Data_Sheet_1_The Selective Antagonism of Adenosine A2B Receptors Reduces the Synaptic Failure and Neuronal Death Induced by Oxygen and Glucose Deprivation in Rat CA1 Hippocampus in... by Irene Fusco (5134250)

“…Seven minutes OGD was applied in the presence of the selective adenosine A_2B receptor antagonists MRS1754 (500 nM) or PSB603 (50 nM), separately administered 15 min before, during and 5 min after OGD. …”

Acute effect of timolol on intracellular global Ca²⁺ changes, and the basal levels of intracellular both free Zn²⁺ and Ca²⁺ in ventricular hypergly... by Erkan Tuncay (438815)

“…(C) To record basal levels of both intracellular free Zn²⁺ and Ca²⁺ in resting cells in parallel, we used a ratiometric Fura-2 (4-µM Fura-2 AM) loaded cells and 50-µM N,N,N′,N′-tetrakis (2-pyridylmethyl) ethylenediamine (TPEN) (for more information about methods, see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0071014#pone.0071014-Tuncay1" target="_blank">[28]</a>). …”

Table_13_Longitudinal Analysis of Antibody Responses to the mRNA BNT162b2 Vaccine in Patients Undergoing Maintenance Hemodialysis: A 6-Month Follow-Up.pdf by André Weigert (7888712)

“…Anti-spike IgG, IgM, and IgA levels decreased at t3, with IgG levels further waning at t4 and resulting in >30% seronegativity. …”

Table_12_Longitudinal Analysis of Antibody Responses to the mRNA BNT162b2 Vaccine in Patients Undergoing Maintenance Hemodialysis: A 6-Month Follow-Up.pdf by André Weigert (7888712)

“…Anti-spike IgG, IgM, and IgA levels decreased at t3, with IgG levels further waning at t4 and resulting in >30% seronegativity. …”

Data_Sheet_1_Outcomes of patients with acute respiratory failure on veno-venous extracorporeal membrane oxygenation requiring additional circulatory support by veno-venoarterial ex... by Rolf Erlebach (12614975)

“…Vasoactive-inotropic score decreased from 53 (12–123) at V-VA ECMO upgrade to 9 (3–37) after 24 h of V-VA ECMO support. …”

Absence of the ER Cation Channel <i>TMEM38B</i>/TRIC-B Disrupts Intracellular Calcium Homeostasis and Dysregulates Collagen Synthesis in Recessive Osteogenesis Imperfecta by Wayne A. Cabral (589450)

“…The molecular mechanisms by which <i>TMEM38B</i> mutations cause OI are unknown. We identified 3 probands with recessive defects in <i>TMEM38B</i>. …”

Table_6_Longitudinal Analysis of Antibody Responses to the mRNA BNT162b2 Vaccine in Patients Undergoing Maintenance Hemodialysis: A 6-Month Follow-Up.pdf by André Weigert (7888712)

“…Anti-spike IgG, IgM, and IgA levels decreased at t3, with IgG levels further waning at t4 and resulting in >30% seronegativity. …”

The ORF7a protein of SARS-CoV-2 initiates autophagy and limits autophagosome-lysosome fusion via degradation of SNAP29 to promote virus replication by Peili Hou (4737219)

“…However, how SARS-CoV-2 mediates the subversion of the macroautophagy/autophagy pathway remains largely unclear. In this study, we demonstrate that overexpression of the SARS-CoV-2 ORF7a protein activates LC3-II and leads to the accumulation of autophagosomes in multiple cell lines, while knockdown of the viral <i>ORF7a</i> gene via shRNAs targeting <i>ORF7a</i> sgRNA during SARS-CoV-2 infection decreased autophagy levels. …”

Table_11_Longitudinal Analysis of Antibody Responses to the mRNA BNT162b2 Vaccine in Patients Undergoing Maintenance Hemodialysis: A 6-Month Follow-Up.pdf by André Weigert (7888712)

“…Anti-spike IgG, IgM, and IgA levels decreased at t3, with IgG levels further waning at t4 and resulting in >30% seronegativity. …”

File S1 - Impaired Functionality of Antiviral T Cells in G-CSF Mobilized Stem Cell Donors: Implications for the Selection of CTL Donor by Carola E. Bunse (492512)

“…As apheresis and graft processing took longer, some samples were analyzed later. Thus, we evaluated the influence of storage time and temperature on the reliability of the results. …”

Muscle fiber hypertrophy in response to 6 weeks of high-volume resistance training in trained young men is largely attributed to sarcoplasmic hypertrophy by Cody T. Haun (4183900)

“…The 15 fCSA hypertrophic responders experienced a +23% increase in mean fCSA from PRE to W6 (p<0.001) and, while muscle glycogen concentrations remained unaltered, citrate synthase activity levels decreased by 24% (p<0.001) suggesting mitochondrial volume decreased. …”

Table_1_Granulocyte Colony-Stimulating Factor Accelerates the Recovery of Hepatitis B Virus-Related Acute-on-Chronic Liver Failure by Promoting M2-Like Transition of Monocytes.docx by Jingjing Tong (2572018)

“…In the G-CSF-treated group, the monocyte counts on days 0 and 7 were independently associated with an evaluated mortality risk in the fully adjusted model (Model 3) [at day 0: hazard ratio (HR) 95% confidence interval (CI): 15.48 (3.60, 66.66), P = 0.0002; at day 7: HR (95% CI): 1.10 (0.50, 2.43), P=0.8080]. Further analysis showed that after treatment with G-CSF in HBV-ACLF patients, the expression of M1-like markers (HLA-DR and CD86) in monocytes decreased (HLA-DR: P = 0.0148; CD86: P = 0.0764). …”

DataSheet1_Mechanism of Tripterygium wilfordii Hook.F.- Trichosanthes kirilowii Maxim decoction in treatment of diabetic kidney disease based on network pharmacology and molecular... by Lingfei Lu (5400374)

“…GO function enrichment analysis included 2,143, 50, and 167 GO terms for biological processes (BPs), cellular composition (CCs), and molecular functions (MFs), respectively. …”

Data_Sheet_1_Food Web Functions and Interactions During Spring and Summer in the Arctic Water Inflow Region: Investigated Through Inverse Modeling.docx by Kalle Olli (288500)

“…<p>We used inverse modeling to reconstruct major planktonic food web carbon flows in the Atlantic Water inflow, east and north of Svalbard during spring (18–25 May) and summer (9–13 August), 2014. …”

Data_Sheet_1_Functional Exhaustion of Type I and II Interferons Production in Severe COVID-19 Patients.docx by Caroline Ruetsch (9691565)

“…In this prospective study we compared the immunological profile of 101 COVID-19 patients with either mild, moderate or severe form of the disease according to the WHO classification, as well as of 50 healthy subjects, in order to identify functional immune factors independently associated with severe forms of COVID-19. …”

Data_Sheet_1_Cost-Utility Analysis of the Integrated Care Models for the Management of Hypertension Patients: A Quasi-Experiment in Southwest Rural China.PDF by Xiatong Ke (11080686)

“…Compared with Option 1, Option 2 yielded an additional 0.477 QALYs, and the cost decreased by $2,237.30, so the ICER was –$4,688.50/QALY, the NMB was $3,000.40, and the NHB was 1.876 QALYs. …”

Impaired TFEB-mediated lysosomal biogenesis promotes the development of pancreatitis in mice and is associated with human pancreatitis by Shaogui Wang (310181)

“…</p> <p><b>Abbreviations:</b> AC: acinar cell; AMY: amylase; ATP6V1A: ATPase, H+ transporting, lysosomal V1 subunit A; ATP6V1B2: ATPase, H+ transporting, lysosomal V1 subunit B2; ATP6V1D: ATPase, H+ transporting, lysosomal V1 subunit D; ATP6V1H: ATPase, H+ transporting, lysosomal V1 subunit H; AV: autophagic vacuole; CDE: choline-deficient, ethionine-supplemented; CLEAR: coordinated lysosomal expression and regulation; CQ: chloroquine; EIF4EBP1: eukaryotic translation initiation factor 4E binding protein 1; EM: electron microscopy; GAPDH: glyceraldehyde-3-phosphate dehydrogenase; GFP: green fluorescent protein; H & E: hematoxylin and eosin; KO: knockout; LAMP1: lysosomal-associated membrane protein 1; MAP1LC3/LC3: microtubule associated protein 1 light chain 3; MAPK1/ERK2: mitogen-activated protein kinase 1; MTORC1: mechanistic target of rapamycin kinase complex 1; ND: normal donor; NEU: neutrophil; PPARGC1A/PGC1α: peroxisome proliferator-activated receptor, gamma, coactivator 1 alpha; RIPA: radio-immunoprecipitation; RPS6: ribosomal protein S6; SQSTM1/p62: sequestosome 1; TFEB: transcription factor EB; TM: tamoxifen; WT: wild-type; ZG: zymogen granule</p>…”

The stereocilia abnormalities of cochlea OHCs in Atoh1-LKB1^-/- mice. by Yuqin Men (783410)

“…*p<0.05; **p<0.01; ***p<0.001 compared with the WT group by Student’s t-test; n = 6 hair cells per genotype.…”

Depletion of Ccr7 activity partially rescues axis formation in <i>ichabod</i> mutants. by Shu-Yu Wu (129447)

“…(G) Ccr7 gain-of-function decreased both levels of endogenous β-catenin and ectopic β-catenin-GFP. …”

Figure 4 from β-Catenin Drives Butyrophilin-like Molecule Loss and γδ T-cell Exclusion in Colon Cancer by Toshiyasu Suzuki (16521576)