with the healthy controls. …”