Data_Sheet_3_Tfam Knockdown Results in Reduction of mtDNA Copy Number, OXPHOS Deficiency and Abnormalities in Zebrafish Embryos.PDF by Auke B. C. Otten (8965244)

“…Morphant embryos displayed abnormal development of the eye, brain, heart, and muscle, as well as a 50 ± 22% decrease in ATP production. Transcriptome analysis revealed a decrease in protein-encoding transcripts from the heavy strand of the mtDNA, and down-regulation of genes involved in haem production and the metabolism of metabolites, which appear to trigger increased rRNA and tRNA synthesis in the nucleoli. …”

Supplementary Material for: Selective Serotonin Reuptake Inhibitors and Serotonin Noradrenaline Reuptake Inhibitors withdrawal changes DSM presentation of mental disorders: Results... by Cosci F. (4134769)

“…Using a new nosographic classification of withdrawal syndromes due to SSRI/SNRI decrease or discontinuation (by Chouinard and colleagues), we explored whether DSM is adequate to identify DSM disorders when withdrawal occurs. …”

Data_Sheet_2_Tfam Knockdown Results in Reduction of mtDNA Copy Number, OXPHOS Deficiency and Abnormalities in Zebrafish Embryos.pdf by Auke B. C. Otten (8965244)

“…Morphant embryos displayed abnormal development of the eye, brain, heart, and muscle, as well as a 50 ± 22% decrease in ATP production. Transcriptome analysis revealed a decrease in protein-encoding transcripts from the heavy strand of the mtDNA, and down-regulation of genes involved in haem production and the metabolism of metabolites, which appear to trigger increased rRNA and tRNA synthesis in the nucleoli. …”

Data_Sheet_4_Tfam Knockdown Results in Reduction of mtDNA Copy Number, OXPHOS Deficiency and Abnormalities in Zebrafish Embryos.PDF by Auke B. C. Otten (8965244)

“…Morphant embryos displayed abnormal development of the eye, brain, heart, and muscle, as well as a 50 ± 22% decrease in ATP production. Transcriptome analysis revealed a decrease in protein-encoding transcripts from the heavy strand of the mtDNA, and down-regulation of genes involved in haem production and the metabolism of metabolites, which appear to trigger increased rRNA and tRNA synthesis in the nucleoli. …”

Dataset for: Vascular narrowing in pulmonary arterial hypertension is heterogeneous: rethinking resistance by Nina Rol (3929081)

“…Within each order the decrease in diameter of affected vessels is variable with an averaged diameter fraction of 50-70%. …”

Trilemma of life cycle carbon, employment, and costs of trucking industry's shift toward automation and electrification by Mandouri, Jafar

“…Autonomy and electrification combined could lead to a 50% decrease in emissions and 46% savings in life cycle costs. …”
Get full text
Get full text

MK-2206 induced cytotoxicity, inhibited proliferation and was able to overcome the protective effects of the tumor microenvironment. by Vijay Ramakrishnan (117159)

“…<p>When we cultured MM cell lines with indicated concentrations of MK-2206 for 48 hrs we observed dose dependent decrease in <b>A)</b> viability as observed by MTT assays and <b>B)</b> tritiated thymidine uptake indicative of inhibition of proliferation albeit with differences in the sensitivity of cell lines to MK-2206. …”

Macromolecular biosynthetic parameters and metabolic profile in different life stages of <i>Leishmania braziliensis</i>: Amastigotes as a functionally less active stage by Marlene Jara (774474)

image_1.jpeg by Monique Mendelson (4873582)

“…There was a significant decrease in apnea–hypopnea-index following exercise training (mean decrease of 8.9 events/h; 95% CI: −13.4 to −4.3; p < 0.01), which was accompanied by a reduction in subjective sleepiness, an increase in VO2peak and no change in BMI. …”

Image_1_High Potassium Application Rate Increased Grain Yield of Shading-Stressed Winter Wheat by Improving Photosynthesis and Photosynthate Translocation.tif by Yi Wang (32470)

“…<p>Wheat (Triticum aestivum L) production on the Huang-Huai Plain of China has substantially affected in the past 50 years as a result of the decreasing total solar radiation and sunshine hours. …”

Influence of treatment on occludin. by An-Chih Chen (3934331)

“…^# indicates a statistically significant increase. * indicates a statistically significant decrease. Bars represent mean ± S.D. (n = 5 per group).…”

CS-US experiment. by Elías M. Fernández Santoro (22470299)

“…PF5(US) responds the least to US. (C) Mean instantaneous Hilbert frequency of STOs, smoothed using 51ms 3rd order Savitzky–Golay filter.…”

WTA stimulates in vitro T-cell activation by a MHC-II dependent mechanism. by Christopher Weidenmaier (240364)

“…Shown are means ± SEM. n = 5. C). WTA induced T-cell proliferation only with Raji cells as APCs but not when APCs were from the MHC II negative cell line RJ2.5.5. …”

Functional characterization of differentiated astrocytes. by In Ki Cho (6494564)

“…<p>(A) Representative traces of ionic currents evoked by ramp protocol (left) and voltage-step protocol (right) in cultured WT, HD, and shHD astrocytes. The holding potentials for all the cells were -60mV. …”

Representative immunoblots of GSK3β and Akt expression. by Minxian Dai (127310)

“…PbA-infected mice demonstrated a 32% decrease in phospho-GSK3β (S9) expression compared to controls (n = 8 Con, 7 PbA) and a 23% decrease compared to mice infected with PbN (n = 7 PbA, 6 PbN). …”

Hyper-Hypo study: A Retrospective Observational Study of Neonatal Hypoglycemia Related to Maternal Hypertension by Thiruveni Ramkumar (17075051)

“…However, a sub-group comparison of neonates (with initial blood glucose <2.6 mmol/L) showed methyldopa to be marginally associated with a 2 mmol/L decrease from the mean initial blood glucose, mean 1.6 ± 0.5 mmol/L, and methyldopa (1.4 ± 0.5 mmol/L; p= .045). …”

MSCs on endothelial ECM appeared more spindle-like morphology. by Ming-Kang Lee (4401568)

“…MSC-ECM showed drastic decrease of ratio from p2 to p4 (<i>p</i> < 0.001), leaving no significant difference compared to control. ns: not significant as <i>p</i> > 0.05; *: <i>p</i> < 0.05; **: <i>p</i> < 0.01; ***: <i>p</i> < 0.001.…”

Image3_Impact of the Pilot Volume-Based Drug Purchasing Policy in China: Interrupted Time-Series Analysis with Controls.TIFF by Yilin Chen (678552)

Image1_Impact of the Pilot Volume-Based Drug Purchasing Policy in China: Interrupted Time-Series Analysis with Controls.TIFF by Yilin Chen (678552)

Image_9_Interplay Between Plasma Membrane Lipid Alteration, Oxidative Stress and Calcium-Based Mechanism for Extracellular Vesicle Biogenesis From Erythrocytes During Blood Storage... by Anne-Sophie Cloos (9082913)