datasheet1_Antihypertensive Effect of a Novel Angiotensin II Receptor Blocker Fluorophenyl Benzimidazole: Contribution of cGMP, Voltage-dependent Calcium Channels, and BKCa Channel... by Hina Iqbal (10496588)

“…<p>Background: The current study presents the novel angiotensin II receptor blocker fluorophenyl benzimidazole (FPD) as an antihypertensive agent in the SHR model of hypertension. We investigated the role of cGMP, voltage-dependent L-type calcium channels, and BK_Ca channels in the vasorelaxant mechanisms of FPD in the rat superior mesenteric artery.…”

datasheet1_Exposure-Response Modeling to Support Dosing Selection for Phase IIb Development of Kukoamine B in Sepsis Patients.docx by Huanhuan Wang (309941)

“…</p><p>Conclusion: We built an exposure-response model characterizing the pharmacological effect of kukoamine B from the standard care therapy in sepsis patients. …”

Table_1_Risk and Prognosis of Secondary Rectal Cancer After Radiation Therapy for Pelvic Cancer.docx by Runkun Yang (6079922)

“…Primary cancers were located in the prostate (50.83%), bladder (24.18%), corpus uterus (16.26%), cervix (5.83%), and ovary (2.91%). …”

Image 5_Global burden of varicella and herpes zoster across 204 countries, 1990–2021: a temporal trend analysis in the era of the COVID-19 pandemic and projections to 2036.tiff by Zilun Wu (18696883)

“…Mortality and DALYs declined significantly, with age-standardized mortality rates (ASMR) and DALYs rates (ASDR) decreasing by 50.0 and 36.3%, respectively. A stark disparity remains, with low-SDI regions accounting for over 67% of deaths and DALYs. …”

Table 1_Global burden of varicella and herpes zoster across 204 countries, 1990–2021: a temporal trend analysis in the era of the COVID-19 pandemic and projections to 2036.xlsx by Zilun Wu (18696883)

“…Mortality and DALYs declined significantly, with age-standardized mortality rates (ASMR) and DALYs rates (ASDR) decreasing by 50.0 and 36.3%, respectively. A stark disparity remains, with low-SDI regions accounting for over 67% of deaths and DALYs. …”

Image_7_Identification and Functional Characterization of Sugarcane Invertase Inhibitor (ShINH1): A Potential Candidate for Reducing Pre- and Post-harvest Loss of Sucrose in Sugarc... by Suresha G. Shivalingamurthy (5169917)

“…INVINH proteins are small (18 kDa) members of the pectin methylesterase inhibitor superfamily and they are moderately conserved across plants. In the present study, we identified two INVINH genes from sugarcane, ShINH1 and ShINH2. …”

Data_Sheet_1_Donor-Related Risk Factors for Graft Decompensation Following Descemet's Stripping Automated Endothelial Keratoplasty.PDF by Sota Nishisako (12044570)

“…This failure was associated with donor pseudophakic lens status (hazard ratio [HR]; 2.67, CI; 1.50–4.76, P = 0.001) and preoperative endothelial folds (HR; 2.82, CI; 1.20–6.62, P = 0.02). …”

DataSheet_1_Intercropping of wheat alleviates the adverse effects of phenolic acids on faba bean.doc by Yiran Zheng (2562298)

“…In the pot experiment, it was found that compared with the control, different concentrations of benzoic acid and cinnamic acid (50, 100, and 200 mg·L⁻¹) significantly increased the content of H₂O₂ and O₂⁻ in faba bean, decreased the activity and gene expression of antioxidant enzymes SOD and CAT, and damaged cell membrane structure. …”

Comparative Proteomic Analysis between the Domesticated Silkworm (<i>Bombyx mori</i>) Reared on Fresh Mulberry Leaves and on Artificial Diet by Zhong-hua Zhou (2370538)

“…To gain an insight into the effects of different diets on growth and development of the domesticated silkworm at protein level, we employed comparative proteomic approach to investigate the proteomic differences of midgut, hemolymph, fat body and posterior silk gland of the silkworms reared on fresh mulberry leaves and on artificial diet. …”

Image_3_Identification and Functional Characterization of Sugarcane Invertase Inhibitor (ShINH1): A Potential Candidate for Reducing Pre- and Post-harvest Loss of Sucrose in Sugarc... by Suresha G. Shivalingamurthy (5169917)

“…INVINH proteins are small (18 kDa) members of the pectin methylesterase inhibitor superfamily and they are moderately conserved across plants. In the present study, we identified two INVINH genes from sugarcane, ShINH1 and ShINH2. …”

Data_Sheet_1_Biocontrol Potential of a Novel Endophytic Bacterium From Mulberry (Morus) Tree.docx by Sen Xie (8349420)

“…An integrative approach combining traditional natural product chemistry, activity bioassays, and high-resolution mass spectrometry confirmed that strain ZJU1 uses a blend of antimicrobials including peptides and volatile organic compounds to oppose Botrytis cinerea, a major phytopathogenic fungus causing mulberry gray mold disease. We showed that the inoculation of endophyte-free plants with ZJU1 significantly decreased both leaf necrosis and mortality under field conditions. …”

Image 2_Global burden of varicella and herpes zoster across 204 countries, 1990–2021: a temporal trend analysis in the era of the COVID-19 pandemic and projections to 2036.tiff by Zilun Wu (18696883)

“…Mortality and DALYs declined significantly, with age-standardized mortality rates (ASMR) and DALYs rates (ASDR) decreasing by 50.0 and 36.3%, respectively. A stark disparity remains, with low-SDI regions accounting for over 67% of deaths and DALYs. …”

Table_1_Short Body Height and Pre-pregnancy Overweight for Increased Risk of Gestational Diabetes Mellitus: A Population-Based Cohort Study.DOC by Jing Li (10611)

“…At 24–28 weeks of gestation, women underwent a 50-g 1-h glucose challenge test (GCT) followed by a 75-g 2-h oral glucose tolerance test (OGTT) if the GCT result was ≥7.8 mmol/L. …”

Inference under various sources of process variability. by Susanne Pinto (13767952)

“…<p>For the different scenario’s we show the precision, recall and the F1-score. …”

Data_Sheet_7_Bacteroides abundance drives birth mode dependent infant gut microbiota developmental trajectories.DOCX by Dollwin Matharu (13914927)

“…However, we did not observe an increase in functional alpha diversity, which was stable and comparable with the mother samples throughout all the sampling points. …”

Supplementary file 1_Effects of the monolaurin based feed additive MGOsyn on methane production, rumen fermentation, and microbial communities using rumen fluid from Hanwoo steers... by Mi Ae Park (18264867)

“…After 24 h of incubation at 39 °C, MGOsyn increased propionate production by 50% in a dose dependent manner, while reducing methane emission by 61%, acetate proportion and the acetate to propionate ratio. …”

datasheet2_Farnesyl Transferase Inhibitor Lonafarnib Enhances α7nAChR Expression Through Inhibiting DNA Methylation of CHRNA7 and Increases α7nAChR Membrane Trafficking.xlsx by Tingting Chen (111216)

“…Herein, we show that lonafarnib dose dependently enhances the amplitude of ACh-evoked inward currents (I_ACh), owning to the increased α7nAChR expression and membrane trafficking. …”

Table1_Kinetics of Heterogeneous Reaction of H2O2 and SO2 on Coal Fly Ash: Temperature Effect and Their Synergistic Effects.DOCX by Li Zhou (54356)

“…As a function of temperature, the initial uptake coefficients of H₂O₂ and SO₂ on coal fly ash were (0.48–1.65) × 10⁻⁴ and (1.50–8.54) × 10⁻⁵, respectively, which decreased with an increase in temperature. …”

MicroRNA-451a, microRNA-34a-5p, and microRNA-221-3p as predictors of response to antidepressant treatment by Wei-Hong Kuang (5255186)

“…Paroxetine was markedly effective in 50 patients who also displayed an increased level of miRNA-451a but reduced levels of miRNA-34a-5p and miRNA-221-3p. …”

Data_Sheet_1_No Impact of Fluconazole to Echinocandins Replacement as First-Line Therapy on the Epidemiology of Yeast Fungemia (Hospital-Driven Active Surveillance, 2004–2017, Pari... by Stéphane Bretagne (43201)

“…The mean mortality rate within 30 days was 38.5% (1,103/2,868) and significantly higher in intensive care units (690/1,358, 50.8%) than outside (413/1,510, 27.4%, p < 0.0001) without significant change over time. …”