Generation of CYP5122A1 half knock-outs. by Smriti Verma (204089)

“…<b>G:</b> Bar graph representing mean fluorescence intensities of CYP5122A1 fluorescence in WT versus HKO parasites (mean± SE, n = 3), * P≤0.05.…”

Ovariectomy (OVX) induced decline in brain glucose uptake and BBB GLUT1_{55 Kda} expression: prevention by 17β-estradiol. by Fan Ding (302565)

“…Quantitative analysis of brain glucose uptake demonstrated a significant decrease in OVX condition (**, p<0.01, bars represent mean value±SEM, n = 5–7), which was partially prevented by E2 treatment (50 µg/kg, SC) (*, p<0.05; bars represent mean value±SEM, n = 5–6). …”

Exome sensitivity with varying exome site density. by Zhong Zhuang (303261)

Short-term time-restricted feeding during the resting phase is sufficient to induce leptin resistance that contributes to development of obesity and metabolic disorders in mice by Katsutaka Oishi (278169)

Effect of the cinnamaldehyde analogs (100 µM) on different QS-regulated phenotypes. by Gilles Brackman (147645)

“…</p>**<p>; compound was used in 50 µM concentration.</p>***<p>; for <i>V. cholerae</i> NCTC 8457 results are expressed as the percentage increase (instead of decrease) in biofilm biomass compared to the untreated control.…”

The expression of pain receptors in <i>α</i>-GalA KO males frontal paws. by Jarmila Lakomá (152379)

“…<p>A) Immunohistochemistry of 12 µm frozen coronal sections of α-GalA KO males (n = 3) showed different expression at the protein level of the specific pain (Nav1.8), heat (TRPV1) and cold (TRPM8, Immunological Science) receptors in comparison to their WT controls (n = 3). B) The western blot analysis of Nav1.8 expression (∼220 kDa) in the whole protein extract from skin of frontal paws confirmed 1.5 fold increased protein expression of Nav1.8 in case of α-GalA KO males (n = 5) when compared to WT males (n = 5), p = 0.0246. …”

DataSheet1_Global water distribution in the mantle transition zone from a seismic isotropic velocity model and mineral physics modeling.docx by Zongfa Wang (13276743)

“…The upper MTZ (410–520 km) and the lower MTZ (520–660 km) contain 0.3–0.5 wt% and 0.15–0.2 wt% water, respectively, implying water contents of the MTZ decrease with increasing depths. …”

Optogenetic manipulation of slow oscillations. by Ksenia V. Kastanenka (3692380)

“…APP: VSD trace depicting restoration of slow oscillations in APP mice expressing ChR2 virus under CamKIIα promoter when stimulated with light at 0.6 Hz. A decrease in power is evident after light stimulation is stopped. …”

Short telomeres worsen diabetes severity in Akita mice and cause β-cell loss. by Nini Guo (227926)

“…<b>B</b>. Ins2^C96Y/WTmTR^−/−iG₄ mice have decreased β-cell mass compared with Ins2^C96Y/WT mice. …”

Tumor-specific expression of the α2β1 integrin caused rapid tumor formation and increased tumor growth in vivo, independent of host microenvironment. by Thuy Tran (182420)

“…<p><i>A</i>, Orthotopic injections of SCC lines HPV/KO-1 and -2 into either non-K14-HPV16 transgenic, WT or α2-null (KO) hosts resulted in increased tumor latency by approximately 5–10 days, as compared to SCC lines HPV/WT-1 and -2 (p = 0.0003). …”

A Novel Missense Mutation, I890T, in the Pore Region of Cardiac Sodium Channel Causes Brugada Syndrome by Anna Tarradas (105463)

“…Sodium currents were studied using standard whole cell patch-clamp protocols and immunodetection experiments were performed using an antibody against human Na_v1.5 channel. A marked decrease in current density was observed in cells expressing the I890T channel (from −52.0±6.5 pA/pF, <em>n</em> = 15 to −35.9±3.4 pA/pF, <em>n</em> = 22, at −20 mV, WT and I890T, respectively). …”

Synthesis and characterization of stir casted Cu-ZrO2-Graphite hybrid metal matrix composites for thermal management structures by Mittal, Prateek

“…ZrO2 and Graphite reinforcements were added (0.5–0.5, 1.0–1.0, 1.5–1.5 and 2.0–2.0 wt %) in the four composite samples prepared via stir casting. …”
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Ascorbic acid enhances demethylation of H3K27me3 and induces <i>Prdm14</i>, <i>Tsix</i>, and <i>Xist</i>. by Yasunao F. Kamikawa (741742)

“…(E) The H3K27me3 levels are decreased while the 5hmC levels are elevated following AA exposure. …”

VPS34 inhibition depletes intracellular iron by blocking iron uptake through enhanced degradation of TFR and excess iron rescues the growth defect in RKO cells. by Marek J. Kobylarz (9292599)

“…Data is derived from three independent experiments and presented as mean ± SD, ***, p < 0.001; NS, not significant (two-way ANOVA). …”

Figure 4 from FLT3/CD99 Bispecific Antibody–Based Nanoparticles for Acute Myeloid Leukemia by Atham Ali (19345980)

Lignocellulosic Residues from the Brazilian Juice Processing Industry as Novel Sustainable Sources for Bioenergy Production: Preliminary Assessment Using Physicochemical Characteri... by José L. F. Alves (10436273)

“…Proximate composition revealed moisture, volatile matter, fixed carbon and ash contents in the range of 7.8-9.3%, 67.1-74.2%, 16.2-22.0% and 1.6-5.7%, respectively. Typical values for carbon (44.8-49.9 wt.%), hydrogen (5.5-6.6 wt.%) and oxygen (40.1-44.2 wt.%), with low sulfur (< 0.1 wt.%) and nitrogen (< 2.7 wt.%) contents were found. …”

Visual sensitivity loss and electrophysiological changes during ON in MOG^TCRxThy1CFP mice. by Katie Lidster (479714)

“…(B) Typical waveform VEP showing P1 (first positive peak), N1 (first negative peak), P2 (second positive peak). (C) Decrease in mean VEP amplitude after immunisation of MOG^TCRxThy1CFP mice to develop ON (n=5). …”

<i>Kif3a</i> controls renal branching morphogenesis in a GLI3R-dependent manner. by Lijun Chi (196000)

“…<p>(A–C’’) Cytokeratin immunofluorescence demonstrating ureteric branching at E11.5 and E12.5. The branch pattern is similar among <i>WT</i> (A,B), <i>Kif3a^−/−UB</i> (A’,B’) and <i>Kif3a^−/−UB</i>;<i>Kif3a^Δ699/+</i>(constitutive expression of <i>Gli3^Δ699/+</i> in <i>Kif3a^−/−UB</i> background, A’’, B’’) kidneys. …”

The outgrowth and branching of neurites and axons are impaired in hippocampal neurons from βPix neuronal isoform KO (βPix-NIKO) mice. by Younghee Kwon (1823413)

“…The βPix-NIKO neurons show a 19% decrease in the longest neurite length, a 21% decrease in total neurite length, and a 31% decrease in average axon length compared with the WT neurons. …”

SNX-1, IWN3* and RME-8 expression levels control RME-8 microdomain localization and positioning. by Anne Norris (268484)

“…Each data point is an individual worm, error bars indicate Mean with 95% CI, student t-test statistical analysis done on ratiometric data, and ANOVA on Pearson’s correlation data, with p < .5 = *, p < .01 = **, p < .001 = ***. …”