Showing 301 - 320 results of 18,664 for search '(( 50 ((ns decrease) OR (we decrease)) ) OR ( 59 ((mean decrease) OR (a decrease)) ))', query time: 0.80s Refine Results
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    Discovery of New Inhibitors of Hepatitis C Virus NS3/4A Protease and Its D168A Mutant by Ittipat Meewan (7455041)

    Published 2019
    “…Several drugs targeting the protease have been developed, but drug-resistant mutant strains emerged. Here, we screened a library and synthesized a novel class of small molecules based on a tryptophan derivative scaffold identified as HCV NS3/4A protease inhibitors that are active against both wild type and mutant form of the protease. …”
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    Directed Evolution of RecA Variants with Enhanced Capacity for Conjugational Recombination by Taejin Kim (472963)

    Published 2015
    “…A <i>recA</i> gene segment encoding a 59 residue segment of the protein (Val79-Ala137), encompassing an extensive subunit-subunit interface region, was subjected to degenerate oligonucleotide-mediated mutagenesis. …”
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