Microcystins as new therapeutic agents for OATP1B3 expressing tumors _ Poster at ICNPR2012.pdf by Timo Niedermeyer (98677)

“…In fact, in our initial screening of 20 microcystins, we have found four microcystin structural variants with an IC₅₀ in the low nanomolecular range and with transporter selectivity that favors OATP1B3 over OATP1B1 by a factor of more than ten. …”

Reaching the Unreachable: Providing STI Control Services to Female Sex Workers via Mobile Team Outreach by Pablo E. Campos (302579)

“…<div><p>Background</p><p>As part of a community-randomized trial of a multicomponent intervention to prevent sexually transmitted infections, we created Mobile Teams (MTs) in ten intervention cities across Peru to improve outreach to female sex workers (FSW) for strengthened STI prevention services. …”

Supplementary Material for: Protection on Skin Aging Mediated by Antiapoptosis Effects of the Water Lily (<b><i>Nymphaea Tetragona</i></b> Georgi) via Reactive Oxygen Species Scave... by Park G. (4141492)

“…<b><i>Results:</i></b> We investigated the protective effects of WLRE against UVB-induced mitochondria-mediated apoptosis. …”

Image_1_A Label-Free Quantitative Proteomic Analysis of Mouse Neutrophil Extracellular Trap Formation Induced by Streptococcus suis or Phorbol Myristate Acetate (PMA).PDF by Xiaoping Wang (110673)

“…Of these peptidases, MMP-8 expression was obviously decreased in response to PMA, but it was not significantly changed in response to S. suis. …”

The gut-brain axis underlying hepatic encephalopathy in liver cirrhosis by Xiaolong He (19696763)

“…Up to 50-70% of liver cirrhosis patients develop hepatic encephalopathy (HE), which is closely related to gut microbiota dysbiosis, with unclear mechanism. …”

Table_6_Bt GS57 Interaction With Gut Microbiota Accelerates Spodoptera exigua Mortality.XLS by Yazi Li (4162948)

“…In turn, loss of gut microbiota significantly decreased the B. thuringiensis susceptibility of S. exigua larvae. …”

Table_5_Bt GS57 Interaction With Gut Microbiota Accelerates Spodoptera exigua Mortality.XLS by Yazi Li (4162948)

“…In turn, loss of gut microbiota significantly decreased the B. thuringiensis susceptibility of S. exigua larvae. …”

A Novel Nonsense Mutation in the <em>DMP1</em> Gene Identified by a Genome-Wide Association Study Is Responsible for Inherited Rickets in Corriedale Sheep by Xia Zhao (215170)

“…<div><p>Inherited rickets of Corriedale sheep is characterized by decreased growth rate, thoracic lordosis and angular limb deformities. …”

Image 1_Downregulated PTEN and aberrant JAK–STAT signal pathway in essential thrombocythemia patients.jpeg by Lin Luo (429475)

“…The JAK2 V617F mutation is detected in 50%–60% of patients with ET and can drive ET occurrence through ligand-independent activation of the thrombopoietin (TPO) receptor, resulting in JAK/STAT pathway signaling. …”

Biodiversity of the Deep-Sea Continental Margin Bordering the Gulf of Maine (NW Atlantic): Relationships among Sub-Regions and to Shelf Systems by Noreen E. Kelly (236920)

“…Non-parametric estimators of species richness suggest a minimum of 50% of the deep-sea species inventory remains to be discovered.…”

Table_2_Photosynthetic response of Chlamydomonas reinhardtii and Chlamydomonas sp. 1710 to zinc toxicity.XLSX by Di Zhan (14842687)

“…The results demonstrated that Chlamydomonas sp. 1710 was much more tolerant to Zn than C. reinhardtii, with the half-maximal inhibitory concentration (IC50) values of 225.4 mg/L and 23.4  mg/L, respectively. …”

Influence of COS on the activation of NF-κB in retina and RGC-5 cells. by I-Mo Fang (470460)

“…For quantitative immunohistochemistry for NF-κB p65, we first determined the p65 index, which could be measured and calculated from the following formula: Σ [(p65 staining density-threshold) × area (pixels)] / total cell number. …”

Exercise-linked skeletal irisin ameliorates diabetes-associated osteoporosis by inhibiting the oxidative damage-dependent miR-150-FNDC5/pyroptosis axis by Jyotirmaya Behera (11496551)

“…However, the impact of EX on the progression of bone loss and deterioration of mechanical strength in type 2 diabetic (T2DM) mice remains unexplored. In the present study, we investigated the effect of EX on bone mass and mechanical quality using a diabetic mouse model. …”

Image 1_Temporary trigeminal ganglion stimulation can improve zoster-related trigeminal neuralgia: a retrospective study in a single center.tif by Kan Yue (1378518)

“…Among these patients, five (56%) experienced more than 50% pain relief at discharge. At the six-month follow-up, the mean VAS score decreased from preoperative 6.1 ± 1.5 to 2.5 ± 1.9, demonstrating a statistically significant reduction (t = 4.36, p < 0.05). …”

DataSheet_1_Emodin Inhibits Inflammation, Carcinogenesis, and Cancer Progression in the AOM/DSS Model of Colitis-Associated Intestinal Tumorigenesis.pdf by Yunsha Zhang (9961550)

“…At all three time points, Emodin (50 mg/kg) reduced inflammatory cell (i.e. CD11b⁺ and F4/80⁺) recruitment, cytokine (i.e. …”

Table_2_Characteristics of the Microbial Community in the Production of Chinese Rice-Flavor Baijiu and Comparisons With the Microflora of Other Flavors of Baijiu.XLSX by Yuanliang Hu (517504)

“…The bacterial diversity index first increased and then decreased, while the diversity of fungi showed an increasing trend. …”

Table_2_Characteristic of Perineural Invasion in Hilar Cholangiocarcinoma Based on Whole-Mount Histologic Large Sections of Liver.docx by Si-Yuan Wang (6307619)

“…Extrahepatic and intrahepatic PNI were identified in 20 (100%) patients and 1 (5.0%) patient, respectively. Vessel density decreased in most invaded nerves presented by CD-34, which correlated with 100% of poorly differentiated and 83% of moderately differentiated tumors (P<0.008).…”

Table 1_Downregulated PTEN and aberrant JAK–STAT signal pathway in essential thrombocythemia patients.docx by Lin Luo (429475)

“…The JAK2 V617F mutation is detected in 50%–60% of patients with ET and can drive ET occurrence through ligand-independent activation of the thrombopoietin (TPO) receptor, resulting in JAK/STAT pathway signaling. …”

Video_2_Aging dysregulates neutrophil extracellular trap formation in response to HIV in blood and genital tissues.mp4 by Laura Moreno de Lara (12966254)

“…However, how NET formation is triggered by HIV in different tissues and whether this mechanism is affected by aging remain unknown. We demonstrate that the mechanisms that trigger NET release in response to HIV are different in blood and genital tissues, and that NET release decreases with aging. …”

Data_Sheet_1_Effect of Virtual Reality on Stress Reduction and Change of Physiological Parameters Including Heart Rate Variability in People With High Stress: An Open Randomized Cr... by Hyewon Kim (1788081)

“…VR and biofeedback significantly decreased STAI-X1 and NRS from the stress phase to the relaxation phase, while the difference of effect between VR and biofeedback was not significant. …”