Selective TASK‑1 Inhibitor with a Defined Structure–Activity Relationship Reduces Cancer Cell Proliferation and Viability by Bárbara Arévalo (4053358)

“…Mutation of seven residues to A (I118A, L122A, F125A, Q126A, L232A, I235A, and L239A) markedly decreased the F3-induced inhibition of TASK-1 channels, consistent with the molecular modeling predictions. …”

Selective TASK‑1 Inhibitor with a Defined Structure–Activity Relationship Reduces Cancer Cell Proliferation and Viability by Bárbara Arévalo (4053358)

“…Mutation of seven residues to A (I118A, L122A, F125A, Q126A, L232A, I235A, and L239A) markedly decreased the F3-induced inhibition of TASK-1 channels, consistent with the molecular modeling predictions. …”

TTLL12 knockdown in HEp-2 and DU145 cells decreases cell survival in the presence of nitrotyrosine. by Amit Deshpande (255211)

Expression of non-muscle myosin (NM) IIC in skeletal muscle cells. by Hiroki Hamaguchi (22783780)

Single wavelength dose response kinetics for MS2. 254 = LP 254 nm and 285 = UV LED 285 nm. by Daniel Ma (12698752)

Discovery of IHMT-MST1-58 as a Novel, Potent, and Selective MST1 Inhibitor for the Treatment of Type 1/2 Diabetes by Yun Wu (150224)

Subjects:

Discovery of IHMT-MST1-58 as a Novel, Potent, and Selective MST1 Inhibitor for the Treatment of Type 1/2 Diabetes by Yun Wu (150224)

Subjects:

RhoA gene expression and activity are impacted with increased intracellular 5HT. by Celeste M. Sheftel (9557588)

The S75A mutation of LeishIF4E3 leads to a decrease in granule formation in response to PBS starvation and to a reduced interaction with LeishIF4G-4. by Rohit Shrivastava (6459608)

Definitions of the features selected [50]. by Yu Zhang (12946)

Locomotive activity in the open field test after ICH. by Masatoshi Ohnishi (14587632)

Image1_The serotonin receptor 5-HT2A modulates lifespan and protein feeding in Drosophila melanogaster.pdf by Allyson S. Munneke (14200148)

“…Loss of the 5-HT2A receptor extends lifespan and induces a resistance to changes in dietary protein that are normally detrimental to lifespan. 5-HT2A^−/− null mutant flies also display decreased protein feeding and protein content in the body. …”

Image2_The serotonin receptor 5-HT2A modulates lifespan and protein feeding in Drosophila melanogaster.pdf by Allyson S. Munneke (14200148)

“…Loss of the 5-HT2A receptor extends lifespan and induces a resistance to changes in dietary protein that are normally detrimental to lifespan. 5-HT2A^−/− null mutant flies also display decreased protein feeding and protein content in the body. …”

Image3_The serotonin receptor 5-HT2A modulates lifespan and protein feeding in Drosophila melanogaster.pdf by Allyson S. Munneke (14200148)

“…Loss of the 5-HT2A receptor extends lifespan and induces a resistance to changes in dietary protein that are normally detrimental to lifespan. 5-HT2A^−/− null mutant flies also display decreased protein feeding and protein content in the body. …”

Single and sequential wavelength disinfection kinetics for flow through UV experiments using LP 254 nm and LED 285 nm reactors. by Daniel Ma (12698752)

Video_5_Contribution of 5-HT2 Receptors to the Control of the Spinal Locomotor System in Intact Rats.WMV by Henryk Majczyński (830716)

“…Little is known about the role of 5-HT receptors in the control of voluntary locomotion, so we administered inverse agonists of 5-HT₂ (Cyproheptadine; Cypr), 5-HT_2A neutral antagonist (Volinanserin; Volin), 5-HT_2C neutral antagonist (SB 242084), and 5-HT_2B/2C inverse agonist (SB 206553) receptors intrathecally in intact rats and monitored their effects on unrestrained locomotion. …”

Photooxidation and Cleavage of Ethynylated 9,10-Dimethoxyanthracenes with Acid-Labile Ether Bonds by Manuel M. Pina (20629476)

“…Optical spectroscopy, cyclic voltammetry, and density functional theory calculations reveal that the ethynyl groups decrease the HOMO–LUMO gaps in these acenes. Notably, bis(dimethylanilineethynyl) substituents increase the wavelength of absorbance onset by over 60 nm compared to 9,10-dimethoxyanthracene (DMA). …”

Matrix crosslinking decreases cell migration persistence. by Michael Pamonag (12295175)

Time course of (A) water uptake, (B) leakage of anthocyanins as indexed by the absorbance (520 nm) of the incubation solution; and (C) change in area affected by water soaking. by Grecia Hurtado (10798260)

Recombination of Autodissociated Water Ions in a Nanoscale Pure Water Droplet by Soonho Kwon (1402972)

“…We found that the self-diffusion of water dramatically decreases in droplets with a diameter below 2.2 nm. …”